Published in Nature Medicine, the paper noted that these effects were stronger in people whose biological age (which relates to the health of their cells and tissues) was already older than their chronological age (how many years old they are).
On average, older people who took a multivitamin supplement daily had a biological age four months younger than those who didnβt.
What else did the study find?
The researchers looked at blood samples from just under 1,000 participants of the USβ COSMOS study β a randomised, double-blind trial.
Participants had an average age of 70. Some people took multivitamins, and others didnβt.
Blood samples were taken three times: at the start of the study, and 12 and 24 months after that.
The scientists calculated the biological age of the people in the research by looking for five biological ageing βclocksβ in their blood.
These βclocksβ had to do with the patterns on DNA, changes in which have been linked to a personβs ageing.

After comparing the blood samples, the researchers noted that people who took daily multivitamins showed signs of slower ageing in two of these βclocksβ, which were associated with mortality risk.
Speaking to Nature, study author Howard Sesso said research like this is βnot just identifying how to live longer, but also how to live betterβ.
He noted taking multivitamins βappeared to be on that type of trajectory over two yearsβ.
Does that mean multivitamins will definitely keep me younger?
We donβt know for sure, yet.
The paper said that though βstatistically significant but small effects of daily MVM [multivitamin] supplementation on slowing biological ageing are encouragingβ, additional studies are needed to explore this further.
Still, speaking to Nature, geroscientist Steve Hovarth (who was not involved in the study), said: βThis is a very interesting and rigorous study… The public appetite for knowing whether everyday supplements can genuinely slow ageing is enormous.
βThis study provides some of the most credible evidence we have to date.β
by Amy Glover March 19 2026 HuffPost UK
I hedge my bets and take a multivitamin every few days. Glad to know that folks continue to study this topic!
~ Me too Wille ~