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Household Cleaners May Alter Kids’ Gut Flora And Contribute To Being Overweight, Says Study

Commonly used household disinfectants could increase the risk of young children becoming overweight by altering the makeup of their gut bacteria during the first few months of life, a study suggests.

The study, published Monday in the Canadian Medical Association Journal, analyzed the gut flora of 757 infants at age three to four months and their body mass index, or BMI, at one and three years old, looking at exposure to disinfectants, detergents and eco-friendly products used in the home.

Anita Kozyrskyj, professor of pediatrics at the University of Alberta, is shown in a handout photo. The high use of household disinfectant cleaners is changing the gut flora in babies, leading to them becoming overweight as three-year-olds.

“We found that infants living in households with disinfectants being used at least weekly were twice as likely to have higher levels of the gut microbes Lachnospiraceae at age three to four months,” said principal investigator Anita Kozyrskyj, a professor of pediatrics at the University of Alberta.

Lachnospiraceae is one of many non-pathogenic bacteria that naturally inhabit the human gut.

“When they were three years old, their body mass index was higher than children not exposed to heavy home use of disinfectants as an infant,” she added.

Researchers from across Canada looked at data on microbes in infant fecal matter among children enrolled in the Canadian Healthy Infant Longitudinal Development (CHILD) birth cohort. They used World Health Organization growth charts for BMI scores.

Associations with altered gut flora in babies three to four months old were strongest for frequent use of household disinfectants such as multi-surface cleaners, which showed higher levels of Lachnospiraceae.

Kozyrskyj said researchers also found there was a greater increase in levels of those bacteria in children whose parents reported more frequent cleaning with disinfectants.

“As the microbiome develops over the first year of life, these microbes increase in their abundance. So it was a matter of dose,” she said in an interview, noting that studies of piglets have found similar changes in the animals’ gut microbiome when they were exposed to aerosol disinfectants in their enclosures.

However, the same association was not found with detergents or eco-friendly cleaners, the CHILD study found. Babies living in households that used eco-friendly cleaners had different microbiota and were less likely to be overweight as toddlers.

 

“Those infants growing up in households with heavy use of eco cleaners had much lower levels of the gut microbes Enterobacteriaceae (a family of bacteria that includes E. coli). However, we found no evidence that these gut microbiome changes caused the reduced obesity risk,” Kozyrskyj said.

One reason could be that the use of eco-friendly products may be linked to healthier overall maternal lifestyles and eating habits, contributing in turn to the healthier gut microbiomes and weight of infants.

“Antibacterial cleaning products have the capacity to change the environmental microbiome and alter risk for child overweight,” write the authors. “Our study provides novel information regarding the impact of these products on infant gut microbial composition and outcomes of overweight in the same population.”

There are many findings that point to a possible causative role for disinfectants in altering gut flora and subsequently leading to a higher childhood BMI, said Kozyrskyj, noting that in studies of mice, Lachnospiraceae has been shown to cause insulin resistance and increased fat storage.

“I would be comfortable in saying the high use of disinfectants had a contributory role … My advice would be to not overuse them,” she said.
“Some people might say maybe go for an alternative, go for the eco product instead of the disinfectants as a cleaning agent.”

In a related CMAJ commentary, epidemiologists Dr. Noel Mueller and Moira Differding of the Johns Hopkins Bloomberg School of Public Health write: “There is biologic plausibility to the finding that early-life exposure to disinfectants may increase risk of childhood obesity through the alterations in bacteria within the Lachnospiraceae family.”

They call for further studies “to explore the intriguing possibility that use of household disinfectants might contribute to the complex causes of obesity through microbially mediated mechanisms.”

Kozyrskyj agreed, saying there is a need for further research that classifies cleaning products by their ingredients, with an analysis of their potential individual effects.

Mon., Sept. 17, 2018
 
By SHERYL UBELACKER     The Canadian Press
 
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11 Sneaky Things Other Than Food & Exercise That May Affect Your Weight

And how to make them work in your favor

The great recession

What do economics have to do with health? At most universities they’re not even in the same building! But it turns out that a dip in the economy can lead to a rise in our weight according to a study done by John Hopkins. Researchers found that from 2008 to 2012—the period known as the great recession—weight gain was strongly correlated with the rise in unemployment, increasing the risk of obesity by 21 percent. This makes sense as one of the first things to go when our budgets get tight are luxuries like health food and gym memberships, not to mention the loss of health insurance that often accompanies a job loss. However, it may help to remember that there are many low-cost or free ways to protect your health—and an investment in you is the best one you can make.

How high you are

No we’re not talking about the wave of pot legalization sweeping the country (although that probably would affect your weight too) but rather how high up you live. There’s a reason that Colorado is the both the slimmest and the steepest state in the nation. The altitude at which you live is strongly correlated with your weight, with each gain in altitude corresponding with a drop in weight, according to a study done by the U.S. Air Force. But don’t sell your beach-front property and head for the hills just yet—the effect can be balanced out by other factors known to prevent against obesity where you live, like outdoor greenery, strong social ties, and opportunities to go outside. Case in point: Hawaii is the third thinnest state in America, and it’s the definition of sea level.

 

It’s a generation thing

Ever wondered why your grandma never exercised a day in her life and yet wore a tiny wedding dress that you could never hope to fit into even though you run marathons? Some of it may be due to the difference in generations you were both born into. Bad news for young ‘uns: Millennials, Gen Y, and Gen X all need to eat less and exercise more to stave off obesity than their forefathers did, according to a study from York University. And it’s not just the fact that we have Netflix and take out at our fingertips. Rather, the researchers found that the average metabolism of both men and women has slowed, even after controlling for factors like disease, diet, and fitness. Why? We have no solid answers yet but in the meantime, if you’re under 40 at least you can take comfort that you’re not alone in your struggle.

That cursed smog

The effects of environmental pollutants go far beyond wheezing and sneezing. Rats exposed to highly polluted air were not only much more likely to become obese, according to a study done by Duke University, but also had a greater risk of heart disease, diabetes, and metabolic syndrome. And it’s not just limited to rodents. People who live close to roadways with a high level of air pollution are also more likely to gain weight, says a study from the University of Southern California. Unfortunately air pollution is likely not under your direct control but we can all work together to lobby for and implement clean-air policies where we live, making for both a healthier physical and celestial body.

Your thermostat

Our delightfully warm and cozy homes and offices might be partly responsible for our less-delightful expanding waistlines, say researchers in a study published in the journal Cell. The scientists found that regular exposure to mildly cold weather—as would have been normal in the days before programmable thermostats—helps the human body regulate a healthy weight. The chilly air seems to increase metabolism by making the body work harder to cope with the changing conditions. Some proponents of “cold therapy” take daily ice baths or “shiver walks” but you don’t have to be that extreme to see results, say the researchers. Just lowering your thermostat by a few degrees or turning the shower briefly to cold can help.
scale

How many antibiotics you’ve taken

Antibiotics are one of the biggest miracles of modern medicine, no doubt about it. But those infection-fighting drugs may have unintended consequences. The more antibiotics a person takes during their lifetime, particularly during early childhood, the greater their risk of becoming obese, according to an NYU study. Researchers speculate that it has to do with killing healthy gut bacteria, decimating your microbiome along with the bad bugs, as good bacteria has been shown to help prevent weight gain. But if you were the kid with chronic ear infections, don’t fret, you can rebuild your good gut bacteria by taking a probiotic and eating plenty of fermented foods such as yogurt, kefir, sauerkraut, and kimchi.

Fido and Fifi

Owning a pet, particularly a dog, slashes the human companion’s risk of obesity, says the American Heart Association. Why? Dogs need to be walked daily and are often quite persistent, encouraging their owners to walk as well. But it’s not just the extra exercise, especially since 40 percent of dog owners confess to not walking their dog on a regular basis. The researchers add that petting an animal greatly reduces stress and depression, two other known risk factors for weight gain. So if you do have a dog, make sure to walk them daily, and in the meantime soak up all the snuggles, wet kisses, and purrs you can.

The number on your paycheck

Income is one of the biggest factors correlated with obesity, with poor Americans being three times more likely to be obese than richer ones, according to a study published in Nutrition Reviews. Low-income people are less likely to have access to supermarkets with fresh foods (often living in “food deserts”), less likely to have health insurance, and less likely to live in neighborhoods where exercise outdoors is encouraged or even safe. Fortunately this is one area we can all help improve by working to better conditions in our own neighborhoods or helping out others nearby.

Pesticides

Pesticides may help us grow stronger and more plentiful crops but many of the chemicals used in popular formulations are known “endocrine disruptors”: They interfere with your body’s metabolic systems. Pesticides hijack our metabolism by mimicking, blocking, or otherwise interfering with the body’s natural hormones, according to a report issued by The Endocrine Society. Regular exposure to pesticides through food was correlated with an increase risk of both obesity and diabetes. Buying all organic may be one solution but for many people that doesn’t fit in the budget. If money’s tight you can also decrease your pesticide load by avoiding, or only buying organic of, the “dirty dozen“, the most contaminated produce. Or you can always try growing some of your own fruits and vegetables. (Bonus: Gardening is great exercise!)

How many trees you can count from your window

Close proximity to parks, trails, and other types of green spaces is linked with lower body weight, according to research done by the American Diabetes Association. Being able to see, and more importantly walk to, greenery encouraged people to exercise more and made it feel, well, less like exercise. Parks make physical exertion feel like fun but even if you’re not using them to exercise, simply being in the presence of nature has been shown to reduce stress, lower weight and improve your health overall. The vast majority of Americans already live within walking distance of some type of park so get out there and explore your neighborhood.

All that stuff on the food label you don’t recognize

You already know that processed foods do no favors for your waistline but it turns out it’s not just the empty calories and trans fats doing the damage. Some of the most popular food additives are linked with weight gain and obesity, according to a study done by Georgia State University. Emulsifiers, which are added to most processed foods for texture and to extend shelf life, are one of the worst offenders as they interfere with good gut bacteria. But some artificial flavorings, artificial sweeteners, preservatives, and even the food packaging have also been linked in research to obesity.

Charlotte Hilton Andersen  
source: www.rd.com


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Fun Fact Friday

  • Eat slowly. Your body takes 20 minutes to recognize it’s full.

  • Humans cannot walk in a straight line without a visual point – When blindfolded, we will gradually walk in a circle.

 

  • People who regularly eat dinner or breakfast in restaurants double their risk of becoming obese.

  • Oddly enough, people on the Internet are more real than people in real life. The ability to act anonymously makes us much more genuine.

Happy Friday!
source: @Fact


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Child And Teen Obesity Soars Tenfold Worldwide In 40 Years: WHO Report

GENEVA (Reuters) – The number of obese children and adolescents worldwide has jumped tenfold in the past 40 years and the rise is accelerating in low- and middle-income countries, especially in Asia, a major study said on Wednesday.

Childhood and teen obesity rates have leveled off in the United States, north-western Europe and other rich countries, but remain “unacceptably high” there, researchers at Imperial College London and the World Health Organization (WHO) said.

“Over 40 years we have gone from about 11 million to a more than tenfold increase to over 120 million obese children and adolescents throughout the world,” lead author Majid Ezzati of Imperial’s School of Public Health, told a news conference.

This means that nearly 8 percent of boys and nearly 6 percent of girls worldwide were obese in 2016, against less than one percent for both sexes in 1975.

An additional 213 million children aged 5-19 were overweight last year, but fell below the threshold for obesity, according to the largest ever study, based on height and weight measurements of 129 million people.

The researchers called for better nutrition at home and at school, and more physical exercise to prevent a generation from becoming adults at greater risk of diabetes, heart disease and cancers due to excessive weight.

Clear food labels on salt, sugar and fat content are needed to help consumers make “healthy choices”, the study said.

Taxation and tough restrictions on marketing of junk food should be considered, it said. WHO has already recommended a 20 percent tax on sugary drinks to reduce consumption.

RAPID TRANSITION

South Africa, Egypt and Mexico which had “very low levels of obesity four decades ago” now have among the high rates of obesity in girls, between 20-25 percent, Ezzati said.

“The experience of east Asia and Latin America and the Caribbean show that the transition from underweight to overweight and obesity can be rapid,” the study said.

If current trends continue, in 2022 there will be more obese children and teenagers worldwide than underweight ones, who now number 192 million, half of them in India, the study said.

Polynesia and Micronesia had the highest rates of child obesity last year, 25.4 percent in girls and 22.4 percent in boys, followed by “the high-income English-speaking region” that includes the United States, Canada, Australia, New Zealand, Ireland and Britain.

Among high-income countries, the United States had “the highest obesity rates for girls and boys”, 19.5 percent and 23.3 percent, respectively.

“Children are not getting physical activity in the school days, there is poor food opportunities in many schools, walking and cycling to school is going down in many countries, unsafe in many other countries, and parents are not being given the right, sufficient advice on nutrition,” said Fiona Bull of WHO’s department of non-communicable diseases.
“It’s the changing environments, food, behaviors, portions, consumption patterns have completely changed over the last 40 years. Highly processed food is more available, more marketed and it’s cheaper,” she said.

 

Reporting by Stephanie Nebehay Editing by Jeremy Gaunt     OCTOBER 10, 2017 
source: reuters.com


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40% Of Cancers Diagnosed In U.S. Related To Obesity, CDC Says

Add cancer to the many good reasons to strive for a healthy weight

The rates of 12 obesity-related  cancers rose by 7 per cent from 2005 to 2014, an increase that is threatening to reverse progress in reducing the rate of cancer in the United States, U.S. health officials say.

According to the U.S. Centers for Disease Control and Prevention, more than 630,000 people in the United States were diagnosed with a cancer linked with being overweight or obese in 2014.

Obesity-related cancers accounted for about 40 per cent of all cancers diagnosed in the United States in 2014. Although the overall rate of new cancer diagnoses has fallen since the 1990s,  rates of obesity-related cancers have been rising.

“Today’s report shows in some cancers we’re going in the wrong direction,” Dr. Anne Schuchat of the CDC said on a conference call with reporters.

According to the International Agency for Research on Cancer, 13 cancers are associated with overweight and obesity.
They include:

  • Meningioma.
  • Multiple myeloma.
  • Adenocarcinoma of the esophagus.
  • Cancers of the thyroid, postmenopausal breast, gallbladder, stomach, liver, pancreas, kidney, ovaries, uterus and colon and rectum (colorectal).

In 2013-2014, about two out of three U.S. adults were considered overweight or obese. CDC researchers used the U.S. cancer statistics database to see how obesity was affecting cancer rates. Although cancer rates rose in 12 of these cancers from 2005 to 2012, colorectal cancer rates fell by 23 per cent, helped by increases in screening, which prevents new cases by finding growths before they turn into cancer.

Cancers not associated with overweight and obesity fell by 13 per cent.

About half of Americans are not aware of this link, according to Schuchat. The findings suggest that U.S. healthcare providers need to make clear to patients the link between obesity and cancer, and encourage patients to achieve a healthy weight.

“The trends we are reporting today are concerning,” Schuchat said. “There are many good reasons to strive for a healthy weight. Now you can add cancer to the list.”

She said the science linking cancer to obesity is still evolving, and it is not yet clear whether losing weight will help individuals once cancer has taken root.

What is clear is that obesity can raise an individual’s risk of cancer, and that risk may be reduced by maintaining a healthy weight, Schuchat said Tuesday.

Oct 04, 2017
source: www.cbc.ca   Reuters


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Energy Dense Foods May Increase Cancer Risk Regardless Of Obesity Status

Link between high dietary energy density in food and obesity-related cancer in normal weight individuals

Diet is believed to play a role in cancer risk. Current research shows that an estimated 30% of cancers could be prevented through nutritional modifications. While there is a proven link between obesity and certain types of cancer, less is known about how the ratio of energy to food weight, otherwise known as dietary energy density (DED), contributes to cancer risk. To find out, researchers looked at DED in the diets of post-menopausal women and discovered that consuming high DED foods was tied to a 10% increase in obesity-related cancer among normal weight women. Their findings are published in the Journal of the Academy of Nutrition and Dietetics.

DED is a measure of food quality and the relationship of calories to nutrients. The more calories per gram of weight a food has, the higher its DED. Whole foods, including vegetables, fruits, lean protein, and beans are considered low-DED foods because they provide a lot of nutrients using very few calories. Processed foods, like hamburgers and pizza, are considered high-DED foods because you need a larger amount to get necessary nutrients. Previous studies have shown that regular consumption of foods high in DED contributes to weight gain in adults.

In order to gain a better understanding of how DED alone relates to cancer risk, researchers used data on 90,000 postmenopausal women from the Women’s Health Initiative including their diet and any diagnosis of cancer. The team found that women who consumed a diet higher in DED were 10% more likely to develop an obesity-related cancer, independent of body mass index. In fact, the study revealed that the increased risk appeared limited to women who were of a normal weight at enrollment in the program.

 

“The demonstrated effect in normal-weight women in relation to risk for obesity-related cancers is novel and contrary to our hypothesis,” explained lead investigator Cynthia A. Thomson, PhD, RD, Professor of Health Promotion Sciences at the University of Arizona Mel and Enid Zuckerman College of Public Health in Tucson, AZ. “This finding suggests that weight management alone may not protect against obesity-related cancers should women favor a diet pattern indicative of high energy density.”

Although restricting energy dense foods may play a role in weight management, investigators found that weight gain was not solely responsible for the rise in cancer risk among normal weight women in the study. They hypothesize that the higher DED in normal-weight women may cause metabolic dysregulation that is independent of body weight, which is a variable known to increase cancer risk.

While further study is needed to understand how DED may play a role in cancer risk for other populations such as young people and men, this information may help persuade postmenopausal women to choose low DED foods, even if they are already at a healthy body mass index.

“Among normal-weight women, higher DED may be a contributing factor for obesity-related cancers,” concluded Dr. Thomson. “Importantly, DED is a modifiable risk factor. Nutrition interventions targeting energy density as well as other diet-related cancer preventive approaches are warranted to reduce cancer burden among postmenopausal women.”

Story Source:
Materials provided by Elsevier. Note: Content may be edited for style and length.


Journal Reference:

Cynthia A. Thomson, Tracy E. Crane, David O. Garcia, Betsy C. Wertheim, Melanie Hingle, Linda Snetselaar, Mridul Datta, Thomas Rohan, Erin LeBlanc, Rowan T. Chlebowski, Lihong Qi. Association between Dietary Energy Density and Obesity-Associated Cancer: Results from the Women’s Health Initiative. Journal of the Academy of Nutrition and Dietetics, 2017; DOI: 10.1016/j.jand.2017.06.010

source: www.sciencedaily.com    August 17, 2017


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These 5 Preventable Conditions Shorten Lives

More bad news for plus-sized Americans: Obesity is the leading cause of preventable life-years lost in the nation, a new study finds.

Obesity steals more years than diabetes, tobacco, high blood pressure and high cholesterol – the other top preventable health problems that cut Americans’ lives short, according to researchers who analyzed 2014 data.

“Modifiable behavioral risk factors pose a substantial mortality burden in the U.S.,” said study lead author Glen Taksler, an internal medicine researcher at the Cleveland Clinic.

“These preliminary results continue to highlight the importance of weight loss, diabetes management and healthy eating in the U.S. population,” Taksler said in a clinic news release.

Obesity was linked with as much as 47 percent more life-years lost than tobacco, his team said.

Tobacco, meanwhile, had the same effect on life span as high blood pressure, the researchers found.

The researchers noted that three of the top five causes of life-years lost – diabetes, high blood pressure and high cholesterol – can be treated. And helping patients understand treatment methods, options and approaches can have a significant effect, the study authors said.

The findings also emphasize the importance of preventive care, and why it should be a priority for physicians, Taksler’s team said.

However, the researchers acknowledged that some people’s situations may be different than those of the general population. For example, for someone with obesity and alcoholism, drinking may be a more important risk factor than obesity, even though obesity is more significant in the general population.

“The reality is, while we may know the proximate cause of a patient’s death – for example, breast cancer or heart attack – we don’t always know the contributing factor(s), such as tobacco use, obesity, alcohol and family history,” Taksler said. “For each major cause of death, we identified a root cause to understand whether there was a way a person could have lived longer.”

The findings were scheduled for presentation Saturday at the annual meeting of the Society of General Internal Medicine, in Washington, D.C. Research presented at meetings should be considered preliminary until published in a peer-reviewed medical journal.

Obesity steals the most years of all, researchers say

By Robert Preidt     HealthDay Reporter     MONDAY, April 24, 2017
Sources: Cleveland Clinic, news release, April 22, 2017     WebMD News from HealthDay