August 7, 2021
by misterpete4u 3 Comments

3 Mental Problems Linked To Vitamin B12 Deficiency

The deficiency is easy to rectify with diet or supplementation.

Mental confusion can be a sign of vitamin B12 deficiency, research suggests.

People with a B12 deficiency can have problems with their memory and concentration.

Depression symptoms like low mood and low energy are also linked to the deficiency.

Low levels of vitamin B12 can even contribute to brain shrinkage, other studies have suggested.

Around one-in-eight people over 50 are low in vitamin B12 levels, recent research finds.

The rates of deficiency are even higher in those who are older.

Fortunately, these deficiencies are easy to rectify with diet or supplementation.

Good dietary sources of vitamin B12 include fish, poultry, eggs and low-fat milk.

Fortified breakfast cereals also contain vitamin B12.

People who may have difficulty getting enough vitamin B12 include vegetarians, older people and those with some digestive disorders, such as Crohn’s disease.

One study has found that high doses of B vitamins can help reduce the symptoms of schizophrenia.

Schizophrenia is one of the most serious types of mental illness.

It can cause delusions, hallucinations, confused thinking and dramatic changes in behaviour.

The study reviewed 18 different clinical trials, including 832 patients.

It found that high doses of B vitamins helped reduce the symptoms of schizophrenia.

The vitamins were particularly effective if used early on in treatment.

Dr Joseph Firth, the study’s lead author, said:

“Looking at all of the data from clinical trials of vitamin and mineral supplements for schizophrenia to date, we can see that B vitamins effectively improve outcomes for some patients.

This could be an important advance, given that new treatments for this condition are so desperately needed.”

Professor Jerome Sarris, study co-author, said:

“This builds on existing evidence of other food-derived supplements, such as certain amino-acids, been beneficial for people with schizophrenia.”

About the author

Psychologist, Jeremy Dean, PhD is the founder and author of PsyBlog. He holds a doctorate in psychology from University College London and two other advanced degrees in psychology.

He has been writing about scientific research on PsyBlog since 2004.

The study was published in the journal Psychological Medicine (Firth et al., 2017).

August 6, 2021 source: PsyBlog

Vitamin D Reduces the Need for Opioids in Palliative Cancer

Patients with vitamin D deficiency who received vitamin D supplements had a reduced need for pain relief and lower levels of fatigue in palliative cancer treatment, a randomized and placebo-controlled study by researchers at Karolinska Institutet shows. The study is published in the scientific journal Cancers.

Among patients with cancer in the palliative phase, vitamin D deficiency is common. Previous studies have shown that low levels of vitamin D in the blood may be associated with pain, sensitivity to infection, fatigue, depression, and lower self-rated quality of life.

A previous smaller study, which was not randomized or placebo-controlled, suggested that vitamin D supplementation could reduce opioid doses, reduce antibiotic use, and improve the quality of life in patients with advanced cancer.

244 cancer patients with palliative cancer, enrolled in ASIH, (advanced medical home care), took part in the current study in Stockholm during the years 2017-2020.

All study participants had a vitamin D deficiency at the start of the study. They received either 12 weeks of treatment with vitamin D at a relatively high dose (4000 IE/day) or a placebo.

The researchers then measured the change in opioid doses (as a measurement of pain) at 0, 4, 8, and 12 weeks after the start of the study.

“The results showed that vitamin D treatment was well tolerated and that the vitamin D-treated patients had a significantly slower increase in opioid doses than the placebo group during the study period. In addition, they experienced less cancer-related fatigue compared to the placebo group,” says Linda Björkhem-Bergman, senior physician at Stockholms Sjukhem and associate professor at the Department of Neurobiology, Healthcare Sciences, and Society, Karolinska Institutet.

On the other hand, there was no difference between the groups in terms of self-rated quality of life or antibiotic use.

“The effects were quite small, but statistically significant and may have clinical significance for patients with vitamin D deficiency who have cancer in the palliative phase. This is the first time it has been shown that vitamin D treatment for palliative cancer patients can have an effect on both opioid-sensitive pain and fatigue,” says first author of the study Maria Helde Frankling, senior physician at ASIH and postdoc at the Department of Neurobiology, Healthcare Science and Society, Karolinska Institutet.

The study is one of the largest drug studies conducted within ASIH in Sweden. One weakness of the study is the large drop-out rate. Only 150 out of 244 patients were able to complete the 12-week study because many patients died of their cancer during the study.

The study was funded by Region Stockholm (ALF), the Swedish Cancer Society, Stockholms Sjukhems Foundation and was carried out with the support of ASIH Stockholm Södra and ASIH Stockholm Norr.

Story Source:
Materials provided by Karolinska Institutet. Note: Content may be edited for style and length.

Journal Reference:
Maria Helde Frankling, Caritha Klasson, Carina Sandberg, Marie Nordström, Anna Warnqvist, Jenny Bergqvist, Peter Bergman, Linda Björkhem-Bergman. ‘Palliative-D’—Vitamin D Supplementation to Palliative Cancer Patients: A Double Blind, Randomized Placebo-Controlled Multicenter Trial. Cancers, 2021; 13 (15): 3707 DOI: 10.3390/cancers13153707

source: ScienceDaily August 5, 2021

April 3, 2021
by misterpete4u 1 Comment

Feeding the Brain

Our body’s control centre needs a healthy diet

“You can’t wink your eye without nutrients being involved, never mind think, remember, learn, or sleep.” So says brain expert Aileen Burford-Mason, author of The Healthy Brain: Optimize Brain Power at Any Age. Find out more about how to feed your body’s command and control centre.

When people embark on the path to healthy eating, they’re often motivated by a desire to lose weight or to help fend off disease. It’s less common for people to embrace a wholesome diet to boost the well-being of their brain.

This is something that puzzles Toronto-based biochemist, immunologist, and cell biologist Aileen Burford-Mason. An expert in orthomolecular nutrition, she says the brain requires proper nutrition to function optimally. In fact, as the most metabolically active organ of the body, the brain uses nutrients at 10 times the rate of any other tissue or organ in the body.

Our body’s command and control centre

“Over the years, it has really astonished me how many times people have said, ‘Why would the brain need food?’” Burford-Mason says. “You can’t wink your eye without nutrients being involved, never mind think, remember, learn, or sleep. There are nutrients involved in every single function of the body. The purpose to eating is to get all the essential nutrients into us, without which we can’t function.

“Because it has such high needs for nutrition, the brain may be the first to warble when we’re short,” she adds. “It may be the first place to tell us, with anxiety, depression, not being able to sleep. There’s so much evidence now that nutrition is at the root of developing dementia. It’s a huge concern.”

Burford-Mason first became interested in the body’s nutrient needs while studying biochemistry at University College in her native Dublin, Ireland. She went on to complete a PhD in immunology in England. Having emigrated to Canada in 1988, she was formerly an assistant professor in the pathology department at the University of Toronto’s faculty of medicine and director of a cancer research laboratory at Toronto General Hospital. The orthomolecular nutrition consultant is now also the author of The Healthy Brain: Optimize Brain Power at Any Age (Patrick Crean Editions, 2017).

With her book, Burford-Mason wanted to distill complex, scientific information into practical steps people can take to improve the state of their grey matter. Also known as biochemical or functional nutrition, orthomolecular nutrition (which takes its name from the Greek word ortho, meaning correct) uses diet, vitamins, minerals, and other supplements to support the body’s health and healing mechanisms.

What is commonly overlooked by doctors and the public alike, she says, is that, for optimal physiological functioning, the body needs all the nutrients all the time; these compounds all interact with and affect each other.

For instance, it’s well established that people living in Canada are likely to be deficient in vitamin D. However, for the sunshine vitamin to be metabolized, the body needs magnesium.

A well-oiled machine

“It’s like the interactivity of all the components of your car,” Burford-Mason says. “It doesn’t matter whether there’s no gas in the tank or no spark plugs or a wheel is missing; with any of those, you’re going nowhere.

“Even if it’s something small, like a wheel nut missing, eventually something will go wrong; the same thing applies to nutrition. All of the nutrients are needed all the time, and the absence of one, no matter how obscure you might think it is, can compromise the way the others work.

“People have talked about exercise and brain games for brain health; all of this is important, but you can’t keep tweaking spark plugs and making sure there’s air in the tires if you’re forgetting the gas,” she says. “Nutrition has been overlooked.”

Food for thought

Broadly speaking, the best thing people can do to enhance brain health via nutrition is to load up on vegetables, legumes (beans and lentils), and fruit. These foods are abundant in vitamins, minerals, fibre, and phytochemicals, which are plant-based chemicals that help reduce the risk of infections and many conditions, including cancer and heart disease. “Phytochemicals can build up in the brain and protect it from damage,” she says.

You can’t have too many vegetables, legumes, and fruit, though Burford-Mason encourages variety and cautions that people who are diabetic or trying to lose weight will want to limit their intake of fruit and starchy vegetables.

Avoid sugar. “If there is one thing that is damaging to the brain and should be left out of a diet, that is sugar,” she says. “Sugar is the new smoking. We have absolutely everything to be gained from cutting back on sugar or cutting it out. The sugar we get should come from vegetables and fruit.”

Rules for brain-healthy eating

Choose unprocessed foods.
Eat nutrient-dense foods such as eggs, fruits, vegetables, nuts, and seeds.
Lighten the glycemic load. Limit yourself to one serving of starchy food per day, such as bread, potatoes, rice, and pasta.
Eat good fats, such as avocado, seafood, nuts (especially walnuts and almonds), and olive and coconut oils.
Have protein at each meal. Sources include chicken, turkey, tuna, shrimp, cottage cheese, Greek yogurt, eggs, lentils, and tofu.

Tips for picking a multivitamin

If you take nothing else on a daily basis, a multivitamin should be your first choice. “They’re the core of the nutrient regimen, because it’s a little bit of everything,” says Aileen Burford-Mason. “You’re plugging gaps. They’re a jumping-off point, not a total solution.”

Choose a type tailored to your gender and age group.
Look for the widest spectrum of trace minerals; molybdenum is a good indicator of completeness.
Select a multi with at least 25 mg of most of the B vitamins and 400 mcg of folic acid. An imbalance of these two (too much folic acid, not enough Bs) has been linked with memory problems in the elderly.
You may need to supplement magnesium and vitamin C, as their levels will likely be low in a multi.

Must-have supplements

vitamins C, D, E, and K
omega-3 fats (fish oil)
magnesium
vitamin B12

The brain’s need for B vitamins likely exceeds the recommended daily intakes, especially if you exercise vigorously or work your brain hard. Although multis contain ample folic acid, it’s rare to find one that has sufficient B12. Low levels of B12 are linked to age-related cognitive decline, and prolonged B12 deficiency has similar symptoms as vascular dementia.

Additional supplements to consider

L-tyrosine, for stress, anxiety, and memory improvement (recommended for adults only)
L-theanine, for stress, anxiety, “busy brain syndrome,” insomnia, and attention deficit hyperactivity disorder (ADHD)
melatonin, for insomnia

WRITTEN BY Gail Johnson @YVRFitFoodie

Gail Johnson is an award-winning digital, print, and broadcast journalist based in Vancouver.

www.alive.com

March 21, 2020
by misterpete4u 9 Comments

How to Stay Calm and Healthy During a Pandemic

The coronavirus pandemic is understandably causing panic in many people. Yet, fear doesn’t help anything. So how can you remain calm—and healthy—and help others in the process? How can you be a positive emotional contagion that helps not only yourself but others feel better about the global situation?

Buying six months’ worth of toilet paper, paper towels, cleaning goods, and food won’t help. Really.

Yes, it might give you a little peace of mind. I know my full pantry, refrigerator, and freezer (and large package of TP) do, indeed, provide me with a sense of security during this pandemic.

But purchasing more than what you need for a week or two, stockpiling as if the world were ending…that isn’t helpful. First, it leaves others without supplies—ones they might actually need. (Some people are out of toilet paper and just want a few rolls!) Second, the buying frenzy only adds to the emotional upheaval, panic, and overwhelm you and others feel.

So, let’s talk about what will help you stay calm and healthy during a pandemic.

Act Wisely
In North America as in most parts of the world, we are focused on taking precautions and acting wisely. We are practicing social distancing by staying home more, not gathering in large groups, and washing our hands and using hand sanitizer…a lot.

We are also doing other things. My acupuncturist closed his clinic to do a deep clean. My husband is being interviewed virtually for a gig (rather than in person). Companies have asked employees to work from home. My 96-year-old mom’s new doctor told her not to come to the office for a routine visit.

The key is to avoid potential exposure—from you or someone else, like eating out, attending large events, spending time in crowded places, or flying. Yet, you also want to live your life to the fullest extent possible.

How can you live fully while stuck at home? It’s not as hard as it seems.

Stay focused on your priorities and take action in ways that are appropriate and safe. For example, you can hunker down and write your book, shoot and share videos to promote a product, conduct virtual meetings, build the website you never have time to create, declutter, and exercise from the comfort of your home.

Or be a positive force for good. A friend of mine said she had started calling those people she knows who live alone. A neighbor of mine that goes into town daily offered to shop for those in our community who can’t or don’t want to leave their homes.

4 Ways to Stay Calm During a Pandemic

See yourself as a leader and role model. Your job is to be calm and centered amidst the chaos. That means you have to quell your own fear and panic.

Here are four ways to remain calm:

1. Limit your intake of news. I’m not saying you shouldn’t remain informed. Of course, you want to do so! But don’t watch the news incessantly.

I remember after 9/11, I watched identical CNN broadcasts for hours waiting for a new report. I have found myself doing the same in the last few days…watching or listening to the news to hear updated news about the pandemic.

Constant consumption of news just feeds your panic and fear. Watch the news only once or twice per day. In this way, you remain informed without allowing yourself to obsess all day long. I, too, have begun to limit how much I watch the news or consume information about the coronavirus via social media or the Internet.

2. Stay busy. If you have nothing to do, you will find your mind trained on fearful thoughts. Or you will seek out other panicky people on social media or television.

Focus on your agenda. What did you want to get done today? What projects could use your attention? Take action on these things so your mind and body remain busy…and calm.

Plus, being productive will make you feel better in general.

3. Increase your mental, emotional and physical self-care routines. These will provide you with a more peaceful countenance no matter what is going on around you.

Now is the time to increase or start a meditation practice. Try meditating twice daily.

Make sure you exercise daily. Exercise makes you happier and reduces stress. Plus, it helps you remain healthy. Try a quick walk outside to boost your mood.

Train your brain on the positive. What might you gain by staying home for a few weeks? How might you make being housebound a pleasant experience? What might be the outcome of a self-quarantine—for yourself and others?

4. Have faith. It’s been said that faith is more important than fear, and in the case of a pandemic, that’s true.

We know that “this, too, will pass.” So focus on a positive future, one where no one gets the coronavirus, travel bans are lifted, large gatherings are safe, and you no longer need to stay at home.

7 Ways to Take Care of Yourself During a Pandemic

Now is a great time to take a serious look at your health routines. Are you taking good care of yourself? Not only do you want to increase your level of emotional and mental health by staying calm, but you also want to improve your physical health.

To help you boost your immune system and ward off illness, here are seven common-sense things you can start doing today.

1. Wash Your Hands (and More)
You’ve heard this ad nauseam and seen all the cartoons as well, but it’s sound advice. Wash your hands for more extended periods and more often—especially after touching surfaces, shaking hands, handling any items made of plastic, glass, or cardboard. Wash your hands also after opening mail, receiving packages, or putting away groceries.

Along with hand washing comes the following advice: avoid touching your mouth, nose, and eyes (especially if you haven’t washed your hands first).

If you feel unwell or have a compromised immune system, consider wearing a mask, too.

2. Use Hand Sanitizer and Sanitizing Wipes
I know these can be difficult to find right now, but if you have some, use them to clean surfaces and to cleanse your hands after touching anything. Don’t forget to wipe off the plastic or cardboard boxes of food you purchase at stores or any packages your receive via mail delivery services—or wash your hands afterward.

The Internet has a host of articles on making your own hand sanitizer and wipes. So, if you can’t purchase any, make your own.

3. Sleep Enough
If you are working from home or quarantined for any reason—sick or not, sleep needs to become your priority. Actually, even if you are still working, sleep should be non-negotiable.

To boost your immune system, sleep eight hours per night…or more. Sleep helps fight off infectious diseases. In fact, there are studies that show that sleeping less than seven hours increases your chances of getting sick considerably. This is not the time to be sleeping only five or six hours per night!

4. Eat a Healthy Diet
Help your body fight off illness and stay strong by eating healthy foods rather than sweets and junk. You’d be amazed at how much difference a nutrient-rich diet makes on your immune system.

And cook healthy meals at home for the time being. Stop frequenting restaurants, salad bars, and fast-food places. Even take-out or delivery could introduce a source of infection.

5. Boost Your Immune System
If you don’t already take multi-vitamins, start doing so. I could go into a long discussion of what supplements to take, but I’m not an expert or doctor. Find a herbalist or nutritional counselor who can help you determine what supplements are best for you.

There are also a host of herbs that boost your immune system. Of course, check with your doctor before adding anything new to your diet.

Some people will claim that supplements and herbs are effective only because of their placebo effect. It doesn’t matter why they work; all that matters is that they help you stay healthy.

6. Lower Your Stress Level
The immune system reacts badly to stress. Fear and anxiety put your body into the flight-or-fight mode, which is driven by your sympathetic nervous system. This response is your body’s reaction to danger and helps you survive stressful and life-threatening situations.

According to the Cleveland Clinic, “During the fight or flight response, your body is trying to prioritize, so anything it doesn’t need for immediate survival is placed on the back burner. This means that digestion, reproductive and growth hormone production, and tissue repair are all temporarily halted. Instead, your body is using all its energy on the most crucial priorities and functions.”

The article goes on to explain, “Living in a prolonged state of high alert and stress can be detrimental to your physical and mental health.” Indeed, chronic stress is known to suppress immune function and increase susceptibility to disease.

So…again…stay calm! Meditate. Pray. Exercise. Watch funny movies. Go for a walk in the woods or on the beach. Take a nap. Read a book.

Don’t watch the news or engage in conversations about the pandemic that raises your level of stress.

7. Focus on the Positive
Drop the end-of-the-world mindset. Be a positive emotional contagion. Guide conversations toward something other than the pandemic. Be happy and upbeat and help others stop feeding the negative emotional cycle.

And think positive thoughts. Feel grateful for whatever you can—the rain, the sun, your elderly parents’ safety, the paycheck you just received, the spring flowers in bloom, the call from your friend or child, the extra time to read a book, or the new opportunities coming your way.

While you are at it, stop complaining about things that are out of your control, like empty shelves at the supermarket, the kids being home from school, not being able to attend a concert or the theater, or anything else. Complaining doesn’t help you or anyone else.

You will find it easier to stay positive and grateful if you remain present. Stop focusing on the past or the future. Stay in this moment.

This, Too, Shall Pass
Finally, remember, this pandemic will pass. It may take a little while, but the coronavirus will peter out. When it does, you and I—and the entire world—will be more prepared next time, if there is a next time. And we will find that the aftermath provides new opportunities, deepened relationships, and a different view of what it means to be part of a global community.

While you wait for the situation to change, be a force for good—a positive emotional contagion that infects everyone you encounter. By staying positive, calm, and healthy, you keep those around you calm and healthy, too.

If you have helpful advice to add to this post, please share it in a comment below. And share this post with anyone you feel might benefit.

Note: It’s important to stay informed about the state of coronavirus for the health and safety of your friends, family, and co-workers. Please visit the World Health Organization and the Center for Disease Control websites for up-to-date information. Also, be sure to check out your local health agencies and authorities for updates about your area.

source: https://ninaamir.com

pandemic

Staying Healthy During a Pandemic: 10 Immune-Boosting Tips

During the current coronavirus outbreak, you’re probably (very rightfully so!) concerned for your health and that of your family. The CDC has several recommendations for preventative action against coronavirus, including social distancing, hand-washing, and clean frequently touched surfaces daily.

We 100% agree with all of these recommendations, but additionally believe it’s prudent to do everything possible to boost your immune system to decrease the likelihood of getting sick (with coronavirus or any other seasonal bug, for that matter!)

Here are 10 easy ways you can help strengthen your immune system.

Eat immune-boosting foods.

Examples include: ginger, turmeric, honey, garlic, lemon, mushrooms, and bone broth.

Take immune-boosting supplements.

Try elderberry, zinc, vitamins A, C, and D, spirulina, and selenium.

Raise your core body temperature. Studies have found evidence that higher body temps help certain types of immune cells to work better, and thus make it better able to fight infection. Your body knows what it’s doing when you have a fever while sick! It’s thought that you can encourage the same benefits by proactively raising your body temp.

Try a sauna, steam bath, or move your body to break a sweat.

Get your veggies on: eating lots of veggies, especially leafy greens which are full of antioxidants, can help your body fight viruses and other free radicals.

The more diverse your diet (and especially veggie intake), the better!

Take antiviral supplements.

Some good ones include echinacea, colloidal silver, licorice root, apple cider vinegar, and probiotics.

Prioritize sleep: studies show that sleep can help build your immune system and fight infection.

Aim to get at least 7 hours of sleep a night. Need some help getting a good night of rest? Check out these tips!

Get your exercise on! Exercise has many great benefits and one of those is that it builds a stronger immune system.

The American Heart Association recommends at least 150 minutes of exercise a week – we say shoot for at least 20 minutes a day, every single day. Check out this 7-minute at-home workout that works – do it 3x for bonus points.

Ditch bad habits such as smoking and excessive drinking, as they can decrease ability to fight infection.

Reduce stress. The hormones released when you are stressed have been shown to have a negative effect on the immune system.

Try going for a walk, meditating, doing a YouTube yoga flow, or gratitude journaling.

Get some sunshine. A natural dose of vitamin D from the sun can do wonders not only for your mood but also your immune system – studies have shown that it can even decrease the length and severity of infections.

Go outside for at least 15-20 minutes a day even if it’s just on your patio or backyard.

Have any other immune-boosting best practices? We would love to hear them! Please share them at hello@cleanfitbox.com.

Stay healthy, friends!

March 17, 2020 by Rene

source: www.cleanfitbox.com

February 22, 2020
by misterpete4u Leave a comment

Vitamin Deficiencies Can Mess With Your Mental Health

There are mood-related signs you’re low on nutrients like vitamin D.
Here’s how to tell and what to do about it.

You’d be hard-pressed not to stumble on a social media #ad for vitamin packs. Trendy supplement brands like Ritual or Care/Of promise their products will help alleviate a series of vitamin deficiencies, which companies warn can cause health issues ― including problems with your mental health.

We know we need proper nutrients in order to function properly. But just how much of an impact do they really have on our minds?

“Optimal mental health requires adequate availability and absorption of vitamins, minerals and amino and fatty acids as essential building blocks for our brain cells and neurotransmitters,” said Dr. Jennifer Kraker, a New York-based psychiatrist who specializes in nutrition and mental health. “When our nutritional biochemistry is imbalanced, our mental health is affected.”

For most people, a healthy diet will take care of that. For others, a doctor may need to prescribe a vitamin supplement if the body doesn’t metabolize nutrients properly. (And they don’t have to come in an aesthetically pleasing glass bottle or Instagram-worthy capsule. Drug store brands will do just fine.)

“Because we’re all unique, one person may tolerate lower levels of a certain nutrient (such as vitamin D) very well, and another might not,” Kraker said. “Rinse and repeat for most all micronutrients.”

Nutritional deficiencies can tinker with your mental health on a sliding scale ― everything from mild to disruptive symptoms, depending on the person. Research has found certain deficiencies can contribute to anxiety and depression, as well as exacerbate symptoms in people with specific mental health disorders, such as obsessive compulsive disorder and bipolar disorder. A deficiency can also just slightly impact your emotional well-being.

“More commonly, nutrition-related issues are experienced as symptoms like reduced ability to manage stress, increased anxiety or edginess, lower mood, and poorer concentration or focus,” said Nicole Beurkens, licensed psychologist and board-certified nutrition specialist at Horizons Developmental Resource Center in Caledonia, Michigan.

Of course, mental health is complex and nutrients may be a minimal part of the puzzle (or sometimes they don’t influence it at all). That said, there are some cases where they play a role. There’s plenty that scientists are still working to discover and debunk about the food-mood connection and the impact that specific deficiencies can have on our mind, but here are some of the key nutritional players they’ve managed to suss out so far.

Vitamin D
This fat-soluble vitamin influences the expression of over 1,000 genes that regulate mood, sleep, as well as the protection and synthesis of neurons (the cells in our brain and nervous system that run the show).

There are vitamin D receptors throughout the body and brain, some of which are located in regions that influence mood, alertness, motivation, memory and pleasure.

“Vitamin D also regulates genes that make the feel-good brain chemicals serotonin and oxytocin,” Kraker said.

Symptoms of a vitamin D deficiency can include depression, anxiety, irritability and fatigue.

Vitamin B12
Besides helping with the formation of those ever-important neurons mentioned above, vitamin B12 plays a role in regulating mood-boosting brain chemicals like serotonin and dopamine, as well as stress hormones like norepinephrine.

“It also functions on a molecular level to aid in the detoxification of homocysteine, a neurotoxin for the brain that’s associated with depression,” Kraker said.

Symptoms of a vitamin B12 deficiency can include fatigue, brain fog, numbness and tingling, shortness of breath and more.

Vitamin B6

“Vitamin B6 concentrations are roughly 100 times higher in the brain than the body as a whole, implying importance in mental health function,” Kraker said. It’s a co-factor in making the brain’s feel-good chemicals, including serotonin, dopamine, and GABA.

And, like B12, vitamin B6 helps the body keep homocysteine levels in check, which helps with mood issues, Kraker said. People with kidney disease or malabsorption problems are the ones who are most likely to be deficient in B6.

Magnesium
In mental health, magnesium helps to regulate the stress response and is considered to be one of nature’s mood stabilizers, Kraker said.

It’s pretty uncommon to be deficient in magnesium, but it does happen. Symptoms that might indicate you’re low can include fatigue, nausea, loss of appetite and mood changes.

Zinc
Zinc is a trace mineral with many important roles in brain function, Kraker said. It also helps vitamin B6 do the best job possible of making feel-good chemicals like serotonin and dopamine.

Most people naturally get enough zinc through their diets. A deficiency can occur in women who are pregnant or breastfeeding, vegetarians and people with gastrointestinal disease. Symptoms can include loss of appetite or taste, loss of temper, depression and learning difficulties.

Iron
Besides regulating oxygen delivery throughout the body and brain, iron helps to create and balance mood-regulating chemicals like serotonin and dopamine.

“Those most at risk for an iron deficiency are fertile women, the elderly, and vegans who aren’t particularly mindful about how to eat to prevent an iron deficiency,” Kraker said.

Symptoms of an iron deficiency can include fatigue, difficulty concentrating and dizziness.

Omega-3 Fatty Acids
Omega-3s contain components called DHA and EPA, both of which play an important role in brain function: “They ward off inflammation, maintain brain cell health, and improve communication between brain cells,” Kraker said. They can also help with mood.

Symptoms of an omega-3 deficiency can include mood issues, often accompanied by dry skin, fatigue, allergies and chronic thirst.

How To Figure Out If You Have A Deficiency — And What To Do About It
Before we go any further, one important note we want to reiterate: This all isn’t to say overhauling your diet or taking vitamin supplements on your own will completely cure any mood-related symptoms. Other interventions like talk therapy and medication are the best-known ways to improve mental health issues.

You should look at nutrition as “an important adjunctive treatment to maintain health and prevent relapse, or use lower doses of pharmaceutical interventions,” Kraker said.

There are several physical signs that can clue you into whether there’s a potential deficiency brewing, Beurkens said. These can include frequent headaches, GI symptoms (think: constipation, diarrhea, gas and bloating), weak nails, dry skin or eczema, hair loss and many others.

“High stress levels also often accompany … symptoms and can negatively impact nutrient levels,” Beurkens added.

Similarly, adjusting to a new set of life stressors can impact how you take care of yourself and deplete nutrient stores in the process ― say, a recent move has you eating differently, a new job has upended your go-to lunch habits, or a newly diagnosed autoimmune condition has you adjusting to a whole new way of functioning.

Getting a comprehensive workup of your nutritional status can be helpful in getting to the root cause of what’s going on.

“Physical and mental health are interconnected, so nutrition should always be a part of the discussion when mental health symptoms are raised as a concern,” Beurkens said. “Unfortunately, this rarely happens.”

Start by opening up to your physician or psychiatrist about your suspicions: Share with them the symptoms you’re experiencing, a highlight reel of what your eating habits are like, and anything else you feel might be relevant, such as relatives who have the same deficiency.

Ask your doctor to either order relevant bloodwork that’s consistent with your symptoms or refer you to someone who specializes in both mental health and nutrition. (The Institute for Functional Medicine, Integrative Medicine for Mental Health, and the Walsh Research Institute all list doctors trained in this manner.)

“You know your body and your life best, so if something feels off, it probably is,” Kraker said.

With the right treatment plan ― which can include input from your doctor along with a psychologist or psychiatrist ― you’ll hopefully find a solution that works best for you.

By Krissy Brady 02/17/2020

source: www.huffingtonpost.ca

Magnesium May Improve Memory

Only 32% of Americans Get Recommended Daily Allowance of Magnesium, Researchers Say

Having trouble remembering where you left your keys? Forgot the name of an acquaintance?

A new study suggests that increasing your intake of magnesium, an essential mineral found in dark leafy vegetables and certain fruits, beans, and nuts, may help combat memory lapses associated with aging.

In the study, published Jan. 28 in Neuron, neuroscientists from the Massachusetts Institute of Technology (MIT) and Tsinghua University in Beijing found that increasing brain magnesium using a newly developed compound, magnesium-L-threonate (MgT), improves learning abilities, working memory, and short- and-long-term memory in rats. The magnesium also helped older rats perform better on a battery of learning tests.

“This study not only highlights the importance of a diet with sufficient daily magnesium, but also suggests the usefulness of magnesium-based treatments for aging-associated memory decline,” one of the study’s authors, Susumu Tonegawa, says in a news release. Tonegawa works at MIT’s Picower Institute for Learning and Memory.

Although the experiments were conducted in rats, the results have implications for humans, the researchers say.

Half of the population of the industrialized world has a magnesium deficiency, researcher Guosong Liu says in the release. “If MgT is shown to be safe and effective in humans, these results may have a significant impact on public health.”

Liu and his colleagues at MIT developed MgT after discovering in 2004 that magnesium might enhance learning and memory. Liu is co-founder of Magceutics, a California-based company that develops drugs for the prevention and treatment of age-related memory decline and Alzheimer’s disease.

Magnesium for Better Memory

The researchers examined how MgT stimulates changes in synapses, the junctions between neurons that are important in transmitting nerve signals.

They found that in young and old rats, MgT increased plasticity, or strength, among synapses and promoted the density of synapses in the hippocampus, a part of the brain that plays important roles in spatial navigation and long-term memory.

Other experiments performed within the study found that MgT treatment boosted memory recall under partial information conditions in older rats but had no effect in young rats. Aging causes dramatic declines in the ability to recollect memories when incomplete information is provided, the authors write.

“Because [magnesium] is an essential ion for normal cellular functions and body health, many physiological functions are impaired with the reduction of body [magnesium],” they write. The researchers cite that only 32% of Americans get the recommended daily allowance of magnesium.

The researchers conclude that the study provides “evidence for a possible causal relationship between high [magnesium] intake and memory enhancements in aged rats.” They also call for further studies to investigate the relationship between dietary magnesium intake, body and brain magnesium levels, and cognitive skills.

The recommended dietary allowance for magnesium for adults 19-30 years old is 400 milligrams/day for men and 310 milligrams/day for non-pregnant women. For adults 31 and older, it is 420 milligrams/day for men and 320 milligrams/day for non-pregnant women.

By Joanna Broder FROM THE WEBMD ARCHIVES

WebMD Health News Reviewed by Louise Chang, MD January 27, 2010

Magnesium for Depression

A controlled study of magnesium shows clinically significant improvement.

Magnesium is one of the most important minerals in the body. Years ago, I wrote about the importance of magnesium for the brain; it remains my most read blog post to this day.

We get most of our magnesium from plants (almonds, black beans, cashews, pumpkin seeds, and dark chocolate are all good sources), but it’s the bacteria in the soils that enable plants to absorb magnesium, so all sorts of environmental influences can deplete magnesium in our food, from pesticides that kill off bacteria to potassium-based fertilizers (can be taken up by plants in lieu of magnesium and calcium). Food processing, antacids, diuretics, caffeine, and alcohol can also decrease magnesium absorption. For these reasons, the modern human tends to need more magnesium and get less, leaving a lot of people chronically depleted. Blood levels remain fairly stable, because without magnesium in a narrow range, the heart can stop beating…every ICU doctor checks magnesium levels on patients pretty much every day, and repletes magnesium levels by the bag full to keep up with a patients’ needs under such intense stress as a critical illness.

Increased stress increases magnesium loss (as described here), and the environment may not readily replace it. Since magnesium is such an important mineral to the brain as a part of almost every part of the stress response, recovery, and repair, it seems self-evident to study magnesium as how it relates to brain function and common stress-related ailments such as clinical depression. Small studies have been found to be helpful for folks with fibromyalgia and major depression and type II diabetes. However, most of the studies that have been done are, admittedly, terrible.

The major flaw in most studies is they used insufficient amounts of magnesium oxide. On the face of it, magnesium oxide is about 60% elemental magnesium, which sounds pretty good. However, it is also a very stable compound, so often doesn’t disassociate into the parent compounds and give you the free magnesium you need.

Therefore, out of a 250mg tablet, you might only absorb 6mg. Magnesium malate is only 6.5% magnesium, but almost all of that is available to be absorbed. Magnesium citrate is also highly absorbable and 16% bioavailable. However, it is more likely than the other formulations to cause diarrhea. For a recent and much improved clinical trial of magnesium for depression, the researchers decided to use magnesium chloride.

The full text of the paper is free online at PLOS One. First the flaws: it was not double blinded, placebo controlled. Folks knew whether they were taking magnesium or not. However, the researchers did employ a crossover design as a control. In the first weeks of the study, half the patients took magnesium chloride (12% elemental magnesium and pretty much 100% bioavailable), and then in the second phase of the study, the first half was switched off magnesium while the other half of the patients took the supplement. The study wasn’t huge, but it wasn’t small either, with 126 depressed participants. The scale used to measure depression is my personal favorite, the PHQ9, and the average score was just over 10, which corresponds to a moderate depression. Some patients were on meds, others in therapy, some in neither, but the main key is that other treatments for depression did not change in the course of the study…magnesium chloride was added.

Participants were given 2000mg (248mg of elemental magnesium) daily for 6 weeks on an immediate or delayed (until week 7, the crossover) schedule. Depression scores on average over the trial dropped by 6 points, which brought the mean from moderately depressed to mild or minimally depressed, a clinically important change. Anxiety scores also improved. Participants reported reduced muscle cramps, aches and pains, constipation, and decreased headaches during the magnesium trial (all of these are known already to improve with magnesium supplementation and are signs of magnesium depletion). When asked after the trial if they would continue magnesium, over 60% said yes. Those that didn’t complained that magnesium didn’t help or it caused diarrhea (n = 8).

The positive effect of magnesium supplementation was gone within 2 weeks of stopping the supplement, indicating a relatively quick clearance.

Important notes:

Although the association between magnesium and depression is well documented, the mechanism is unknown. However, magnesium plays a role in many of the pathways, enzymes, hormones, and neurotransmitters involved in mood regulation. It is a calcium antagonist and voltage-dependent blocker of the N-methyl-D-aspartate channel which regulates the flow of calcium into the neuron. In low magnesium states, high levels of calcium and glutamate may deregulate synaptic function, resulting in depression. Depression and magnesium are also both associated with systemic inflammation. The finding that those participants taking an SSRI experienced an even greater positive effect points toward magnesium’s possible role in augmenting the effect of antidepressants.

So…it would have been nice to have a blinded study. However, magnesium supplementation is both inexpensive and pretty safe. The amount of magnesium in this trial was below the recommended daily allowance of elemental magnesium, and as long as you have normal kidneys, it’s difficult to take too much (diarrhea tends to limit outrageous usage). Magnesium can interfere with some medications and vice-versa, so check my old post for that info. For depression and constipation or headaches or restless legs or fibromyalgia, it makes sense to at least try magnesium for a few weeks. Those who prefer not to supplement can be encouraged to add nuts, seeds, and dark chocolate (a palatable and healthy prescription).

In the meantime, keep an eye on PubMed, because the studies are (slowly) getting better!

Emily Deans MD Jan 28, 2018

source: www.psychologytoday.com

December 7, 2019
by misterpete4u Leave a comment

2 Supplements That Prevent Heart Disease And Cancer

The most recent trial confirms that two nutrients can reduce deaths from heart attacks and cancer.

Omega-3 fatty acids from fish oil can significantly reduce heart attacks and vitamin D supplementation can significantly lower the number of deaths caused by different types of cancer.

Researchers studied 26,000 American adults in the VITAL clinical trial for five years to see if fish oil or vitamin D would definitely ward off cardiovascular disease or cancer.

The outcomes were reassuring: marine omega-3 fatty acid intake was linked to a significant drop in heart attacks.

One-and-half servings per week of dietary fish intake showed the maximum heart health benefits, but higher dietary fish intake didn’t help more.

The greatest decrease in heart attacks was seen in African-Americans.

The benefit of 1 gram of omega-3 fish oil supplementation showed a small decrease in major cardiovascular events like stroke and death from cardiovascular disease.

Vitamin D3 or cholecalciferol intake at a dose of 2000 IU per day showed a significant decrease of death from cancer for those who took it for at least two years.

However, supplementation with vitamin D3 capsules didn’t significantly lower incidence of any type of cancer or cardiovascular disease.

Dr. JoAnn Manson, the study’s first author, said:

“The pattern of findings suggests a complex balance of benefits and risks for each intervention and points to the need for additional research to determine which individuals may be most likely to derive a net benefit from these supplements.”

Dr. Stephanie Faubion, NAMS medical director, said:

“With heart disease and cancer representing the most significant health threats to women, it is imperative that we continue to study the viability of options that prevent these diseases and help women survive them.”

The 1 gram omega-3 fish oil supplementation used in the VITAL clinical trial was Omacor, a prescription medicine for adults.

The capsule contains 840 milligrams marine omega-3 fatty acids, of which 465 mg is eicosapentaenoic acid (EPA) and 375 mg is docosahexaenoic acid (DHA).

About the author
Mina Dean is a Nutritionist and Food Scientist. She holds a BSc in Human Nutrition and an MSc in Food Science.

The study was presented at the North American Menopause Society (NAMS) Annual Meeting in Chicago (Manson et al., 2019).

source: PsyBlog

2 Supplements That Double Weight Loss

Many overweight people are deficient in this essential nutrients.

A vitamin D supplement combined with calcium supplementation can help weight loss, research suggests.

People in the study who took vitamin D and calcium supplements lost more belly fat and experienced greater loss of fat mass.

One study has shown that people drinking more milk, which contains vitamin D and calcium, can double weight loss.

Up to half the world’s population may be deficient in vitamin D.

A deficiency in vitamin D could help to increase people’s appetite, research suggests.

Foods that are rich in vitamin D include oily fish and eggs, but most people get their vitamin D from the action of sunlight on the skin.

Around half of people who are obese have a calcium deficiency.

The body cannot produce calcium, so relies on it from food intake.

Foods high in calcium include dairy products, seeds, nuts and dark, leafy greens like spinach and kale.

The study included 53 overweight or obese people.

They were split into two groups with one put on an energy-restricted diet, that included 500 calories per day less than required.

The rest were put on the same diet, but also given calcium and vitamin D supplements.

The calcium supplement was 600 mg, while the vitamin D3 supplement was 125 IU.

The results showed that people taking calcium and vitamin D together lost 6 pounds of fat, while those in the comparison group only lost 4 pounds of fat.

The study’s authors write:

“Calcium plus vitamin D3 supplementation for 12 weeks augmented body fat and visceral fat loss in very-low calcium consumers during energy restriction.”

Although the exact mechanism for how calcium and vitamin D aid weight loss is not known, the authors speculate:

“The greater decrease in fat mass observed in the calcium+D group of the current study could result from several factors attributing to calcium metabolism.

First, a calcium-rich diet is shown to increase fat oxidation, promote fat cell apoptosis, and reduce lipid absorption due to the formation of insoluble calcium-fatty acid soaps in the intestine, which are eventually excreted in the feces.

Second, high dietary calcium intake is associated with suppression of 1,25-dihydroxyvitamin D (1,25-(OH)2D) levels which in turn act to decrease calcium influx into the cell.”

About the author
Psychologist, Jeremy Dean, PhD is the founder and author of PsyBlog. He holds a doctorate in psychology from University College London and two other advanced degrees in psychology.

He has been writing about scientific research on PsyBlog since 2004. He is also the author of the book “Making Habits, Breaking Habits” (Da Capo, 2003).

The study was published in the Nutrition Journal (Zhu et al., 2019).

source: Psyblog

November 10, 2018
by misterpete4u 4 Comments

Four Nutrients You Probably Need More Of

Chances are, you need to boost your intake of at least one or two nutrients. Even the most disciplined eaters can be, unknowingly, skipping out on key essentials, which can eventually drain energy and lead to health problems.

According to Health Canada’s Canadian Community Health Survey (CCHS), conducted in 2004, many people’s diets don’t provide enough vitamins and minerals. (Results from the 2015 CCHS have yet to be released.)

Haphazard eating and an increased reliance on heavily processed foods can undermine your diet.

Certain eating plans can also shortchange your body of nutrients.

A low-carbohydrate diet (e.g., ketogenic, Atkins-style) can deprive you of gut-friendly fibre, vitamin C and folate, a B-vitamin that repairs DNA in cells. Gluten-free diets can lack fibre and folate, too.

Even if you do eat the recommended amounts of vitamins and minerals, you might need more. Aging and certain medications can interfere with nutrient absorption.

Sure, you can take a supplement to bridge nutrient gaps. And, in some cases, I recommend that you do.

Adding whole foods to your diet, though, should be your first line of defence. Along with vitamins and minerals, whole foods deliver fibre, antioxidants and anti-inflammatory phytochemicals.

Nutrients to pay attention to

Vitamin A

It’s necessary for normal vision and immune function. Yet, according to Health Canada, more than one-third of Canadians don’t consume enough.

There are two types of vitamin A in foods: retinol, ready for the body to use, and carotenoids, which are converted to vitamin A in the body. Foods high in retinol include beef, pork, lamb, chicken, turkey, tuna, milk and cheese.

It’s carotenoids, though, that many people need more of. In addition to providing vitamin A, research suggests that a higher intake can help guard against heart attack, stroke and certain cancers.

Outstanding sources include sweet potato, carrots, pumpkin, spinach, collards, kale, dandelion greens and cantaloupe. You’ll absorb more carotenoids if you eat your meal with a little fat.

Vitamin B12

As many as 35 per cent of Canadian adults don’t consume the daily recommended 2.4 mcg of B12, a nutrient needed to make red blood cells, repair DNA and keep our nerves working properly.

B12 is found primarily in animal foods – meat, poultry, fish, eggs and dairy products. Some foods are fortified with B12, including plant-based “milks” (1 mcg per cup) and soy products. Fortified nutritional yeast, sold in natural-food stores, is also high in B12.

If you’re over 50, you might be getting less B12 than you realize. The absorption of B12 from foods relies on an adequate release of stomach acid. As many as 30 per cent of older adults have atrophic gastritis, a condition that reduces the stomach’s ability to release acid.

Proton pump inhibitors (PPIs), drugs used to treat ulcers and gastroesophageal reflux disease, interfere with B12 absorption by reducing stomach acid. Metformin, a medication that controls blood sugar, also reduces B12 absorption.

Older adults, vegans and people taking PPIs and metformin long-term should take multivitamin or B-complex supplements to ensure they’re meeting daily B12 requirements.

Vitamin C

More than one-third of our diets fall short of vitamin C, used to make collagen, help the immune system work properly and enhance iron absorption from plant foods. Vitamin C is also a powerful antioxidant, protecting cells from free radical damage.

The recommended daily intake is 75 mg (women) and 90 mg (men). (Smokers need an extra 35 mg.)
Include at least two vitamin C-rich foods in your daily diet such as red and green bell peppers (152 mg and 95 mg per ½ medium, respectively), oranges (70 mg per 1 medium), kiwifruit (64 mg each), strawberries (98 mg per cup), cantaloupe, broccoli, cauliflower and tomato juice.

To prevent chronic disease, some experts recommend a daily intake of 200 mg, an amount you can get by eating at least 5 daily servings (2.5 cups) of fruits and vegetables.

Magnesium

As many as 4 out of 10 Canadians consume too little magnesium, a mineral that helps regulate blood pressure, blood sugar and muscle and nerve function. That’s likely because some of the very best sources – pulses, leafy greens, bran cereal – are not everyday foods for many people.

Eating a diet high in magnesium is also tied to a lower risk of type 2 diabetes, stroke and colon cancer.

Adults need 310-320 mg (women) and 400-420 mg (men) each day. Excellent sources include oat bran, brown rice, quinoa, spinach, Swiss chard, hemp seeds, pumpkin seeds, almonds, cashews, black beans, lentils, tofu and edamame.

People who are likely to take a proton pump inhibitor long-term should take a daily magnesium supplement (200 to 250 mg) in addition to eating magnesium-rich foods.

Leslie Beck, a Toronto-based private practice dietitian, is Director of Food and Nutrition at Medcan.

November 4, 2018 Leslie Beck

Special to The Globe and Mail

October 11, 2017
by misterpete4u 2 Comments

Boost Bacteria to Bolster Your Brain

How can boosting bacteria in your body improve your brain health? Called the “second brain” by leading scientists, a healthy balance of flora in the gut helps to determine whether you’ll have a great memory and a strong resistance to brain disease.

And what happens in the gut plays a significant role in your brain health. Restoring beneficial bacteria and some healthy yeasts in your intestines (yes, some yeasts are beneficial, just not the ones that cause yeast infections) can go a long way toward protecting your mental faculties and preventing brain diseases altogether.

Frequently when I tell people about this connection between intestinal and brain health—what is known as the gut-brain axis, they tell me that they are covered because they eat yogurt on a regular basis. While yogurt may (or may not) help boost intestinal flora depending on whether it contains any live cultures at all, we need to give our guts a lot more than yogurt to help us establish a strong and healthy brain for life.

Let’s explore some of the exciting research into the link between beneficial microbes in our gut and our overall brain health.

Some probiotics actually function as antioxidants within the body, which can not only reduce the effects of free radical damage and aging, it is especially good news in the prevention and treatment of brain diseases.

That’s because the brain is vulnerable to free radical damage. Additionally, research at the University of California at Los Angeles (UCLA) found that consuming certain strains of probiotics could actually produce many brain health benefits, including improved sensory and emotional processing.

Since the brain plays a significant role in whether we suffer from mental health conditions like anxiety and depression, probiotics may also be helpful in addressing these serious health concerns. In animal studies conducted by the Department of Medicine at McMaster University, Hamilton, Ontario, Canada, and published in the medical journal Gastroenterology, the probiotic Bifidobacterium longum eliminated anxiety and normalized behavior. It appeared to work by reducing the excitability of the nerves in the gut that connect through the vagus nerve to the central nervous system, and in doing so, eliminated anxiety.

Hungarian researchers found that intestinal inflammation is one of the key factors involved in depression and that treating the inflammation with probiotics (along with B complex vitamins, vitamin D, and omega 3 fatty acids) reduced depressive symptoms.

Additional French research demonstrates the power of boosting specific strains of probiotics to boost mood and psychological health. They found that healthy study participants experienced reduced psychological stress, depression, anxiety, and anger and hostility, as well as improved problem-solving skills when taking the Lactobacillus helveticus and Bifidobacterium longum for 30 days.

While you can still enjoy yogurt if you are already doing so, please keep in mind that the above strains are not typically found in yogurt. I’m not aware of any yogurt that contains the best brain-boosting strains.

Take a probiotic supplement containing proven strains of brain-boosting probiotics such as Lactobacillus plantarum, Bifidobacterium longum, and Lactobacillus helveticus on a daily basis. Store your probiotics in the refrigerator, and take them on an empty stomach. First thing in the morning with a large glass of water tends to work well for most people.

Additionally, kimchi—the national dish of Korea which is typically a fermented mixture of cabbage, chilis, and garlic—frequently contains a much more diverse group of beneficial microbes than yogurt, making it an excellent choice as a brain boosting food. Some types contain fish sauce so if you’re vegan be sure to choose a fish sauce-free option. It is delicious on sandwiches, over brown rice, or as a side-dish to many foods. Be sure to choose kimchi that hasn’t been pasteurized to ensure the cultures are still intact.

By: Michelle Schoffro Cook October 5, 2017

source: www.care2.com

August 8, 2017
by misterpete4u 2 Comments

The Dangers Of Dietary And Nutritional Supplements Investigated

What you don’t know about these 12 ingredients could hurt you

We North Americans do love our dietary supplements. More than half of the adult population have taken them to stay healthy, lose weight, gain an edge in sports or in the bedroom, and avoid using prescription drugs. In 2009, we spent $26.7 billion on them, according to the Nutrition Business Journal, a trade publication.

What consumers might not realize, though, is that supplement manufacturers routinely, and legally, sell their products without first having to demonstrate that they are safe and effective. The Food and Drug Administration has not made full use of even the meager authority granted it by the industry-friendly 1994 Dietary Supplement Health and Education Act (DSHEA).

As a result, the supplement marketplace is not as safe as it should be.

We have identified a dozen supplement ingredients that we think consumers should avoid because of health risks, including cardiovascular, liver, and kidney problems. We found products with those ingredients readily available in stores and online.
Because of inadequate quality control and inspection, supplements contaminated with heavy metals, pesticides, or prescription drugs have been sold to unsuspecting consumers. And FDA rules covering manufacturing quality don’t apply to the companies that supply herbs, vitamins, and other raw ingredients.
China, which has repeatedly been caught exporting contaminated products, is a major supplier of raw supplement ingredients. The FDA has yet to inspect a single factory there.

The lack of oversight leaves consumers like John Coolidge, 55, of Signal Mountain, Tenn., vulnerable. He started taking a supplement called Total Body Formula to improve his general health. But instead, he says, beginning in February 2008, he experienced one symptom after another: diarrhea, joint pain, hair loss, lung problems, and fingernails and toenails that fell off. “It just tore me up,” he said.

Eventually, hundreds of other reports of adverse reactions to the product came to the attention of the FDA, which inspected the manufacturer’s facilities and tested the contents of the products. Most of the samples contained more than 200 times the labeled amount of selenium and up to 17 times the recommended intake of chromium, according to the FDA.

In March 2008 the distributor voluntarily recalled the products involved. Coolidge is suing multiple companies for compensatory damages; they have denied the claims in court papers. His nails and hair have grown back, but he said he still suffers from serious breathing problems.

The dirty dozen

Working with experts from the Natural Medicines Comprehensive Database, an independent research group, we identified a group of ingredients (out of nearly 1,100 in the database) linked to serious adverse events by clinical research or case reports. To come up with our dozen finalists, we also considered factors such as whether the ingredients were effective for their purported uses and how readily available they were to consumers. We then shopped for them online and in stores near our Yonkers, N.Y., headquarters and easily found all of them for sale in June 2010.

The dozen are aconite, bitter orange, chaparral, colloidal silver, coltsfoot, comfrey, country mallow, germanium, greater celandine, kava, lobelia, and yohimbe. The FDA has warned about at least eight of them, some as long ago as 1993.

Why are they still for sale? Two national retailers we contacted about specific supplements said they carried them because the FDA has not banned them. The agency has “the authority to immediately remove them from the market, and we would follow the FDA recommendation,” said a spokeswoman for the Vitamin Shoppe chain.

Most of the products we bought had warning labels, but not all did. A bottle of silver we purchased was labeled “perfectly safe,” with an asterisked note that said the FDA had not evaluated the claim. In fact, the FDA issued a consumer advisory about silver (including colloidal silver) in 2009, with good reason: Sold for its supposed immune system “support,” it can permanently turn skin bluish-gray.

Janis Dowd, 56, of Bartlesville, Okla., says she started taking colloidal silver in 2000 after reading online that it would keep her Lyme disease from returning. She says her skin changed color so gradually that she didn’t notice, but others did. “They kept saying, ‘You look a little blue.'”

Laser treatments have erased almost all the discoloration from Dowd’s face and neck, but she said it’s not feasible to treat the rest of her body.

Under the Dietary Supplement Health and Education Act (DSHEA), it is difficult for the FDA to put together strong enough evidence to order products off the market. To date, it has banned only one ingredient, ephedrine alkaloids. That effort dragged on for a decade, during which ephedra weight-loss products were implicated in thousands of adverse events, including deaths. Instead of attempting any more outright bans, the agency issued warnings, detained imported products, and asked companies to recall products it considered unsafe.

No scientific backup required

Of the more than 54,000 dietary supplement products in the Natural Medicines Comprehensive Database, only about a third have some level of safety and effectiveness that is supported by scientific evidence, according to a review by NMCD experts. And close to 12 percent have been linked to safety concerns or problems with product quality.

Consider the path to market of Go Away Gray, a product that is claimed to “help stop your hair from turning gray.” Cathy Beggan, president of the supplement’s maker, Rise-N-Shine, based in New Jersey, said that her company has not had to provide product information to the FDA. Nor did it conduct any clinical trials of the supplement, which includes a natural enzyme called catalase, before putting it on sale. Beggan pointed us to a study by European researchers published in the July 2009 issue of the Federation of American Societies for Experimental Biology Journal. The study found that gray hair had lower-than-normal levels of catalase but did not prove that taking that enzyme by mouth would stop hair from turning gray. “We are working on getting an actual clinical trial going because the results have been so amazing, and it would just be good to have some concrete data behind it,” Beggan said.

Consumers in the dark about dangers

In March 2008, Marques Parke, 29, a plumber from Janesville, Wis., took a weight-loss supplement called Hydroxycut because he wanted to lose 5 pounds, he said. Within weeks he was stricken with acute hepatitis and jaundice. He is suing the manufacturer and others. An attorney representing the defendants said they intended to contest the claims.

The FDA had received its first adverse-event report about Hydroxycut in 2002, long before Parke started taking it. In May 2009, by which point Parke’s liver was already damaged, the agency warned consumers to stop using Hydroxycut, and the manufacturer, Iovate Health Sciences, voluntarily recalled some of its products, its attorney said.

The company had frequently reformulated the product, according to the FDA, which said it didn’t know which ingredients produced the liver toxicity. The FDA said that Hydroxycut presented “a severe, potentially life-threatening hazard to some users” and had been linked to two reported deaths. Hydroxycut has been reformulated and is on the market again. An FDA representative told us the agency considers the new version acceptable.

Amazingly, for the first 13 years after the enactment of the Dietary Supplement Health and Education Act (DSHEA), supplement makers didn’t have to inform the FDA if they received reports of serious adverse events, an obligation that’s required for prescription drugs. A law that took effect in December 2007 closed that loophole, and in 2008 and 2009 the FDA said it received 1,359 reports of serious adverse effects from manufacturers and 602 from consumers and health professionals. But even with the new law, consumers can’t easily find out which products are involved because the FDA doesn’t routinely make those reports available to the public.

Exaggerated claims

It’s against the law for companies to claim that any supplement can prevent, treat, or cure any disease except some nutrient-deficiency conditions. But in the past two years, the Federal Trade Commission has filed or settled 30 cases against supplement marketers, charging that they made exactly those kinds of claims. It reached a $7.5 million settlement with the QVC home-shopping channel. And the FDA has recently taken legal action against a few supplement manufacturers that claimed their products could prevent or treat a disease.

Undercover investigators from the Government Accountability Office, posing as elderly consumers, caught salespeople on tape dispensing potentially harmful medical advice. In one case, a salesperson told an investigator that a garlic supplement could be taken in lieu of high blood pressure medicine.

What you can do

The FDA and Congress have recently taken some action to strengthen the agency’s oversight, such as passing a law requiring that companies report serious adverse events. But much more needs to be done to keep consumers safe. In the meantime, here are steps you can take to make sure the supplements you use are safe and beneficial.

Consult your doctor or pharmacist. Even helpful products can be harmful in some situations, such as when you’re pregnant or nursing, have a chronic disease, or are about to have elective surgery. And some supplements might be fine on their own but interact with certain prescription drugs. Your doctor or pharmacist can steer you away from such problems only if they know what supplements you’re taking or plan to take.

Beware of these categories. Supplements for weight loss, sexual enhancement, and bodybuilding have been problematic, the FDA said, because some contain steroids and prescription drugs. Lose weight through diet and exercise, get fit through training, and consult your doctor if you need help in the bedroom.

Look for the “USP Verified” mark. It indicates that the supplement manufacturer has voluntarily asked U.S. Pharmacopeia, a trusted nonprofit, private standards-setting authority, to verify the quality, purity, and potency of its raw ingredients or finished products. USP maintains a list of verified products on its website.

Don’t assume more is better. It’s possible to overdose even on beneficial vitamins and minerals. Avoid any product that is claimed to contain “megadoses.”

Report problems. Let your doctor know if you experience any symptoms after you start taking a supplement. And if you end up with a serious side effect, ask your doctor or pharmacist to report it to the FDA, or do it yourself at http://www.fda.gov/medwatch or by calling 800-332-1088.

Research in the right places. Be skeptical about claims made for supplements in ads, on TV, and by sales staff. If a claim sounds too good to be true, it probably is. Instead, try these sources:

The National Institutes of Health’s Office of Dietary Supplements.
The FDA, for alerts, advisories, and other actions.
Consumer Reports Health’s dietary supplements and natural health products information.

Your ‘all natural’ supplement might contain drugs

Consumers might be attracted to dietary supplements because they’re “all natural” and don’t contain the synthetic chemicals found in prescription drugs. But they might be getting fooled.

In the past two years, according to the Food and Drug Administration, manufacturers have voluntarily recalled more than 80 bodybuilding supplements that contained synthetic steroids or steroid-like substances, 50 sexual-enhancement products that contained sildenafil (Viagra) or other erectile-dysfunction drugs, and 40 weight-loss supplements containing sibutramine (Meridia) and other drugs.

Unwitting purchasers

“We’re talking about very serious risks and injuries that can happen to people—and often young people—who do not understand that they’re taking prescription drugs and steroids,” Joshua M. Sharfstein, M.D., the FDA’s principal deputy commissioner, told the U.S. Senate’s special committee on aging in May 2010.

In 2005, eager to make the most of his baseball scholarship at Lincoln University in Jefferson City, Mo., Jareem Gunter started taking a supplement he found online that promised to improve his athletic performance and claimed to be “legal,” he recalls. But he soon began feeling fatigued, and when the whites of his eyes turned yellow, he said, he went to the hospital. “I woke up in the morning and the doctor was sitting by my bedside,” Gunter said. “He told me, ‘Your liver’s failed. You only had a couple of days left to live if you hadn’t come in.'” The supplement turned out to contain a synthetic steroid, which cost Gunter his scholarship, he claimed in a lawsuit that was settled before the trial date, according to public court documents. He’s now 27 and living in Oakland, Calif. His health is much improved and he is working for a charitable organization and playing baseball in his hometown league.

Use with caution

Hazardous ingredients have been known to turn up in dietary supplements marketed for weight loss, bodybuilding, and sexual enhancement. And in light of the potentially serious health risks—including dangerous changes in blood pressure, serious liver injury, kidney failure, heart attack, and stroke—we think consumers should be extremely cautious with those categories of products or avoid them.

12 supplements you should avoid

These supplement ingredients are among those linked by clinical research or case reports to serious side effects. We worked with the Natural Medicines Comprehensive Database, an independent research group that evaluates the safety and effectiveness of nutritional supplements, to develop this list. We think it’s wise to avoid all the ingredients on it. Unless otherwise noted, there’s insufficient evidence to rate their effectiveness for their purported uses. Dangers listed are not meant to be all-inclusive.

Name (also known as)	Purported uses	Possible dangers	Comments
ACONITE (aconiti tuber, aconitum, radix aconiti)	Inflammation, joint pain, wounds, gout.	Toxicity, nausea, vomiting, low blood pressure, respiratory-system paralysis, heart-rhythm disorders, death.	Unsafe. Aconite is the most common cause of severe herbal poisoning in Hong Kong.
BITTER ORANGE (aurantii fructus, Citrus aurantium, zhi shi)	Weight loss, nasal congestion, allergies.	Fainting, heart-rhythm disorders, heart attack, stroke, death.	Possibly unsafe. Contains synephrine, which is similar to ephedrine, banned by the FDA in 2004. Risks might be higher when taken with herbs that contain caffeine.
CHAPARRAL (creosote bush, Larrea divaricata, larreastat)	Colds, weight loss, infections, inflammation, cancer, detoxification.	Liver damage, kidney problems.	Likely unsafe. The FDA advises people not to take chaparral.
COLLOIDAL SILVER (ionic silver, native silver, Silver in suspending agent)	Fungal and other infections, Lyme disease, rosacea, psoriasis, food poisoning, chronic fatigue syndrome, HIV/AIDS.	Bluish skin, mucous membrane discoloration, neurological problems, kidney damage.	Likely unsafe. The FDA advised consumers about the risk of discoloration on Oct. 6, 2009.
COLTSFOOT (coughwort, farfarae folium leaf, foalswort)	Cough, sore throat, laryngitis, bronchitis, asthma.	Liver damage, cancer.	Likely unsafe.
COMFREY (blackwort, common comfrey, slippery root)	Cough, heavy menstrual periods, chest pain, cancer.	Liver damage, cancer.	Likely unsafe. The FDA advised manufacturers to remove comfrey products from the market in July 2001.
COUNTRY MALLOW (heartleaf, Sida cordifolia, silky white mallow)	Nasal congestion, allergies, asthma, weight loss, bronchitis.	Heart attack, heart arrhythmia, stroke, death.	Likely unsafe. Possible dangers linked with its ephedrine alkaloids banned by the FDA in 2004.
GERMANIUM (Ge, Ge-132, germanium-132)	Pain, infections, glaucoma, liver problems, arthritis, osteoporosis, heart disease, HIV/AIDS, cancer.	Kidney damage, death.	Likely unsafe. The FDA warned in 1993 that it was linked to serious adverse events.
GREATER CELANDINE (celandine, chelidonii herba, Chelidonium majus)	Upset stomach, irritable bowel syndrome, liver disorders, detoxification, cancer.	Liver damage.	Possibly unsafe.
KAVA (awa, Piper methysticum, kava-kava)	Anxiety (possibly effective).	Liver damage.	Possibly unsafe. The FDA issued a warning to consumers in March 2002. Banned in Germany, Canada, and Switzerland.
LOBELIA (asthma weed, Lobelia inflata, pukeweed, vomit wort)	Coughing, bronchitis, asthma, smoking cessation (possibly ineffective).	Toxicity; overdose can cause fast heartbeat, very low blood pressure, coma, possibly death.	Likely unsafe. The FDA warned in 1993 that it was linked to serious adverse events.
YOHIMBE (yohimbine, Corynanthe yohimbi, Corynanthe johimbi)	Aphrodisiac, chest pain, diabetic complications, depression; erectile dysfunction (possibly effective).	Usual doses can cause high blood pressure, rapid heart rate; high doses can cause severe low blood pressure, heart problems, death.	Possibly unsafe for use without medical supervision because it contains a prescription drug, yohimbine. The FDA warned in 1993 that reports of serious adverse events were under investigation.

Clarification: Source: Natural Medicines Comprehensive Database, Professional Version, June 2010

11 supplements to consider

These popular supplements, listed in alphabetical order, have been shown to likely be safe for most people and possibly or likely to be effective in appropriate doses for certain conditions. Talk to your doctor or pharmacist before starting any supplement. Most supplements haven’t been studied in pregnant or nursing women. The list of interactions and side effects is not all-inclusive.

Name (also known as)	Efficacy for selected uses	Selected potential side effects	Selected drug interactions
CALCIUM (calcium carbonate, calcium citrate, calcium gluconate)	Likely effective in combination with vitamin D in preventing and treating bone loss and osteoporosis. Taken daily, appears to reduce some PMS symptoms.	Belching, gas.	Calcium can decrease the effectiveness of certain antibiotics, osteoporosis drugs, and thyroid drugs.
CRANBERRY (American cranberry, large cranberry, cranberry extract)	Possibly effective for preventing recurrent urinary-tract infections.	Large amounts can cause stomach upset, diarrhea.	Might increase the effects of the blood thinner warfarin.
FISH OIL (EPA/DHA, omega-3 fatty acids, PUFA)	Effective for reducing triglyceride levels. Likely effective for decreasing the risk of heart attack, stroke, and progression of hardening of the arteries in people with existing heart disease.	Fishy aftertaste, upset stomach, nausea, loose stools. High doses can increase levels of LDL (bad) cholesterol in some people or increase the chance of bleeding.	Might increase the effect of blood-thinning drugs and high blood pressure medications.
GLUCOSAMINE SULFATE (G6S, glucosamine sulfate 2KCl, glucosamine sulfate-potassium chloride)	Likely effective treatment for reducing symptoms of osteoarthritis of the knee. Might also help slow progression of osteoarthritis.	Nausea, heartburn, diarrhea, constipation, headache.	Might increase the blood-thinning effect of warfarin and cause bruising and bleeding.
LACTASE (beta-galactosidase)	Likely effective for reducing gastrointestinal symptoms in lactoseintolerant people when used before consuming lactose or when added to milk.	No reported side effects.	None known.
LACTOBACILLUS (acidophilus, acidophilus lactobacillus, probiotics)	Possibly effective for preventing diarrhea while taking antibiotics.	Gas. People with poor immune function should check with their doctor first.	Might cause infection in people taking immunosuppressant drugs.
PSYLLIUM (blond plantago, blonde psyllium, plantago, isabgola)	Effective as a bulk laxative for reducing constipation or softening stools. Likely effective for lowering cholesterol in people with mild to moderately high cholesterol.	Gas, stomach pain, diarrhea, constipation, nausea. Some people can have a serious allergic response that requires immediate medical attention.	Might decrease the effectiveness of carbamazepine, an antiseizure drug; digoxin, a heart drug; and lithium, for bipolar disorder. Might cause low blood sugar when taken with some diabetes drugs.
PYGEUM (African plum tree, African prune, Prunus africana)	Likely effective for reducing symptoms of an enlarged prostate.	Nausea, abdominal pain.	None known.
SAMe (ademetionine, adenosylmethionine, S-Adenosyl-L-Methionine, sammy)	Likely effective in reducing symptoms of major depression, reducing pain, and improving functioning in people with osteoarthritis.	GI symptoms, dry mouth, headache, mild insomnia, anorexia, sweating, dizziness, and nervousness, especially at higher doses. It can make some people with depression feel anxious.	Might lead to a toxic reaction when taken with the cough suppressant dextromethorphan, certain antidepressants, or narcotic pain relievers. Might worsen symptoms when taken with the Parkinson’s drug levodopa.
ST. JOHN’S WORT (Hypericum perforatum, Saynt Johannes Wort, SJW)	Likely effective for improving symptoms of some forms of depression.	Insomnia, vivid dreams, anxiety, dizziness, headache, skin rash, and tingling. It can cause skin to become extra-sensitive to the sun.	Can decrease the effectiveness of a wide range of drugs, including birth-control pills, heart medications, HIV/AIDS drugs, and warfarin. Might also increase the effects or side effects of certain antidepressants.
VITAMIN D (Cholecalciferol, vitamin D3, ergocalciferol, vitamin D2)	Likely effective when taken with calcium to help prevent osteoporosis. Might help reduce falls in people with vitamin D deficiency and bone loss in people taking corticosteroids.	Extremely large amounts might cause weakness, fatigue, headache, and nausea, though side effects are rare.	Might reduce the effectiveness of some medications, such as atorvastatin (Lipitor), other heart medications, birth-control pills, HIV/AIDS drugs.

Clarification: Source: Natural Medicines Comprehensive Database, Professional Version, June 2010

September 2010 source: www.consumerreports.org

July 20, 2017
by misterpete4u Leave a comment

This Mineral Fights Depression — And It Is Cheaper And Safer Than Drugs

The supplement starts to take effect after only two weeks, the researchers found.

Over-the-counter magnesium is a safe and effective way to treat mild to moderate depression, a new study suggests.

The mineral magnesium has already been linked to lower inflammation and improvements in depression.

Now a new randomised controlled trial has tested the effects of magnesium chloride supplements compared with no treatment.

For the research, half of 126 people with mild to moderate depression were given 248 mg of magnesium chloride per day for six weeks.

After just two weeks, some positive effects of the supplement could be seen.

Those taking magnesium had clinically significant improvements over the six weeks.

People did not have any problems taking magnesium and there were no differences based on sex, age, whether people were also taking antidepressants, or other factors.

More than half of the people in the study said they would continue to take magnesium to help them with their depression.

Ms Emily Tarleton, the study’s first author, said:

“This is the first randomized clinical trial looking at the effect of magnesium supplementation on symptoms of depression in U.S. adults.
The results are very encouraging, given the great need for additional treatment options for depression, and our finding that magnesium supplementation provides a safe, fast and inexpensive approach to controlling depressive symptoms.”

Ms Tarleton says that the next stage is to move on to larger populations to see if the results can be replicated.

While many more studies have investigated antidepressant medications, there is also much evidence of their side-effects.

A survey of people taking antidepressants has found higher than expected levels of emotional numbness, sexual problems and even suicidal thoughts associated with the medication.

Of the 20 adverse effects to antidepressants that people were questioned about:

62% said they had ‘sexual difficulties’,
52% said they ‘didn’t feel like themselves’,
42% noticed a ‘reduction in positive feelings’,
39% found themselves ‘caring less about others’,
and 55% reported ‘withdrawal effects’.

The study was published in the journal PLOS ONE (Tarleton et al., 2017).

JULY 12, 2017

source: PsyBlog

May 14, 2017
by misterpete4u Leave a comment

This Mineral May Be Key to Protecting Your Bones (It’s Not Calcium)

Calcium and vitamin D may get the spotlight when it comes to bone health, but there’s another mineral that plays a role in keeping your skeleton strong: It’s magnesium, and 67% of the body’s stores for this mineral are found in your bones. Now, research published in the European Journal of Epidemiology suggests magnesium could help prevent fractures.

While previous research had revealed that magnesium supports bone growth, no study had tied the mineral to risk of bone fractures. Tapping into over 20 years of data on 2,245 men, investigators in Britain and Finland compared the men’s magnesium blood levels to their risk of fracture. They discovered that the higher a man’s magnesium, the lower his risk of fracture.

Magnesium works with bone building cells (aka osteoblasts), and works in conjunction with vitamin D and parathyroid hormone to keep calcium levels normal, and fracture risk low. Medical factors affecting magnesium absorption include inflammatory bowel disease (or other chronic diarrhea problems), kidney insufficiency or certain medications.

So, how much magnesium should you eat? The recommended daily intake for adults over 31 years of age is 320 mg for females and 420 mg for males. Nuts and seeds, especially almonds, sunflower seeds, walnuts and cashews are rich in magnesium. Other food sources include oatmeal, milk, peanut butter, spinach, broccoli, peas and beets.

However, the Finnish study couldn’t link dietary intake of magnesium to higher blood levels of magnesium, which is strange. Although the study authors aren’t sure why food couldn’t boost levels, previous research suggests an improvement in bone density among menopausal women who took supplements of magnesium hydroxide.

The bottom line is that eating foods high in magnesium still makes sense, since those foods tend to be healthy. If you’re at elevated risk for osteoporosis or fracture talk to your physician or a registered dietitian about taking magnesium supplements.

BY JENNIFER BOWERS, PHD, RD

source: www.rd.com

Our Better Health

Diet, Health, Fitness, Lifestyle & Wellness

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Magnesium May Improve Memory

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The dirty dozen

No scientific backup required

Consumers in the dark about dangers

Exaggerated claims

What you can do

Your ‘all natural’ supplement might contain drugs

Unwitting purchasers

Use with caution

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