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The Simple Treatment That Beats Antidepressants

Two-thirds of people with major depression were no longer depressed after this treatment.

A brisk walk three times a week can actually beat antidepressant medication in treating major depression, research finds.

The results come from a study on three groups of elderly people with major depressive disorder.

One group were given the exercise, another given antidepressant medication and the third both.

The results showed that all three groups improved the same amount.

Professor James Blumenthal, the study’s first author, said:

“One of the conclusions we can draw from this is that exercise may be just as effective as medication and may be a better alternative for certain patients.”

The results showed that after exercise almost two-thirds of participants were no longer depressed after 16 weeks.

One of the problems with exercise is that it may take a little longer to take effect.

Professor Blumenthal said:

“While we don’t know why exercise confers such a benefit, this study shows that exercise should be considered as a credible form of treatment for these patients.
Almost one-third of depressed patients in general do not respond to medications, and for others, the medications can cause unwanted side effects.
Exercise should be considered a viable option.”

Exercise could be particularly beneficial because people are taking an active role, rather than passively taking a pill, Professor Blumenthal said:

“Simply taking a pill is very passive.
Patients who exercised may have felt a greater sense of mastery over their condition and gained a greater sense of accomplishment.
They felt more self-confident and had better self-esteem because they were able to do it themselves, and attributed their improvement to their ability to exercise.
These findings could change the way some depressed patients are treated, especially those who are not interested in taking anti-depressants.
While these medications have been proven to be effective, many people want to avoid the side effects or are looking for a more ‘natural’ way of feeling better.”

The antidepressant tested in the study was sertraline, which is marketed as Zoloft.

The study was published in the journal Archives of Internal Medicine (Blumenthal et al., 1999).

 source: PsyBlog


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The Natural Dietary Add-On Found To Treat Depression

64% of depression and anxiety patients saw reductions in their symptoms.

Probiotics relieve the symptoms of depression, as well as helping with digestion problems, a new study finds.

The research was carried out on people with irritable bowel syndrome who were also depressed.

Twice as many reported improvements in depression symptoms if they took a specific probiotic.

Dr Premysl Bercik, senior study author, said:

“This study shows that consumption of a specific probiotic can improve both gut symptoms and psychological issues in IBS.
This opens new avenues not only for the treatment of patients with functional bowel disorders but also for patients with primary psychiatric diseases.”

The probiotic is called Bifidobacterium longum NCC3001.

Half of the 44 adults with IBS and mild to moderate anxiety or depression took a daily dose.
Over 10 weeks those taking the probiotic showed improvements in their IBS and depression and anxiety.

64% of those taking the probiotics showed psychological improvements compared with just 32% in the placebo group.

Brain scans revealed changes in multiple brain areas related to mood control.

Dr Bercik said:

“This is the result of a decade long journey — from identifying the probiotic, testing it in preclinical models and investigating the pathways through which the signals from the gut reach the brain.”

The study’s first author, Dr. Maria Pinto Sanchez, added:

“The results of this pilot study are very promising but they have to be confirmed in a future, larger scale trial.”

Other studies have also shown that probiotics have promise in treating depression.

One mouse study in which they were fed Lactobacillus, found that the probiotic reversed  their depression.

Another study found that a multispecies probiotic helped stop sadness from turning into depression.

Recent studies have repeatedly underlined the importance of diet for how we feel.

The new study was published in the journal Gastroenterology (Pinto-Sanchez et al., 2017).

source: PsyBlog


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Probiotic Use Linked to Improved Symptoms of Depression

A new study is the first to show improved depression scores with a probiotic.
It adds to the whole field of microbiota-gut-brain axis,
providing evidence that bacteria affect behavior.

Probiotics may relieve symptoms of depression, as well as help gastrointestinal upset, research from McMaster University has found.

In a study published in the medical journal Gastroenterology, researchers of the Farncombe Family Digestive Health Research Institute found that twice as many adults with irritable bowel syndrome (IBS) reported improvements from co-existing depression when they took a specific probiotic than adults with IBS who took a placebo.

The study provides further evidence of the microbiota environment in the intestines being in direct communication with the brain said senior author Dr. Premysl Bercik, an associate professor of medicine at McMaster and a gastroenterologist for Hamilton Health Sciences.

“This study shows that consumption of a specific probiotic can improve both gut symptoms and psychological issues in IBS. This opens new avenues not only for the treatment of patients with functional bowel disorders but also for patients with primary psychiatric diseases,” he said.

IBS is the most common gastrointestinal disorder in the world, and is highly prevalent in Canada. It affects the large intestine and patients suffer from abdominal pain and altered bowel habits like diarrhea and constipation. They are also frequently affected by chronic anxiety or depression.

The pilot study involved 44 adults with IBS and mild to moderate anxiety or depression. They were followed for 10 weeks, as half took a daily dose of the probiotic Bifidobacterium longum NCC3001, while the others had a placebo.

At six weeks, 14 of 22, or 64%, of the patients taking the probiotic had decreased depression scores, compared to seven of 22 (or 32%) of patients given placebo.

Functional Magnetic Resonance Imaging (fMRI) showed that the improvement in depression scores was associated with changes in multiple brain areas involved in mood control.

“This is the result of a decade long journey — from identifying the probiotic, testing it in preclinical models and investigating the pathways through which the signals from the gut reach the brain,” said Bercik.
“The results of this pilot study are very promising but they have to be confirmed in a future, larger scale trial,” said Dr. Maria Pinto Sanchez, the first author and a McMaster clinical research fellow.

 

Materials provided by McMaster University.  Content may be edited for style and length.

Journal Reference:
Maria Ines Pinto-Sanchez, Geoffrey B. Hall, Kathy Ghajar, Andrea Nardelli, Carolina Bolino, Jennifer T. Lau, Francois-Pierre Martin, Ornella Cominetti, Christopher Welsh, Amber Rieder, Jenna Traynor, Caitlin Gregory, Giada De Palma, Marc Pigrau, Alexander C. Ford, Joseph Macri, Bernard Berner, Gabriela Bergonzelli, Michael G. Surette, Stephen M. Collins, Paul Moayyedi, Premysl Bercik. Probiotic Bifidobacterium longum NCC3001 Reduces Depression Scores and Alters Brain Activity: a Pilot Study in Patients With Irritable Bowel Syndrome. Gastroenterology, 2017; DOI: 10.1053/j.gastro.2017.05.003

ScienceDaily, 23 May 2017. 
 


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Experts Urge Huge Expansion of Online Therapy For Mental Illness

A “massive and growing” mental health burden across the world can only be tackled successfully with a major expansion of online psychiatric resources such as virtual clinics and web-based psychotherapies, specialists said on Tuesday.

With resources tight and the global mental health system only serving around 10 percent of patients even now, specialists speaking at the European Congress on Psychiatry (ECP) said the web is the only option for significant extra treatment capacity.

The World Health Organization (WHO) said last week mental disorders – in particular depression – are now the leading cause of ill health and disability worldwide.

Rates of depression have risen by more than 18 percent since 2005, the WHO says, and a lack of support for mental health combined with a common fear of stigma means many do not get the treatment they need. [L2N1H70MW]

Michael Krausz, a professor of psychiatry at the University of British Columbia in Canada, and a leading specialist at the World Psychiatric Association, said “E-mental health” should be a major part of the answer.

“Through a proactive approach we can create an additional virtual system of care which could build capacity, improve the quality of care and make mental health care more effective,” he told the ECP.

Web-based psychological treatments such as online cognitive behavior therapy (CBT) have proven effective in several conditions including depression and anxiety. Krausz said there is also potential for online CBT to be modified for conditions such as post-traumatic stress disorder (PTSD).

“Online assessments, web-based psychotherapies,… and online research strategies will significantly change the field,” he told the congress.

Technologies like virtual reality and artificial intelligence can also be used in certain therapies for anxiety, and various online games and apps are being developed to support treatment of depression in children.

In another example, scientists at King’s College London have developed an avatar-based system to help treat people with schizophrenia who hear distressing voices.

(Reporting by Kate Kelland,; Editing by Stephen Powell)         Mon Apr 3, 2017


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The Number 1 Cause of Ill Health Worldwide

Depression is the leading cause of disability and ill health worldwide.

There are over 300 million living with depression around the world.

This represents an increase of 18% between 2005 and 2015, according to figures put out by the World Health Organisation (WHO).

Almost 50% of people who are depressed do not get any treatment, even in high-income countries.

Two important reasons are:

  • Lack of support for people with mental health problems,
  • and stigma.

The WHO is currently running a year-long campaign called “Depression: let’s talk”.

Dr Shekhar Saxena, Director of the Department of Mental Health and Substance Abuse at WHO, said:

“The continuing stigma associated with mental illness was the reason why we decided to name our campaign ‘Depression: let’s talk’.
For someone living with depression, talking to a person they trust is often the first step towards treatment and recovery.”

Depression usually includes the following, lasting for two weeks or more:

  • loss of interest in activities that used to be enjoyed,
  • persistent sadness,
  • and problems with everyday activities.

Dr Saxena said:

“A better understanding of depression and how it can be treated, while essential, is just the beginning.
What needs to follow is sustained scale-up of mental health services accessible to everyone, even the most remote populations in the world.”

 

source: PsyBlog


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This Simple Realisation Linked To 80% Depression Recovery

Six months later, 80% had recovered from depression, researchers found.

Rumination — thinking about the causes and consequences of depressing events — is common in depression.

However, simply realising that you don’t have to ruminate can be liberating, new research suggests.

When people learned to reduce how much they ruminated, 80% had recovered after six months (including 10 weeks of therapy).

Professor Roger Hagen, who led the research, said:

“Anxiety and depression give rise to difficult and painful negative thoughts.
Many patients have thoughts of mistakes, past failures or other negative thoughts.
Metacognitive therapy addresses thinking processes.”
One of the problems in depression is that people…
“…think too much, which MCT [metacognitive therapy] refers to as ‘depressive rumination’.

Rather than ruminating so much on negative thoughts, MCT helps patients to reduce negative thought processes and get them under control.”

Taking control of your thoughts is an important part of modern cognitive therapies.

Professor Hagen said:

“Instead of reacting by repeatedly ruminating and thinking ‘how do I feel now?’ you can try to encounter your thoughts with what we call ‘detached mindfulness.’

You can see your thoughts as just thoughts, and not as a reflection of reality.
Most people think that when they think a thought, it must be true.
For example, if I think that I’m stupid, this means I must be stupid.
People strongly believe that their thoughts reflect reality.”

Many patients who took part in the study were pleasantly surprised, said Professor Hagen:

“The patients come in thinking they’re going to talk about all the problems they have and get to the bottom of it, but instead we try to find out how their mind and thinking processes work.
You can’t control what you think, but you can control how you respond to what you think.”

The study was published in the journal Frontiers in Psychology (Hagen et al., 2017).

 

MARCH 19, 2017
source: PsyBlog


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Beating Depression May Be All About Learning to Ignore Negative Thoughts

A promising type of therapy focuses on quitting the worry cycle.

People who struggle with anxiety or depression often ruminate on negative thoughts, like past missteps or feelings that they’re not good enough. The secret to better mental health may be learning how not to dwell on these thoughts, according to new research by a group of British and Norwegian researchers.

Their study focuses on a technique called metacognitive therapy, or MCT, which was developed in Europe in the 1990s. MCT trains people to lessen the ruminative process, says study co-author Stian Solem, PhD, associate professor of psychology at the Norwegian University of Science and Technology.

In the United States and Europe, the current recommended treatments for depression and anxiety are medications and cognitive behavioral therapy, or CBT. Sometimes called talk therapy, CBT encourages people to analyze their negative thoughts and challenge whether they’re really true.

That’s what makes MCT different: Instead of drilling deeper into those thoughts, MCT helps people reduce negative thought processes and take control over them, says Solem.

Solem and his colleagues tested the MCT method in 20 patients with depression, who attended 10 therapy sessions over a 10-week period. The study also involved a control group of 19 people who were wait-listed for MCT, and receive no treatment for the first 10 weeks.

After those 10 weeks, about 80% of patients in the MCT group reported a full recovery from depression symptoms, based on a standard screening questionnaire. Anxiety symptoms also improved overall, and no patients reported worsening of their condition. In comparison, only about 5% of patients in the control group had a similar recovery.

Six months after completing MCT, recovery rates were similar, with only a few patients reporting relapses. Studies on CBT have shown that only 40% to 48% of patients are recovered after treatment, the authors write, and between 40% and 60% relapse within two years.

For a lot of people, the authors say, realizing that they don’t have to worry and ruminate about things can be quite liberating. They say MCT patients are often pleasantly surprised that they didn’t have to rehash all of their problems in their therapy sessions.

Smaller studies at the University of Manchester, where MCT was developed, have also shown that this method can be effective at treating depression—but this is the first published study to involve a control group. This helps support the theory that improvements are really from the therapy, and not just symptoms getting better on their own over time.

The researchers say a soon-to-be-published Danish study also found similar results. They hope that, with these findings, MCT becomes more popular in Norway and around the world.

MCT has not yet caught on in the United States, says Solem, and no U.S. practitioners are included in the MCT Institute’s online database of registered therapists. (The MCT Institute is in the process of developing self-help materials, its website states, but these aren’t yet available.) However, Solem says that the principles of MCT can be helpful for most people, even without formal training.

“Many of our patients have conflicted beliefs concerning worry and rumination,” Solem told Health in an email. “They experience that it is uncontrollable, exhausting, and dangerous—‘I can go mad,’ ‘I can make myself sick.’” At the same time, they think they need to ruminate in order to find answers and prevent danger.

“In MCT we often start out with postponing worry and rumination (which most people are able to do) and later we use something called detached mindfulness,” he says. “It involves being aware of the trigger thought, but choosing not to engage in it.”

 By Amanda MacMillan       March 15, 2017