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Natural Remedies For The Most Nagging Everyday Ailments

Post-work headache, we will bear you no more.

Adaptation has its pros and cons. While we humans often benefit from melding into changing environments, we can also become accustomed to constant daily discomforts.
Whether it’s the after-work headache, a cough that you can’t seem to shake, eye strain, achy joints or chapped lips, it could be time to raise the bar of expectation, wave the kitchen spoon, and bear it no more.

For quick and easy remedies, here are some recipes and simple techniques that you can stir-up at home, to shake it all off.

Headaches

When it comes to headaches, we can investigate two major culprits: dehydration and elimination. If we are not properly hydrated or if we are constipated, we could be suffering from frequent headaches. A quick and easy solution is to drink room temperature water with a pinch of Himalayan salt to return trace minerals and hydration back into the body. If you are not eliminating properly, then you could place a warm castor oil pack on the stomach to help kick start excretion. Castor oil packs and Himalayan salt can be purchased at most natural health food stores.

Neck tension

Tension headaches can occur when we hold stress or strain in our shoulders, chest, neck or eyes. To relieve stress in the neck and shoulder areas, start by stretching open the arms and breathing deeply into the chest a few times. Release the arms to down. Open the jaw and stretch the chin down toward the chest. While holding this gesture, inhale and exhale through the mouth 3 times. Close the mouth and slowly and gently, begin to move the neck forward, then back to neutral. The motion should look as though you are a chicken, slowly pecking for food. The neck should not move backward, only forward to neutral. Repeat this action 15 to 20 times. This will release the tension in the neck.

Eye strain

Tired red eyes or eye strain can often accompany headaches at the end of a long day. Stretching your eyes can relieve stress and tension. Start by slowly looking up toward the forehead, then down towards your toes.  The eyes should feel like they are stretching up and down, as you move them. Then in a horizontal movement, slowly look all the way to the left and then all the way to the right. Remember not to move your neck or head. Move only the eyes. In a diagonal movement, look to the top right corner of the eyes, then look down to the bottom, left corner of the eyes. Finally, look up to the top left corner of the eyes, then down to the lower right corner of the eyes in a diagonal. Repeat very slowly, 8 times in each direction and then close the eyes for a moment.

Another exercise is ‘Blink 45’: Sitting down, blink rapidly 45 times in a row. This can also help to loosen tension and re-energize the eyes. To avoid dizziness, wait a few minutes before standing up.

Cold symptoms: Achy joints, runny nose and sore throat

Try these three remedies to relieve symptoms.

The gift of gold: Turmeric and honey

Turmeric is an immune modulator that acts as a natural anti-microbial with antibacterial and antiviral properties. It can also be used to reduce inflammation in the joints and increase immunity.

Mix a ¼ teaspoon of turmeric powder with a spoon of organic honey until it becomes a smooth golden paste. Lick the honey and turmeric mixture throughout the day.

Fresh, energizing ginger tea

Warm liquids increase the body’s temperature, which can help to maintain immunity and reduce stagnation in the joints.  Honey is antimicrobial and is packed with nourishing minerals. Ginger fights infection, improves digestion and reduces nausea.

Cut and peel a few round slices of fresh ginger. Pound the cut ginger with a mortar and pestle to release the juices. Add the juice and the pounded ginger slices to about two cups of water and bring it to a boil for a few minutes. Take it off the heat, and let it cool for a few minutes. Pour the tea into a thermos and sip it throughout the day.

Himalayan salt and lime

Although a simple salt gargle could suffice, a shot of Himalayan salt and lime can be a potent antibacterial concoction. Squeeze half of a lime and combine the fresh lime juice with two or three pinches of Himalayan salt. Mix together and sip slowly.

Chapped lips

A fast and easy remedy can be found at the centre of your universe – the navel. Before bed, lie down and place a few drops of warm, natural oil into the navel. Allow the navel to retain the oil for about 1 minute before rubbing it in. *Natural options for oil are cold-pressed sesame, sunflower, almond or coconut oils.

Nicole Mahabir · CBC Life · November 15

Nicole Mahabir is the Founder and Director of JAI Wellness, a platform for health education, mindful living and wellbeing. For the past 10 years, Nicole has lead professional certified programs, teaching Nutrition, Meditation, Ayurveda, Yoga Therapy and Natural Anti-Ageing Beauty Regimes. When she isn’t teaching, Nicole creates integrated, sustainable health protocols for her busy clients. Follow Nicole on Instagram @jaiwellness or on her website, jaiwellness.com.

source: www.cbc.ca
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You Say Turmeric, I Say Curcumin

Either way, we say healthy

Who doesn’t love the flavours and aromas that turmeric imbues our lives with? But we can also thank this delicious spice for some powerful therapeutic properties. Find out what this yellow jewel can do for you.

If you’ve eaten curry, you’ve likely consumed turmeric. Not only does this spice lend its flavour and yellow colour to delicious curry dishes; it’s also played an important role in ancient medical practices like Ayurveda and traditional Chinese medicine.

Curcumin, found in supplement form at your natural health store, is the active ingredient of the turmeric plant. Over the last few decades, the extract curcumin has been the subject of wide-ranging scientific research for its medicinal properties.

The colour of health may be yellow

Prized for its yellow hue and medicinal properties for, reportedly, 4,000 years, turmeric’s unique qualities are found in its curcuminoid components. Extracted from the turmeric (Curcumin longa L.) plant, curcumin research has uncovered plenty of reason to turn (to) yellow.

Burns and scalds

While you’re in the kitchen cooking up a batch of your favourite curry, you may have occasion to remember that the curcumin in that turmeric you’ve just added to the pan is also useful in a gel to help heal minor burns and scalds.

Research says:

The effectiveness of curcumin gel on the skin is, according to the author of a recent study, related to its powerful anti-inflammatory properties. Research subjects who were treated with a topical curcumin gel after suffering minor burns had less pain and inflammation and improved healing with less than expected scarring—even no scarring in some cases.

Arthritis pain

People who suffer from joint pain and swelling from arthritis, either from osteoarthritis or rheumatoid arthritis, may be able to find some relief with curcumin’s ability to reduce inflammation. And it may help them get around much more easily.

Research says:

Clinical studies have shown a positive effect of curcumin on reducing pain and improving physical function and quality of life for osteoarthritis patients through its anti-inflammatory and cartilage-protective qualities. Preliminary evidence suggests that curcumin may also have the same effect for people with rheumatoid arthritis.

Cancer

In countries where people eat curcumin at levels of about 100 mg to 200 mg a day over long periods of time, there are low rates of certain types of cancer. Curcumin seems to have a powerful effect on cancer cells. In some cases curcumin has shown the ability to step in and reduce the ability of cancer cells to transform, grow, and spread to other parts of the body.

Research says:

The promising results in laboratory studies have inspired researchers all over the world to continue the search for the exact mechanism by which curcumin could help prevent and even offer therapeutic benefits for certain types of cancer. Researchers, in a recent review of years of curcumin studies, suggest that future studies should take a more holistic approach to account for turmeric’s chemically diverse constituents that may synergistically contribute to its potential benefits.

Ulcerative colitis

There is currently no known cure for ulcerative colitis, an inflammatory bowel disease that affects the lining of the large intestine (colon) and rectum. One of the goals of treatment is to prevent relapses of its symptoms and promote remission. This is something that curcumin seems to be able to help with.

Research says:

A Cochrane Database systematic review of studies into curcumin’s effectiveness for maintenance of remission in patients with ulcerative colitis (UC) in 2014 concluded that curcumin may be a safe and effective adjunctive therapy for maintenance of remission in “quiescent” UC.

Alzheimer’s disease?

Elderly villagers in India, where turmeric is a dietary staple, have the lowest rate of Alzheimer’s disease in the world; and researchers have been keen to determine if curcumin may play a role in this. They were intrigued because of curcumin’s antioxidant and anti-inflammatory properties.

Research says:

Though plenty of studies have focused on exploring this possibility, so far there’s no concrete evidence that curcumin is effective in combatting or preventing Alzheimer’s disease. The research continues, though, since laboratory studies have shown some intriguing and promising possibilities.

October 1, 2017 by alive Editorial
source: www.alive.com


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Just 1 Gram of This Spice Boosts Memory in Six Hours

One gram of turmeric at breakfast has been shown by a new study to improve memory in people with memory problems.

In the study itself participants were given 1 gram of turmeric mixed into their ordinary breakfasts (Lee et al., 2014).

Their working memory was tested before and some time after their breakfast, and the results were compared with a placebo-control condition.

Professor Wahlqvist, who led the Taiwanese study, explained the results:

“We found that this modest addition to breakfast improved working memory over six hours in older people with pre-diabetes.”

Diabetes and memory problems are linked because having diabetes makes it more likely that a person will also develop dementia if the diabetes is not well controlled.

Turmeric is a yellow spice already widely used in cooking, especially in Asia.

Turmeric
Memory improved by consuming
small amount of this spice with breakfast.

Its distinctive yellow colour is given to it by a substance called curcumin, which makes up between 3-6% of turmeric.

It is the curcumin which is thought to have an active effect in reducing the memory problems associated with dementia.

Professor Wahlqvist explained the importance of working memory, which was tested in this study:

“Working memory is widely thought to be one of the most important mental faculties, critical for cognitive abilities such as planning, problem solving and reasoning.
Assessment of working memory is simple and convenient, but it is also very useful in the appraisal of cognition and in predicting future impairment and dementia.”

He concluded:

“Our findings with turmeric are consistent with these observations, insofar as they appear to influence cognitive function where there is disordered energy metabolism and insulin resistance.”

source: PsyBlog


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Turmeric Produces ‘Remarkable’ Recovery in Alzheimer’s Patients

Written By: Sayer Ji   Monday, June 10th 2013

Turmeric has been used in India for over 5,000 years, which is likely why still today both rural and urban populations have some of the lowest prevalence rates of Alzheimer’s disease (AD) in the world. A recent study on patients with AD found that less than a gram of turmeric daily, taken for three months, resulted in ‘remarkable improvements.’

Alzheimer’s Disease: A Disturbingly Common Modern Rite of Passage

A diagnosis of Alzheimer’s disease (AD), sadly, has become a rite of passage in so-called developed countries.  AD is considered the most common form of dementia, which is defined as a serious loss of cognitive function in previously unimpaired persons, beyond what is expected from normal aging.

A 2006 study estimated that 26 million people throughout the world suffer from this condition, and that by 2050, the prevalence will quadruple, by which time 1 in 85 persons worldwide will be afflicted with the disease.[1]

Given the global extent of the problem, interest in safe and effective preventive and therapeutic interventions within the conventional medical and alternative professions alike are growing.

Unfortunately, conventional drug-based approaches amount to declaring chemical war upon the problem, a mistake which we have documented elsewhere, and which can result in serious neurological harm, as evidenced by the fact that this drug class carries an alarmingly high risk for seizures, according to World Health Organization post-marketing surveillance statistics.[i][2]

What the general public is therefore growing most responsive to is using time-tested, safe, natural and otherwise more effective therapies that rely on foods, spices and familiar culinary ingredients.

Remarkable Recoveries Reported after Administration of Turmeric

Late last year, a remarkable study was published in the journal Ayu titiled “Effects of turmeric on Alzheimer’s disease with behavioral and psychological symptoms of dementia.” [ii]  Researchers described three patients with Alzheimer’s disease whose behavioral symptoms were “improved remarkably” as a result of consuming 764 milligram of turmeric (curcumin 100 mg/day) for 12 weeks. According to the study:

“All three patients exhibited irritability, agitation, anxiety, and apathy, two patients suffer from urinary incontinence and wonderings. They were prescribed turmeric powder capsules and started recovering from these symptoms without any adverse reaction in the clinical symptom and laboratory data.”

After only 3 months of treatment, both the patients’ symptoms and the burden on their caregivers were significantly decreased.

The report describes the improvements thusly:

“In one case, the Mini-Mental State Examination (MMSE) score was up five points, from 12/30 to 17/30. In the other two cases, no significant change was seen in the MMSE; however, they came to recognize their family within 1 year treatment. All cases have been taking turmeric for more than 1 year, re-exacerbation of BPSD was not seen.”

This study illustrates just how powerful a simple natural intervention using a time-tested culinary herb can be.  Given that turmeric has been used medicinally and as a culinary ingredient for over 5,000 years in Indian culture, even attaining the status of a ‘Golden Goddess,’ we should not be surprised at this result. Indeed, epidemiological studies of Indian populations reveal that they have a remarkably lower prevalence of Alzheimer’s disease relative to Western nations, [3] and this is true for both rural and more “Westernized” urban areas of India.[4]

Could turmeric be a major reason for this?

Turmeric’s Anti-Alzheimer’s Properties.
The GreenMedInfo.com database now contains a broad range of published studies on the value of turmeric, and its primary polyphenol curcumin (which gives it its golden hue), for Alzheimer’s disease prevention and treatment.*

While there are 114 studies on our Turmeric research page indicating turmeric has a neuroprotective set of physiological actions, [5] 30 of these studies are directly connected to turmeric’s anti-Alzheimer’s disease properties.**

Two of these studies are particularly promising, as they reveal that curcumin is capable of enhancing the clearance of the pathological amyloid–beta plaque in Alzheimer’s disease patients,[6] and that in combination with vitamin D3 the neurorestorative process is further enhanced.[7] Additional preclinical research indicates curcumin (and its analogs) has inhibitory and protective effects against Alzheimer’s disease associated β-amyloid proteins.[8] [9] [10]

Other documented Anti-Alzheimer’s mechanisms include:

Anti-inflammatory: Curcumin has been found to play a protective role against β-amyloid protein associated inflammation.[11]
Anti-oxidative: Curcumin may reduce damage via antioxidant properties.[12]

Anti-cytotoxic: Curcumin appears to protect against the cell-damaging effects of β-amyloid proteins.[13] [14]

Anti-amyloidogenic: Turmeric contains a variety of compounds (curcumin, tetrahydrocurcumin, demethoxycurcumin and bisdemethoxycurcumin) which may strike to the root pathological cause of Alzheimer’s disease by preventing β-amyloid protein formation.[15] [16] [17] [18]

Neurorestorative: Curcuminoids appear to rescue long-term potentiation (an indication of functional memory) impaired by amyloid peptide, and may reverse physiological damage by restoring distorted neurites and disrupting existing plaques. [19] [20]

Metal-chelating properties: Curcumin has a higher binding affinity for iron and copper rather than zinc, which may contribute to its protective effect in Alzheimer’s disease, as iron-mediated damage may play a pathological role.[21] [22]

 

Just The Tip of the Medicine Spice Cabinet

The modern kitchen pantry contains a broad range of anti-Alzheimer’s disease items, which plenty of science now confirms. Our Alzheimer’s research page contains research on 97 natural substances of interest. Top on the list, of course, is curcumin. Others include:

Coconut Oil: This remarkable substance contains approximately 66% medium chain triglycerides by weight, and is capable of improving symptoms of cognitive decline in those suffering from dementia by increasing brain-boosing ketone bodies, and perhaps more remarkably, within only one dose, and within only two hours.[23]

Cocoa: A 2009 study found that cocoa procyanidins may protect against lipid peroxidation associated with neuronal cell death in a manner relevant to Alzheimer’s disease.[24]

Sage: A 2003 study found that sage extract has therapeutic value in patients with mild to moderate Alzheimer’s disease.[25]

Folic acid: While most of the positive research on this B vitamin has been performed on the semi-synthetic version, which may have unintended, adverse health effects,  the ideal source for this B vitamin is foliage, i.e. green leafy vegetables, as only foods provide folate. Also, the entire B group of vitamins, especially including the homocysteine-modulating B6 and B12,[26] may have the most value in Alzheimer’s disease prevention and treatment. 

Resveratrol: this compound is mainly found in the Western diet in grapes, wine, peanuts and chocolate. There are 16 articles on our website indicating it has anti-Alzheimer’s properties.[27]

Other potent natural therapies include:

Gingko biloba: is one of the few herbs proven to be at least as effective as the pharmaceutical drug Aricept in treating and improving symptoms of Alzheimer’s disease.[28] [29]

Melissa offinalis: this herb, also known as Lemon Balm, has been found to have therapeutic effect in patients with mild to moderate Alzheimer’s disease.[30]
Saffron: this herb compares favorably to the drug donepezil in the treatment of mild-to-moderate Alzheimer’s disease.[31]

As always, the important thing to remember is that it is our diet and environmental exposures that largely determine our risk of accelerated brain aging and associated dementia. Prevention is an infinitely better strategy, especially considering many of the therapeutic items mentioned above can be used in foods as spices.  Try incorporating small, high-quality culinary doses of spices like turmeric into your dietary pattern, remembering that ‘adding it to taste,’ in a way that is truly enjoyable, may be the ultimate standard for determining what a ‘healthy dose’ is for you.

Notes:

*This statement is not meant to be used to prevent, diagnosis, treat, or cure a disease; rather, it is a statement of fact: the research indexed on our database indicates it


**Our professional database users are empowered to employ the ‘Advanced Database Options’ listed on the top of the Turmeric research page and after clicking the function “Sort Quick Summaries by Title Alphabetically” under  “Available Sorting Options” they can quickly retrieve an alphabetical list of all 613 diseases relevant to the Turmeric research, and then choosing the “Focus” articles selection to the right of the “Alzheimer’s disease” heading to see only the 30 study abstracts relevant to the topic.


Resources

[1] Ron Brookmeyer, Elizabeth Johnson, Kathryn Ziegler-Graham, H Michael Arrighi. Forecasting the global burden of Alzheimer’s disease. Alzheimers Dement. 2007 Jul ;3(3):186-91. PMID: 19595937
[2] Nozomi Hishikawa, Yoriko Takahashi, Yoshinobu Amakusa, Yuhei Tanno, Yoshitake Tuji, Hisayoshi Niwa, Nobuyuki Murakami, U K Krishna. Effects of turmeric on Alzheimer’s disease with behavioral and psychological symptoms of dementia. Ayu. 2012 Oct ;33(4):499-504. PMID: 23723666
[3] V Chandra, R Pandav, H H Dodge, J M Johnston, S H Belle, S T DeKosky, M Ganguli. Incidence of Alzheimer’s disease in a rural community in India: the Indo-US study. Neurology. 2001 Sep 25 ;57(6):985-9. PMID: 11571321
[4] GreenMedInfo.com, Declaring Chemical Warfare Against Alzheimer’s.
[5] GreenMedInfo.com, Turmeric’s Neuroprotective Properties (114 study abstracts)
[6] Laura Zhang, Milan Fiala, John Cashman, James Sayre, Araceli Espinosa, Michelle Mahanian, Justin Zaghi, Vladimir Badmaev, Michael C Graves, George Bernard, Mark Rosenthal. Curcuminoids enhance amyloid-beta uptake by macrophages of Alzheimer’s disease patients. J Alzheimers Dis. 2006 Sep;10(1):1-7. PMID: 16988474
[7] Ava Masoumi, Ben Goldenson, Senait Ghirmai, Hripsime Avagyan, Justin Zaghi, Ken Abel, Xueying Zheng, Araceli Espinosa-Jeffrey, Michelle Mahanian, Phillip T Liu, Martin Hewison, Matthew Mizwickie, John Cashman, Milan Fiala. 1alpha,25-dihydroxyvitamin D3 interacts with curcuminoids to stimulate amyloid-beta clearance by macrophages of Alzheimer’s disease patients. J Alzheimers Dis. 2009 Jul;17(3):703-17. PMID: 19433889
[8] Hongying Liu, Zhong Li, Donghai Qiu, Qiong Gu, Qingfeng Lei, Li Mao. The inhibitory effects of different curcuminoids onβ-amyloid protein, β-amyloid precursor protein and β-site amyloid precursor protein cleaving enzyme 1 in swAPP HEK293 cells. Int Dent J. 1996 Feb;46(1):22-34. PMID: 20727383
[9] Shilpa Mishra, Mamata Mishra, Pankaj Seth, Shiv Kumar Sharma. Tetrahydrocurcumin confers protection against amyloidβ-induced toxicity. Neuroreport. 2010 Nov 24. Epub 2010 Nov 24. PMID: 21116204
[10] Xiao-Yan Qin, Yong Cheng, Long-Chuan Yu. Potential protection of curcumin against intracellular amyloid beta-induced toxicity in cultured rat prefrontal cortical neurons. Neurosci Lett. 2010 Aug 9;480(1):21-4. PMID: 20638958
[11] Hong-Mei Wang, Yan-Xin Zhao, Shi Zhang, Gui-Dong Liu, Wen-Yan Kang, Hui-Dong Tang, Jian-Qing Ding, Sheng-Di Chen. PPARgamma agonist curcumin reduces the amyloid-beta-stimulated inflammatory responses in primary astrocytes. J Alzheimers Dis. 2010;20(4):1189-99. PMID: 20413894
[12] G P Lim, T Chu, F Yang, W Beech, S A Frautschy, G M Cole. The curry spice curcumin reduces oxidative damage and amyloid pathology in an Alzheimer transgenic mouse. J Neurosci. 2001 Nov 1;21(21):8370-7. PMID: 11606625
[13] Xiao-Yan Qin, Yong Cheng, Long-Chuan Yu. Potential protection of curcumin against intracellular amyloid beta-induced toxicity in cultured rat prefrontal cortical neurons. Neurosci Lett. 2010 Aug 9;480(1):21-4. PMID: 20638958
[14] D S Kim, S Y Park, J K Kim. Curcuminoids from Curcuma longa L. (Zingiberaceae) that protect PC12 rat pheochromocytoma and normal human umbilical vein endothelial cells from betaA(1-42) insult. Neurosci Lett. 2001 Apr 27;303(1):57-61. PMID: 11297823
[15] R Douglas Shytle, Paula C Bickford, Kavon Rezai-zadeh, L Hou, Jin Zeng, Jun Tan, Paul R Sanberg, Cyndy D Sanberg, Bill Roschek, Ryan C Fink, Randall S Alberte. Optimized turmeric extracts have potent anti-amyloidogenic effects. Curr Alzheimer Res. 2009 Dec;6(6):564-71. PMID: 19715544
[16] Fusheng Yang, Giselle P Lim, Aynun N Begum, Oliver J Ubeda, Mychica R Simmons, Surendra S Ambegaokar, Pingping P Chen, Rakez Kayed, Charles G Glabe, Sally A Frautschy, Gregory M Cole. Curcumin inhibits formation of amyloid beta oligomers and fibrils, binds plaques, and reduces amyloid in vivo. Neurochem Int. 2009 Mar-Apr;54(3-4):199-204. Epub 2008 Nov 30. PMID: 15590663
[17] Can Zhang, Andrew Browne, Daniel Child, Rudolph E Tanzi. Curcumin decreases amyloid-beta peptide levels by attenuating the maturation of amyloid-beta precursor protein. Gastroenterology. 2006 Jan;130(1):120-6. PMID: 20622013
[18] Ranjit K Giri, Vikram Rajagopal, Vijay K Kalra. Curcumin, the active constituent of turmeric, inhibits amyloid peptide-induced cytochemokine gene expression and CCR5-mediated chemotaxis of THP-1 monocytes by modulating early growth response-1 transcription factor. J Neurochem. 2004 Dec;91(5):1199-210. PMID: 15569263
[19] Touqeer Ahmed, Anwarul-Hassan Gilani, Narges Hosseinmardi, Saeed Semnanian, Syed Ather Enam, Yaghoub Fathollahi. Curcuminoids rescue long-term potentiation impaired by amyloid peptide in rat hippocampal slices. Synapse. 2010 Oct 20. Epub 2010 Oct 20. PMID: 20963814
[20] M Garcia-Alloza, L A Borrelli, A Rozkalne, B T Hyman, B J Bacskai. Curcumin labels amyloid pathology in vivo, disrupts existing plaques, and partially restores distorted neurites in an Alzheimer mouse model. J Neurochem. 2007 Aug;102(4):1095-104. Epub 2007 Apr 30. PMID: 17472706
[21] Larry Baum, Alex Ng. Curcumin interaction with copper and iron suggests one possible mechanism of action in Alzheimer’s disease animal models. J Alzheimers Dis. 2004 Aug;6(4):367-77; discussion 443-9. PMID: 15345806
[22] Silvia Mandel, Tamar Amit, Orit Bar-Am, Moussa B H Youdim. Iron dysregulation in Alzheimer’s disease: multimodal brain permeable iron chelating drugs, possessing neuroprotective-neurorescue and amyloid precursor protein-processing regulatory activities as therapeutic agents. Prog Neurobiol. 2007 Aug;82(6):348-60. Epub 2007 Jun 19. PMID: 17659826
[23] Mark A Reger, Samuel T Henderson, Cathy Hale, Brenna Cholerton, Laura D Baker, G S Watson, Karen Hyde, Darla Chapman, Suzanne Craft. Effects of beta-hydroxybutyrate on cognition in memory-impaired adults. Neurobiol Aging. 2004 Mar;25(3):311-4. PMID: 15123336
[24] Eun Sun Cho, Young Jin Jang, Nam Joo Kang, Mun Kyung Hwang, Yong Taek Kim, Ki Won Lee, Hyong Joo Lee. Cocoa procyanidins attenuate 4-hydroxynonenal-induced apoptosis of PC12 cells by directly inhibiting mitogen-activated protein kinase kinase 4 activity. Free Radic Biol Med. 2009 May 15;46(10):1319-27. Epub 2009 Feb 25. PMID: 19248828
[25] S Akhondzadeh, M Noroozian, M Mohammadi, S Ohadinia, A H Jamshidi, M Khani. Salvia officinalis extract in the treatment of patients with mild to moderate Alzheimer’s disease: a double blind, randomized and placebo-controlled trial. J Clin Pharm Ther. 2003 Feb;28(1):53-9. PMID: 12605619
[26] Celeste A de Jager, Abderrahim Oulhaj, Robin Jacoby, Helga Refsum, A David Smith. Cognitive and clinical outcomes of homocysteine-lowering B-vitamin treatment in mild cognitive impairment: a randomized controlled trial. Int J Geriatr Psychiatry. 2011 Jul 21. Epub 2011 Jul 21. PMID: 21780182
[27] GreenMedInfo.com, Resveratrol’s Anti-Alzheimer’s properties
[28] S Yancheva, R Ihl, G Nikolova, P Panayotov, S Schlaefke, R Hoerr,. Ginkgo biloba extract EGb 761(R), donepezil or both combined in the treatment of Alzheimer’s disease with neuropsychiatric features: a randomised, double-blind, exploratory trial. Aging Ment Health. 2009 Mar;13(2):183-90. PMID: 19347685
[29] M Mazza, A Capuano, P Bria, S Mazza. Ginkgo biloba and donepezil: a comparison in the treatment of Alzheimer’s dementia in a randomized placebo-controlled double-blind study. Eur J Neurol. 2006 Sep;13(9):981-5. PMID: 16930364
[30] S Akhondzadeh, M Noroozian, M Mohammadi, S Ohadinia, A H Jamshidi, M Khani. Melissa officinalis extract in the treatment of patients with mild to moderate Alzheimer’s disease: a double blind, randomised, placebo controlled trial. J Neurol Neurosurg Psychiatry. 2003 Jul;74(7):863-6. PMID: 12810768
[31] Shahin Akhondzadeh, Mehdi Shafiee Sabet, Mohammad Hossein Harirchian, Mansoreh Togha, Hamed Cheraghmakani, Soodeh Razeghi, Seyyed Shamssedin Hejazi, Mohammad Hossein Yousefi, Roozbeh Alimardani, Amirhossein Jamshidi, Shams-Ali Rezazadeh, Aboulghasem Yousefi, Farhad Zare, Atbin Moradi, Ardalan Vossoughi. A 22-week, multicenter, randomized, double-blind controlled trial of Crocus sativus in the treatment of mild-to-moderate Alzheimer’s disease. Psychopharmacology (Berl). 2010 Jan;207(4):637-43. Epub 2009 Oct 20. PMID: 19838862


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Spices and Herbs With a Huge Impact

Medicinal herbs and spices have been used with great effectiveness from ancient times.

Find out how these seven spices & herbs can make a huge impact on your daily health.

Cloves – Found to have the highes
t antioxidant content of all spices an be used as a painkiller and has been used for centuries to treat tooth aches and gum pain. Eases cold and allergies, and oil of clo
ves is useful as antiseptic in mouthwash.

Oregano – 1/2 tsp has the same amount of antioxidants as a quarter cup of almonds and four times the antioxidant activity of blueberries…Go greek make a greek salad and sprinkle on the oregano Oregano is rich in Vitamin K, iron, maganese, and kills e.coli, salmonella, and virtually all food-borne pathogens.

Ginger – Over 50 antioxidants have been found in ginger. It helps increase circulation, calms digestive problems. Ginger has also been used to treat food poisoning, shown to lower cholesterol, treat arthritis, reduce inflammation, and can be used to help increase insulin sensivity in diabetics.


Cinnamon – Plays an important role in regulating blood sugar in people with diabetes. Clinical studies have shown a consistent intake of cinnamon daily help reduce glucose, triglyceride, and LDL cholestrol with type II diabetics.

Tumeric – The bright neon yellow color comes from the phytochemical Curcumin and can eliminate cancer cells, help reduce obesity, and metabolic diseases. Scientists have found by creating a new molecule from curcumin, called CNB-001, this molecule triggers the mechanisms that safeguard and restore brain cells after a stroke.

Rosemary – Blocks HCAs or carcinogenic compounds found your favorite grilled meats. Rosemary oil can improve cognitive performance and fight off free radical’s that cause Alzheimer’s, stroke, and dementia.

Mustard – The compound AITC compound found in mustard seed is known to be an anti-cancer compound – this plant compound is also found in wasabi & horseradish. Studies show that AITC, stopped the growth of bladder cancer by 33%.

source: www.foodlve.com


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How Turmeric Reduces Oxidative Stress and Supports Your Brain and Heart

June 13, 2013  By Dylan Charles   Mae Chan, Prevent Disease   Waking Times

Curcumin has increasingly come under the scientific spotlight in recent years, with studies investigating its potential health benefits. It has even been found to outperform pharmaceuticals in preventing disease. Curcumin is a compound found in the spice turmeric which gives it a natural pigment. It has been linked to a range of health benefits, including potential protection against prostate cancer, Alzheimer’s, protection against heart failure, diabetes, and arthritis. Two studies add to that mix with benefits for arterial aging and cognition.

The first of the news studies, published in Experimental Gerontology and performed by scientists from the University of Colorado, found that curcumin was associated with improved vascular health in aging lab mice.

Curcumin is a diferuloylmethane derived from turmeric (popularly called “curry powder”) that has been shown to interfere with multiple cell signaling pathways, including cell cycle, proliferation, survival, invasion, metastasis and inflammation.

Adding curcumin to human cells with the blood cancer multiple myeloma, Dr. Bharat B. Aggarwal of the University of Texas MD Anderson Cancer Center in Houston and his colleagues found, stopped the cells from replicating. And the cells that were left died.

Researchers at Rutgers, the State University of New Jersey, found that a combination of turmeric and phenethyl isothiocyanate (PEITC) was effective against prostate cancer. PEITC is abundant in a group of vegetables that includes cauliflower, cabbage, watercress, winter cress, broccoli, Brussels sprouts, kale, kohlrabi and turnips.

Intake of curcumin at ‘physiologically attainable’ doses have recently been reported to slow the development of prostate cancers by jamming receptors linked to cancer tumour growth, say researchers.

Supplementing the chow of aged mice with 0.2% curcumin “ameliorates age-associated large elastic artery stiffening, NO-mediated vascular endothelial dysfunction, oxidative stress and increases in collagen […] in mice”, wrote the researchers, led by Bradley Fleenor.

Study Details

Fleenor and his co-workers gave old mice the equivalent of 14 grams per day of curcumin when compared with a 60 kg person.

“Because of curcumin’s poor absorption and rapid metabolism, clinical trials in humans also have used high doses of curcumin (8 to 12 g) similar to the amount our old mice consumed, while observing only infrequent, minor side effects,” they explained.

“Our results provide the first evidence that dietary curcumin supplementation ameliorates two clinically important markers of arterial dysfunction with aging: large elastic artery stiffening and endothelial dysfunction.

“Given its accessibility and safety, these pre-clinical findings provide the experimental basis for future translational studies assessing the potential for curcumin to treat arterial dysfunction with aging and reduce CVD risk in humans,” they concluded.

Healthy Brain Aging

The second curcumin study, published in Biogerontology and performed by researchers from Selcuk University in Turkey, examined the effects of curcumin on cognitive functions in old female rats.

Lab animals were given either curcumin or corn oil (control) for seven days, and a further five days when they were tested using the Morris water maze.

Results showed that curcumin supplementation decreased the time needed by the animals to reach the platform, and also decreased the total distance traveled by the rats.

“In addition to the behavioral testing, biochemical results showed that MDA levels decreased in brain tissue by curcumin supplementation,” they said. MDA (malondialdehyde) is a marker of oxidative stress.

“It may be concluded that, curcumin supplementation improves cognitive functions by decreasing the lipid peroxidation in brain tissue of aged female rats.”

One of the most comprehensive summaries of a review of 700 turmeric studies to date was published by the respected ethnobotanist James A. Duke, Phd. He showed that turmeric appears to outperform many pharmaceuticals in its effects against several chronic, debilitating diseases, and does so with virtually no adverse side effects.

Alzheimer’s 

Duke found more than 50 studies on turmeric’s effects in addressing Alzheimer’s disease. The reports indicate that extracts of turmeric contain a number of natural agents that block the formation of beta-amyloid, the substance responsible for the plaques that slowly obstruct cerebral function in Alzheimer’s disease.

Arthritis 

Turmeric contains more than two dozen anti-inflammatory compounds, including sixdifferent COX-2-inhibitors (the COX-2 enzyme promotes pain, swelling and inflammation; inhibitors selectively block that enzyme). By itself, writes Duke, curcumin – the component in turmeric most often cited for its healthful effects – is a multifaceted anti-inflammatory agent, and studies of the efficacy of curcumin have demonstrated positive changes in arthritic symptoms.

Cancer

Duke found more than 200 citations for turmeric and cancer and more than 700 for curcumin and cancer. He noted that in the handbookPhytochemicals: Mechanisms of Action, curcumin and/or turmeric were effective in animal models in prevention and/or treatment of colon cancer, mammary cancer, prostate cancer, murine hepato-carcinogenesis (liver cancer in rats), esophageal cancer, and oral cancer. Duke said that the effectiveness of the herb against these cancers compared favorably with that reported for pharmaceuticals. 

Weight Loss

Dietary curcumin can stall the spread of fat-tissue by inhibiting new blood vessel growth, called angiogenesis, which is necessary to build fat tissue. Curcumin-treated groups have been found to have less blood vessel growth in fat tissue. Blood glucose, triglyceride, fatty acid, cholesterol and liver fat levels also were lower.

Parkinson’s

A team of researchers has now demonstratedthat slow-wriggling alpha-synuclein proteins are the cause of clumping, or aggregation, which is the first step of diseases such as Parkinson’s. A new study led by Ahmad, which appears in the Journal of Biological Chemistry, shows that curcumin can help prevent clumping.

– Only 1 percent of the elderly in India develop Alzheimer’s disease – this is one-quarter the rate of Alzheimer’s development in North America. This difference is thought to be due in part to regular consumption of curry in India.
– Daily intake of curcumin may decrease the risk of developing polyps in the colon, which in turn, decreases the risk of developing colorectal cancer.
– Regular consumption of turmeric may help to ease pain and inflammation that accompanies arthritis.
– Curcumin may be helpful in the treatment of some cases of cystic fibrosis.
– Curcumin can help to effectively treat skin cancer cells.
– Turmeric may help to prevent the spread of breast cancer cells.

About the Author
Mae Chan holds degrees in both physiology and nutritional sciences. She is also blogger and and technology enthusiast with a passion for disseminating information about health.


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The 3 Keys to a Healthy Brain

Maria Rodale  July 6, 2013

We all have those moments–a forgotten appointment, a name we can’t recall, a word that’s on the tip of our tongue. For the most part, these incidents don’t worry us. However, as we age, they seem to increase in significance. We wonder if we’re losing our edge. With Alzheimer’s disease and dementia constantly in the news, we can find ourselves falling prey to a climate of fear that plays on our worst anxieties about losing our cognitive capacities.

Luckily, there are a number of steps we can take to preserve our mental sharpness. Like any other organ, the brain responds to input. Not just mental and emotional input, but diet and exercise, as well. Many of the strategies we adopt to maintain overall health also support the brain. We can keep that mental acuity, and it only takes a few simple brain-friendly habits.

1: Brain-Friendly Food and Supplements

One of the brain’s biggest enemies is oxidative stress from excess free radicals, which are generated by toxins, exercise, illness, stress, and normal metabolic processes, among other factors. Like a lunchroom bully, free radicals (atoms or molecules that are short one electron) take what they need from other atoms. As levels of free radicals increase, one theft leads to another, creating a cascade of inflammatory chain reactions that can damage cells down to their DNA.

Antioxidants can help block this cycle, which is why we hear so much about these super nutrients, and there is a wide variety of sources–foods, herbs, and supplements–to choose from. Blueberries are a rich source and have been shown to protect neurons from oxidative stress. Other good antioxidant food choices are beans, cranberries, artichokes, prunes, and raspberries. Herbs and spices like sage, rosemary, ginger, and turmeric are chock-ull of antioxidant compounds to protect the brain and support numerous other areas of health, as well.

Stock up on foods that are rich in omega-3 fatty acids, such as fish, flaxseed, raw nuts and seeds, and grass-fed beef. While omega-3s are more often touted for their heart-health benefits, they are crucial to brain health, too. A study published in the journal Neurology found that people deficient in omega-3s had smaller brains and did more poorly in cognitive tests. The researchers asserted that omega-3s reduce signs of aging in the brain.


Vitamin E has also been associated with improved cognitive health. In addition, one study indicated it can help patients recover after a stroke. Vitamin E is also a potent antioxidant. Be sure to look for the natural form called d-alpha tocopherol, often found with a blend of mixed tocopherols. Avoid dl-alpha tocopherol, a form that is synthetic and not well absorbed.

As noted, oxidation can play a big role in damaging neurons, leading to cognitive decline. One of the most potent antioxidant supplements is a botanical called honokiol. Derived from magnolia bark, honokiol is 1,000 times more powerful as an antioxidant than vitamin E and has been shown protect the brain in numerous ways. Because its molecules are so small, honokiol taken orally is very easily absorbed, and even has the unique ability to pass through the blood/brain barrier. This allows honokiol to exert it effects directly on brain tissue. Honokiol is shown to improve mood, influencing GABA and other neurotransmitters that help mediate both anxiety and depression. It also is shown to aid in stroke damage and protect against the amyloid plaque associated with Alzheimer’s disease.

Another supplement that benefits brain health is curcumin, the active ingredient in turmeric. In a recent study from the Salk Institute, a drug derived from curcumin reversed Alzheimer’s disease in mice. This is not an isolated study. Other research has shown that curcumin influences neuron creation and enhances memory.

2: Exercise

Multiple studies have shown a close relationship between exercise and improved brain function. One project found that women over 65 who walked 30 minutes a day slowed their cognitive decline. When measuring mental acuity, the researchers found that the people who exercised appeared several years younger than those in the control group, who did not exercise at all.

Another study comparing activity levels and brain health looked at people over age 70. The more active group was significantly less likely to develop cognitive problems. The study also helped clarify the types of activities that promote cognitive health. In addition to “normal” exercise, the researchers found that simple actions, such as standing up and walking around the room, were also beneficial.

Other research has shown that exercise can actually increase brain size. One study used MRIs to compare brain sizes in people who exercised with those who did not. The group of exercisers did significantly better. Maintaining a larger brain is important because one of the side effects of aging is reduced brain volume, which may be implicated in cognitive decline.

3: Meditation

The calming effects of meditation are well documented. However, some research has shown that the practice actually changes brain architecture. Scientists at UCLA found that meditation increases the folding in the cerebral cortex, a process called cortical gyrification, which improves the brain’s ability to process information. Specifically, increased gyrification helps us retrieve memories, form decisions, and focus.

To me, the most striking aspect of these recommendations is their applicability to overall health. Diet, appropriate supplements, exercise, and meditation also benefit heart health, and they can reduce the risk of cancer, diabetes, and metabolic syndrome–plus, they simply make us feel better. In the big picture, good practices support health at all levels, forming a foundation for mind-body wellness, longevity, and vitality.

source: Care2.com