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Using Food To Ward Off Anxiety

It’s normal to feel anxious or worried from time to time. Work deadlines, writing an exam or giving a presentation, for example, can trigger short-lived anxiety.

People with an anxiety disorder, however, experience persistent and intense anxiety, worry or fear that’s out of proportion to everyday occurrences. Symptoms interfere with daily life, impacting thoughts, emotions, behaviour and physical health. Anxiety disorders include panic disorder, phobias, social anxiety disorder and generalized anxiety disorder (excessive worry about ordinary, everyday situations). Anxiety often goes hand in hand with depression.

Growing scientific evidence suggests that the foods we eat – and the ones that we don’t – play a role in developing and treating anxiety.

The diet-anxiety connection

Components in whole foods can influence mood in a number of ways. Some nutrients are used to synthesize brain chemicals (neurotransmitters) that regulate emotions, while others impact how the brain responds to stress.

An imbalance of omega-3 fats, which are essential for the integrity of brain cell membranes, may alter how brain cells communicate with one another. Certain nutrients may also dampen inflammation in the brain.

While diet can’t cure anxiety – nor can it take the place of medication – research suggests that the following strategies may help reduce symptoms.

Follow a healthy dietary pattern. Studies conducted in many different countries have found that healthy traditional diet patterns, including the Mediterranean diet and vegetarian diets, are associated with a lower risk of anxiety disorders.

In general, eating a diet that’s low in added sugars and emphasizes vegetables, fruits, whole grains, lean proteins, nuts and beans and lentils guards against anxiety. In contrast, a “Western-style” diet consisting of refined grains, highly processed foods and sugary foods increases the risk.

Include omega-3′s, fatty fish. Observational studies have linked a higher intake of oily fish and DHA (docosahexaenoic acid), an omega-3 fatty acid found in fish, to a lower risk of anxiety disorders in children, adults and pregnant women.

A randomized controlled trial published in 2013 found that medical students who received omega-3 supplements (2.5 grams a day) experienced a 20-per-cent reduction in anxiety compared with the placebo group. They also had lower blood levels of stress-induced inflammatory proteins.

Salmon, trout, sardines, herring, mackerel and anchovies are good sources of omega-3 fatty acids; these fish are also low in mercury. Include them in your diet at least twice a week. DHA supplements made from algae are available for people who eat a vegetarian diet.

Try fermented foods. Preliminary evidence suggests that a regular intake of fermented foods, a source of probiotic bacteria, may reduce the risk of social anxiety in women. Fermented foods include kefir, kombucha, kimchi, unpasteurized sauerkraut and yogurt.

Probiotics may also help ease anxiety symptoms. A review of 10 randomized controlled trials, published in 2017, concluded that probiotic supplements significantly improved anxiety. However, the strain of probiotic, the dose and the duration of treatment varied widely across studies.

Once consumed, probiotic bacteria take up residence in the gut, where they help to maintain a strong intestinal barrier. When the lining of the gut becomes more permeable than normal, toxins can escape into the bloodstream, triggering an inflammatory response that may interfere with neurotransmitters.

It’s also thought that probiotics in the gut increase the production of serotonin, a neurotransmitter that regulates stress and emotions.

Increase magnesium, zinc. Findings from a number of studies have shown that a deficiency of these two minerals, needed for healthy brain cells, can lead to anxiety.

Excellent sources of magnesium include oat bran, brown rice, quinoa, spinach, Swiss chard, hemp seeds, pumpkin seeds, almonds, cashews, black beans, lentils, tofu and edamame.

You’ll find zinc in oysters, beef, crab, pork, chicken, pumpkin seeds, cashews, chickpeas, yogurt, milk and fortified breakfast cereals.

Avoid triggers. Eat at regular intervals during the day to prevent low blood sugar, which could precipitate feelings of anxiety. Limit or avoid caffeine and alcohol, which can also make you feel jittery and nervous.

Drink water throughout the day to prevent becoming dehydrated; even mild dehydration can worsen your mood.

LESLIE BECK         THE GLOBE AND MAIL         August 23, 2020

Leslie Beck, a Toronto-based private practice dietitian, is Director of Food and Nutrition at Medcan.

source: www.theglobeandmail.com

salmon

 

9 Foods That Calm Anxiety
(and 3 That Make It Worse)

Scientists are just beginning to recognize the connection between food and our brain. Eat these nutrients for a wave of calming feelings that keep worry away.

Omega-3 fatty acids make your brain happy

Doctors often know how to calm anxiety, or treat it, with therapy and medications, but the answer to calming the condition could be hiding in plain sight: the foods we eat. Doctors and nutritionists are starting to understand more about how certain nutrients, or lack of them, affect the brain. “Our brain has very high energy and nutrient requirements,” says clinical nutritionist and health coach Melissa Reagan Brunetti, CNC. “Nutritional deficiencies and dietary patterns can affect its function, and alter brain chemistry and the formulation of neurotransmitters—chemicals in the brain that can stimulate and calm.” These neurotransmitters influence our mood as well as our appetite, she says. A study from Ohio State University showed one nutrient that’s especially good for reducing anxious symptoms is omega 3 fatty acids, found in fatty fish like wild salmon, flaxseed, walnuts, and chia seeds. “Our brains need fat from dietary sources to function properly,” Brunetti says. “If you are not eating a sufficient amount of beneficial fats, your brain will suffer.”

Probiotics are good for the gut

Surprisingly, another calming food source is probiotics. “Your gut bacteria is needed for production of neurotransmitters, including serotonin, dopamine, and GABA [gamma-aminobutyric acid], which all play a role in mood,” Brunetti says. “The microbiome [gut bacteria] has a direct link to the brain and the immune system, so restoring balance in the gut of good and bad bacteria through use of probiotics can benefit the brain.” Recent research has found that probiotics may actually work to treat, or even prevent, anxious feelings. You can either take a probiotic supplement or eat foods that have been fermented, a process which encourages good bacteria to grow, and has been shown in studies as a way how to calm anxiety. “I like to see patients eat more fermented foods like yogurt, sauerkraut, and kefir, as the kinds of bacteria in your gut influence anxiety,” says Drew Ramsey, MD, a psychiatrist who specializes in using dietary changes to help balance moods, and author of Eat Complete. Another fermented food you probably already have in your fridge? Pickles!

Caffeine makes you anxious

Although some of us feel like we’re miserable until we’ve had our morning cup of java, coffee and other caffeinated foods and drinks actually worsen anxious feelings. Because it’s a stimulant for the nervous system, it increases heart rate, blood pressure, and body temperature. According to the University of Michigan, coffee can lead to symptoms of worrying like nervousness, sweating, and shaking. A study from Brazil found that caffeine actually induced panic attacks in people with an anxious disorder. Another study, from Wake Forest University, found that caffeine reduced blood flow to the brain by 27 percent. Not to mention that it can mess with sleep, which is essential for brain health. “Limiting caffeine intake can help quell inflammation and contribute to improved brain function,” Brunetti says. Likewise, Dr. Ramsey suggests avoiding energy drinks with caffeine, as well as indulging in too much dark chocolate (stick to one or two squares a day).

Water keeps everything flowing smoothly

How to calm anxiety in one step? Drink good old fashioned water. “Staying hydrated with clean water is very important,” Brunetti says. A study from the University of Connecticut showed that even mild dehydration can cause mood problems. According to the study’s author, Lawrence E. Armstrong, PhD, by the time you feel thirsty it’s too late. “Our thirst sensation doesn’t really appear until we are one or two percent dehydrated,” he says. “By then dehydration is already setting in and starting to impact how our mind and body perform.” The connection behind dehydration and anxious symptoms is not totally known; but the UConn study authors think it may be part of an ancient warning system alerting us to find water for survival. So, you should be sure to consume water throughout the day.

Stay away from refined sugar and processed foods

Sweets and processed foods all are, not surprisingly, bad for your mental health. Sugar and refined carbs cause a spike in blood sugar followed by a sudden drop. A study from Columbia University found that the more refined carbs and sugar women ate, the higher their risk for mood changes and depression. Another study, from the United Kingdom, found that eating processed meat and fried foods had similar responses, possibly because of the link with heart disease and inflammation, which are also associated with mental health problems. “Skip highly processed foods, as these are mainly simple sugars and vegetable oils,” Dr. Ramsey suggests. Instead, try eating more complex carbs like whole grains, which were linked to fewer mental health issues in the Columbia study.

Alcohol brings you down

Alcohol is a depressant but it can also worsen anxiety symptoms. And unfortunately, the two often go hand-in-hand—in a study that took place over 14 years, researchers found that people with social anxiety disorder (SAD) were 4.5 times more likely to develop alcohol dependence. The Anxiety and Depression Association of America says that 20 percent of people with SAD also suffer from alcohol abuse or dependence. Drinking can seem like a good way to calm your nerves, but in reality, it causes spikes and dips in blood sugar, dehydrates you, and causes impaired brain function—all of which can lead to anxious feelings, which then make you want to drink more, creating a vicious cycle. According to the National Institute on Alcohol Abuse and Alcoholism, drinking a lot can cause changes in the brain’s neurotransmitters that may induce these symptoms. For this reason, Brunetti says it’s best to reduce or eliminate alcohol.

Load up on antioxidants

Here’s another reason antioxidants are superfoods: They can help quell anxious moods. “Antioxidants protect the brain against oxidative stress [free radicals],” Brunetti says. “Oxidative stress leads to inflammation, which can impair neurotransmitter production.” Research by the State University of New York found that anxious symptoms are linked with a lower antioxidant state, and that antioxidants could actually help treat mood issues as well. So which nutrients are antioxidants, and which foods contain them? “Diets rich in beta-carotene like carrots, sweet potatoes, squash, spinach, and kale; vitamin C like citrus fruits, red peppers, Brussels sprouts, broccoli, and strawberries; and vitamin E like almonds, avocado, spinach, sunflower seeds, spinach, and sweet potatoes, are essential for supporting optimal brain function,” Brunetti says. Another powerful antioxidant Brunetti says is shown to combat anxious feelings is the trace mineral selenium, found in Brazil nuts, halibut, grass-fed beef, turkey, chicken, and eggs. Also, studies have shown that upping your zinc, which has antioxidant properties, leads to fewer anxious feelings. Cashews are a great source of zinc.

Magnesium is calming

Another nutrient that might stave off anxious symptoms is magnesium. “Magnesium is a calming mineral that has been found to induce relaxation,” Brunetti says. In an Austrian study with mice, diets low in magnesium increased anxious behaviors. Research has shown that magnesium may also help treat mental health issues in humans. According to the University of Maryland Medical Center, inadequate magnesium reduces levels of the neurotransmitter serotonin, and antidepressants have been shown to increase magnesium in the brain—evidence of a positive link. “Magnesium can act at the blood brain barrier to prevent the entrance of stress hormones into the brain,” psychiatrist Emily Deans, MD, writes on Psychology Today. “All these reasons are why I call magnesium ‘the original chill pill.’” Dr. Ramsey suggests eating eggs and greens, like spinach and Swiss chard, for magnesium. Other sources include legumes, nuts, seeds, and avocado.

Try tryptophan

We usually think of tryptophan as the nutrient in turkey that puts us to sleep after Thanksgiving—and in fact, tryptophan is an amino acid that the body needs to produce the neurotransmitter serotonin, which helps regulate sleep and moods. According to the University of Michigan, tryptophan may help reduce anxious feelings. In one small study, participants who ate a food bar rich in tryptophan reported fewer symptoms than those who ate a bar without tryptophan. More research is needed, but it seems likely that there is a connection. Tryptophan is in most protein-rich foods like turkey and other meats, nuts, seeds, beans, and eggs. (Incidentally, protein is also important for the production on the neurotransmitter dopamine, which can benefit mood as well.)

B vitamins bump up good feelings

Harvard Medical School advises eating foods rich in B vitamins, like beef, avocado, and almonds, to help ward off anxious feelings. “B vitamins have positive effects on the nervous system, and deficiencies have been linked to anxious disorders,” Brunetti says. According to the University of Maryland Medical Center, vitamin B6 helps the body make several neurotransmitters, including serotonin, which influence mood. A study from Australia found that stressed-out workers who were given a high dose of B vitamins felt less strained and in a better mood after 12 weeks. Another study, from the University of Miami, found that depressed adults who took a vitamin B complex had fewer depressive and anxious symptoms after two months. “Another nutrient that seems to matter is choline, found in eggs, which is a cousin of B vitamins,” Dr. Ramsey says. More research is needed, but these results are promising.

Cozy up with herbal teas

So you might not want to indulge in too much coffee, but you can relax with a mug of herbal tea in order to feel less anxious. “Great options for herbal teas are chamomile, skullcap, and kava kava to start,” Dr. Ramsey says. A study from the University of Pennsylvania found that participants who took chamomile for eight weeks experienced fewer anxious symptoms than those that didn’t. However, be aware that kava can interact with anti-anxiety and antidepressant meds, so talk to your doctor first if you’re on them. Plus, it’s so relaxing that high doses of it could impair your ability to drive, according to one study. If you’re using herbs for anxiety, steer clear of ones that are stimulating, such as ginseng, cautions Dr. Ramsey, because they might actually make anxious feelings worse.

It’s not just what you eat, but how

How to calm anxiety? Pay attention to how and when you eat. Bad habits can have a negative effect on anxious moods, which “get worse when people have low blood sugar,” Dr. Ramsey says. “A simple step people often forget is to eat regularly.” Brunetti says if low blood sugar is an issue for you (in other words, if you get “hangry”), eating smaller, frequent meals throughout the day can help. According to Harvard Medical School, there is evidence that our Western diet, with its focus on refined carbs and processed foods, might not be great for anxious moods; instead, Mediterranean or Japanese diets, which include a lot of veggies and fish, may be the way to go. But, be careful of fad diets that eliminate entire food groups. “Diets that are too low in [complex] carbohydrates can also be detrimental” for anxious feelings, Brunetti says. “Include a variety of foods in your diet to ensure you are getting a wide range of nutrients needed to calm the mind.”

Tina Donvito      November 21, 2018

source: www.rd.com


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Weight Loss: The Best Meal Timings To Slim Down

The meal timings that increase weight loss, lower blood sugar and fight diabetes.

Starting the day with an energy-boosting breakfast, having a medium-sized lunch and ending with a humble dinner might be the answer to weight loss, research finds.

The study shows that a high-energy breakfast, when added to the meal schedules of obese and type 2 diabetes patients, improves blood glucose levels, and boosts weight loss.

The results revealed that people who ate a high-energy breakfast lost 5 kg (11 pounds) but those in a comparison group put on 1.4 kg (3.1 pounds).

Professor Daniela Jakubowicz, the study’s first author, said:

“The hour of the day — when you eat and how frequently you eat — is more important than what you eat and how many calories you eat.
Our body metabolism changes throughout the day.
A slice of bread consumed at breakfast leads to a lower glucose response and is less fattening than an identical slice of bread consumed in the evening.”

Professor Jakubowicz and colleagues recruited a group of obese and diabetic patients who were on insulin therapy.

The participants were divided randomly into two groups to take the same number of daily calories but with two different diets.

The meal schedule for the first group was a large breakfast, an average lunch, and a light dinner for three months.

The total amount of daily calories was 1,600, in which breakfast made up 50 percent of this number, lunch 33 percent, and dinner 17 percent.

The other group had six meals designed for diabetes and weight loss, consisting of six meals which were distributed evenly during the day.

This group also consumed 1,600 kcal a day, but breakfast made up 20 percent of the proportion, lunch 25 percent, dinner 25 percent — plus they had three snacks, which each counted for 10 percent of total daily calories.

The study compared the impact of each diet plan on appetite, insulin level, weight loss, and concentration of glucose in the blood (overall glycemia) of participants.

After three months, the high-energy breakfast group lost 5 kg (11 pounds) but those who were in the the six-meal group put on 1.4 kg (3.1 pounds) more weight.

Overall, glucose levels in the first high-energy breakfast group decreased by 38 mg/dl but this was 17 mg/dl for the six-meal group.

The insulin dosage in the high-energy breakfast group reduced by 20.5 units per day, but the other group required 2.2 units per day more insulin.

Moreover, the hunger and cravings for carbs reduced a lot in the high-energy breakfast group, while it was the opposite for the other group.

Professor Jakubowicz, said:

“This study shows that, in obese insulin-treated type 2 diabetes patients, a diet with three meals per day, consisting of a big breakfast, average lunch and small dinner, had many rapid and positive effects compared to the traditional diet with six small meals evenly distributed throughout the day: better weight loss, less hunger and better diabetes control while using less insulin.”

The other improvement was a large decrease in overall glycemia within 2 weeks for the high-energy breakfast group.

This was only due to changes in meal timings, suggesting a correct meal schedule itself can positively affect blood sugar levels.

The study was presented at the Endocrine Society Annual Meeting 2018 in Chicago.

About the author
Mina Dean is a Nutritionist and Food Scientist. She holds a BSc in Human Nutrition and an MSc in Food Science.
source: Psyblog
breakfast

The Weight Loss Diet That Cuts Belly Fat

The diet helps people control their blood sugar more effectively.

Going on a vegan diet accelerates weight loss and reduces harmful belly fat, new research suggests.

People following a plant-based, vegan diet for 16 weeks lost an average of over 12 pounds, including almost 9 pounds of fat mass and belly fat.

More fibre is the most critical element of the diet, researchers think.

Plant-based diets contain plenty of fibre which helps to boost healthy bacteria in the gut.

The study included 147 overweight people who were randomised to a vegan diet or no change for 16 weeks.

The results revealed that a vegan diet reduced weight significantly.

A vegan diet also helped people control their blood sugar more effectively.

The study’s authors write:

“A 16-week low-fat vegan dietary intervention induced changes in gut microbiota that were related to changes in weight, body composition and insulin sensitivity in overweight adults.”

The diet also increased the health of the gut.

People with a greater abundance of critical healthy bacteria in the gut lost more weight.

Bacteria that a vegan diet boosts include Faecalibacterium prausnitzii and Bacteroides fragilis.

The authors conclude:

“A plant-based diet has been shown to be effective in weight management, and in diabetes prevention and treatment.
We have demonstrated that a plant-based diet elicited changes in gut microbiome that were associated with weight loss, reduction in fat mass and visceral fat volume, and increase in insulin sensitivity.”

Fibre is the key to weight loss and a healthy gut, the authors write:

“The main shift in the gut microbiome composition was due to an increased relative content of short-chain fatty acid producing bacteria that feed on fibre.
Therefore, high dietary fibre content seems to be essential for the changes observed in our study.”

About the author
Psychologist, Jeremy Dean, PhD is the founder and author of PsyBlog. He holds a doctorate in psychology from University College London and two other advanced degrees in psychology.
He has been writing about scientific research on PsyBlog since 2004. He is also the author of the book “Making Habits, Breaking Habits” (Da Capo, 2003) .

The study was presented at the Annual Meeting of the European Association for the Study of Diabetes (EASD) in Barcelona, Spain (Kahleova et al., 2019).

source: Psyblog

 

veggies

Is a Vegan Diet Healthy?

People might change to a plant-based diet because of concerns about animal welfare, the environment or their own health.

But can you be truly healthy on a diet that excludes both meat and dairy?

The answer is a definite yes — but it takes some effort.

Transcript
Dr Karl: G’day, Dr Karl here.

Way back in 1925, Donald Watson was just 14 years old and living with his family on a farm in Great Britain. One day, he saw a pig being slaughtered.

The pig was terrified and screaming.

This moved Donald so much that he stopped eating meat, and then eventually avoided dairy as well. A few decades later, in 1944 he invented the word “vegan” — by joining together the first and last syllables of the word “vegetarian”.

People sometimes wonder if you can be truly healthy on a diet that excludes both meat and dairy. The answer is definitely yes — but you have to understand your food much more deeply than the person living on meat-and-three-veg.

There are many reasons for changing to a plant-based diet. Some include concerns about animal suffering and cruelty, or about health, while other reasons relate to the environment.

From a health point-of-view, plant-based diets have been linked to lower risks of obesity and many chronic diseases, such as type II diabetes, heart disease, inflammation and cancer. And the evidence does link colorectal cancer with red and processed meats.

But these benefits don’t come without risk.

Clare Collins, Professor in Nutrition and Dietetics at the University of Newcastle, says there are four essential nutrients that have to be especially considered if you choose to go vegan. They are vitamin B12, iron, calcium and iodine. If you’re not eating meat or dairy products, you’ll struggle to get a decent supply of them.

Let’s start with vitamin B-12. It’s essential for making DNA, fatty acids, red blood cells and some neurotransmitters in the brain.

A deficiency of B12 can cause a fast heart rate, palpitations, bleeding gums, bowel or bladder changes, tiredness, weakness, and light-headedness — which doesn’t make for a healthy lifestyle.

Vitamin B12 is easily found in animal foods such as meat, milk and dairy products.

But vegans can get only traces of vitamin B12 in some algae and plants that have been exposed to bacteria contaminated by soil or insects, and in some mushrooms or fermented soybeans. So vegans really need to consume foods with vitamin B12 specifically added, like fortified non-dairy milks.

The second micronutrient, calcium, is essential for good bone health – as well as for proper function of the heart, muscles and nerves.

Calcium is abundant in milk and milk-based foods. Vegans can get calcium from tofu, some non-dairy milks with added calcium, as well as nuts, legumes, seeds and some breakfast cereals.

But both vegans and vegetarians usually need a higher calcium intake than meat eaters. That’s because vegetarians and vegans usually eat more plant foods containing chemicals that reduce the absorption of calcium into your body.

These chemicals include oxalic acid (found in spinach and beans) and phytic acid (found in soy, grains, nuts and some raw beans).

Surprisingly, vegans can also be deficient in iodine – which is essential for making thyroid hormones, and the developing central nervous system.

Vegans don’t eat the usual sources of iodine – seafood, dairy products and eggs — but they do eat seaweed, and foods that have added iodine such as salt, some breads, and some non-dairy milks.

So why would vegans be prone to iodine deficiency? Well swallowing iodine is only half the battle — like with calcium, some other foods can reduce your absorption of iodine. If you love your Brassicas – things like cabbage, broccoli, and Brussels sprouts — you’re also getting a dose of chemicals in these vegetables that can interfere with the production of the thyroid hormones.

And finally, we come to iron. Most people know that iron can be a problem on a vegetarian or vegan diet. Iron is essential to make the haemoglobin in your red blood cells, which carry oxygen around your body.

It is easy to get enough iron if you eat wholegrain cereals, meats, chicken and fish. And there is iron in some plants — but your body can’t absorb this type of iron as well as it absorbs iron from meat.

You can boost your absorption of plant iron (or ‘non-haem’ iron) by eating vegetables and fruit that are rich in vitamin C. Just don’t have a cuppa at the same time — tea contains chemicals that can reduce your absorption of plant iron even more!

I did say vegans need to understand food much more deeply than meat-eaters!

And if you’ve been a vegan for long time, the list of nutrients you need to keep an eye on gets longer. You also need to watch your vitamin D, omega-3 fats and protein intake.

Finally, vegans have to take even more care with their diet plans if they are pregnant or breastfeeding, or bringing up the children as vegans. In this case, it’s very worthwhile to get the advice of a professional dietician.

So it does take a bit of effort to get all your nutrients from a vegan diet. But take a look around – it’s not like eating meat and animal products is a sure-fire guarantee of healthy eating!

Credits
Presenter Dr Karl Kruszelnicki            Producer Bernie Hobbs
Tuesday 12 November 2019


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The Vitamin That Quadruples Weight Loss

Taking vitamin D supplements can significantly increase weight loss, according to a recent study.

People who took vitamin D supplements had over four times the weight loss as those that did not, researchers found.

obese

Vitamin D also doubled the number of inches taken off their waistlines.

Low levels of vitamin D is repeatedly linked to being overweight and obese.

Almost 40 percent of obese people are deficient in vitamin D.

The study included 400 obese and overweight people with vitamin D deficiency.

They were put on a low-calorie diet and split into three groups.

One group took 25,000 IU of vitamin D per month, the second took 100,000 IU of vitamin D per month and the control group took none.

Six months later the results showed that both vitamin D groups had lost more weight than those who were not taking the vitamin.

Those taking 100,000, or around 3,000 IU per day, had 12 pounds of weight loss.

People taking 25,000 IU, or around 800 IU per day, lost 8 pounds.

In comparison, those only following the calorie restricted diet had just 2.6 pounds of weight loss over the six months.

The study’s authors write:

“The present data indicate that in obese and overweight people with vitamin D deficiency, vitamin D supplementation aids weight loss and enhances the beneficial effects of a reduced-calorie diet.”

Measurements of dieters’ waistlines also revealed vitamin D had had an effect.

Those taking 100,000 IU lost an average of two inches from their waistline compared to just over 1 inch in the control group.

The researchers conclude:

“All people affected by obesity should have their levels of vitamin D tested to see if they are deficient, and if so, begin taking supplements.”

vitamin d

About the author
Psychologist, Jeremy Dean, PhD is the founder and author of PsyBlog. He holds a doctorate in psychology from University College London and two other advanced degrees in psychology.
He has been writing about scientific research on PsyBlog since 2004. He is also the author of the book “Making Habits, Breaking Habits” (Da Capo, 2003) and several ebooks:

  • Accept Yourself: How to feel a profound sense of warmth and self-compassion
  • The Anxiety Plan: 42 Strategies For Worry, Phobias, OCD and Panic
  • Spark: 17 Steps That Will Boost Your Motivation For Anything
  • Activate: How To Find Joy Again By Changing What You Do

The study was presented at the European Congress on Obesity, 2015 (Vigna et al., 2015).

source: PsyBlog

 

obesity

Gut Bacteria is Key Factor in Childhood Obesity



Summary:
Scientists suggest that gut bacteria and its interactions with immune cells and metabolic organs, including fat tissue, play a key role in childhood obesity.


New information published by scientists at Wake Forest Baptist Health suggests that gut bacteria and its interactions with immune cells and metabolic organs, including fat tissue, play a key role in childhood obesity.

“The medical community used to think that obesity was a result of consuming too many calories. However, a series of studies over the past decade has confirmed that the microbes living in our gut are not only associated with obesity but also are one of the causes,” said Hariom Yadav, Ph.D., lead author of the review and assistant professor of molecular medicine at Wake Forest School of Medicine, part of Wake Forest Baptist.

In the United States, the percentage of children and adolescents affected by obesity has more than tripled since the 1970s, according to the Centers for Disease Control and Prevention. Obesity is increasing at 2.3% rate each year among school-aged children, which is unacceptably high and indicates worrisome prospects for the next generation’s health, the article states.


Yadav’s manuscript, published in the current issue of the journal Obesity Reviews, reviewed existing studies (animal and human) on how the interaction between gut microbiome and immune cells can be passed from mother to baby as early as gestation and can contribute to childhood obesity.


The review also described how a mother’s health, diet, exercise level, antibiotic use, birth method (natural or cesarean), and feeding method (formula or breast milk) can affect the risk of obesity in her children.

“This compilation of current research should be very useful for doctors, nutritionists and dietitians to discuss with their patients because so many of these factors can be changed if people have enough good information,” Yadav said. “We also wanted to identify gaps in the science for future research.”

In addition, having a better understanding of the role of the gut microbiome and obesity in both mothers and their children hopefully will help scientists design more successful preventive and therapeutic strategies to check the rise of obesity in children, he said.

Journal Reference:
Halle J. Kincaid, Ravinder Nagpal, Hariom Yadav. Microbiome‐immune‐metabolic axis in the epidemic of childhood obesity: Evidence and opportunities. Obesity Reviews, 2019; DOI: 10.1111/obr.12963
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Wake Forest Baptist Medical Center.
Source:
Materials provided by Wake Forest Baptist Medical Center. Note: Content may be edited for style and length.

 
ScienceDaily               30 October 2019
 www.sciencedaily.com/releases/2019/10/191030132704.htm


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Household Cleaners May Alter Kids’ Gut Flora And Contribute To Being Overweight, Says Study

Commonly used household disinfectants could increase the risk of young children becoming overweight by altering the makeup of their gut bacteria during the first few months of life, a study suggests.

The study, published Monday in the Canadian Medical Association Journal, analyzed the gut flora of 757 infants at age three to four months and their body mass index, or BMI, at one and three years old, looking at exposure to disinfectants, detergents and eco-friendly products used in the home.

Anita Kozyrskyj, professor of pediatrics at the University of Alberta, is shown in a handout photo. The high use of household disinfectant cleaners is changing the gut flora in babies, leading to them becoming overweight as three-year-olds.

“We found that infants living in households with disinfectants being used at least weekly were twice as likely to have higher levels of the gut microbes Lachnospiraceae at age three to four months,” said principal investigator Anita Kozyrskyj, a professor of pediatrics at the University of Alberta.

Lachnospiraceae is one of many non-pathogenic bacteria that naturally inhabit the human gut.

“When they were three years old, their body mass index was higher than children not exposed to heavy home use of disinfectants as an infant,” she added.

Researchers from across Canada looked at data on microbes in infant fecal matter among children enrolled in the Canadian Healthy Infant Longitudinal Development (CHILD) birth cohort. They used World Health Organization growth charts for BMI scores.

Associations with altered gut flora in babies three to four months old were strongest for frequent use of household disinfectants such as multi-surface cleaners, which showed higher levels of Lachnospiraceae.

Kozyrskyj said researchers also found there was a greater increase in levels of those bacteria in children whose parents reported more frequent cleaning with disinfectants.

“As the microbiome develops over the first year of life, these microbes increase in their abundance. So it was a matter of dose,” she said in an interview, noting that studies of piglets have found similar changes in the animals’ gut microbiome when they were exposed to aerosol disinfectants in their enclosures.

However, the same association was not found with detergents or eco-friendly cleaners, the CHILD study found. Babies living in households that used eco-friendly cleaners had different microbiota and were less likely to be overweight as toddlers.

 

“Those infants growing up in households with heavy use of eco cleaners had much lower levels of the gut microbes Enterobacteriaceae (a family of bacteria that includes E. coli). However, we found no evidence that these gut microbiome changes caused the reduced obesity risk,” Kozyrskyj said.

One reason could be that the use of eco-friendly products may be linked to healthier overall maternal lifestyles and eating habits, contributing in turn to the healthier gut microbiomes and weight of infants.

“Antibacterial cleaning products have the capacity to change the environmental microbiome and alter risk for child overweight,” write the authors. “Our study provides novel information regarding the impact of these products on infant gut microbial composition and outcomes of overweight in the same population.”

There are many findings that point to a possible causative role for disinfectants in altering gut flora and subsequently leading to a higher childhood BMI, said Kozyrskyj, noting that in studies of mice, Lachnospiraceae has been shown to cause insulin resistance and increased fat storage.

“I would be comfortable in saying the high use of disinfectants had a contributory role … My advice would be to not overuse them,” she said.
“Some people might say maybe go for an alternative, go for the eco product instead of the disinfectants as a cleaning agent.”

In a related CMAJ commentary, epidemiologists Dr. Noel Mueller and Moira Differding of the Johns Hopkins Bloomberg School of Public Health write: “There is biologic plausibility to the finding that early-life exposure to disinfectants may increase risk of childhood obesity through the alterations in bacteria within the Lachnospiraceae family.”

They call for further studies “to explore the intriguing possibility that use of household disinfectants might contribute to the complex causes of obesity through microbially mediated mechanisms.”

Kozyrskyj agreed, saying there is a need for further research that classifies cleaning products by their ingredients, with an analysis of their potential individual effects.

Mon., Sept. 17, 2018
 
By SHERYL UBELACKER     The Canadian Press
 


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Probiotic Use is a Link Between Brain Fogginess, Severe Bloating

Probiotic use can result in a significant accumulation of bacteria in the small intestine that can result in disorienting brain fogginess as well as rapid, significant belly bloating, investigators report.

In a published study of 30 patients, the 22 who reported problems like confusion and difficulty concentrating, in addition to their gas and bloating, were all taking probiotics, some several varieties.

When investigators looked further, they found large colonies of bacteria breeding in the patients’ small intestines, and high levels of D-lactic acid being produced by the bacteria lactobacillus’ fermentation of sugars in their food, says Dr. Satish S.C. Rao, director of neurogastroenterology/motility and the Digestive Health Clinical Research Center at the Medical College of Georgia at Augusta University.

D-lactic acid is known to be temporarily toxic to brain cells, interfering with cognition, thinking and sense of time. They found some patients had two to three times the normal amount of D-lactic acid in their blood. Some said their brain fogginess – which lasted from a half hour to many hours after eating – was so severe that they had to quit their jobs.

The report in the journal Clinical and Translational Gastroenterology appears to be the first time the connection has been made between brain fogginess, bacterial overgrowth in the small intestine, high levels of D-lactic acid in the gut and probiotic use, Rao says.

“What we now know is that probiotic bacteria have the unique capacity to break down sugar and produce D-lactic acid. So if you inadvertently colonize your small bowel with probiotic bacteria, then you have set the stage for potentially developing lactic acidosis and brain fogginess,” Rao says.

While probiotics can be beneficial in some scenarios, like helping a patient restore his gut bacteria after taking antibiotics, the investigators advised caution against its excessive and indiscriminate use.

“Probiotics should be treated as a drug, not as a food supplement,” Rao says, noting that many individuals self-prescribe the live bacteria, which are considered good for digestion and overall health.

Others have implicated probiotics in the production of D-lactic acid – and brain fogginess – in patients with a short bowel so their small intestine does not function properly, and in newborns fed formula containing the popular product. Short bowel syndrome results in a lot of undigested carbohydrates that are known to cause small intestinal bacterial overgrowth, or SIBO, and the high levels of D-lactic acid. Severe liver and kidney problems can produce similar problems.

Whether there was also a connection when the gut is intact was an unknown. “This is the first inroad,” says Rao.

All patients experiencing brain fogginess took probiotics and SIBO was more common in the brain fogginess group as well, 68 percent compared to 28 percent, respectively. Patients with brain fogginess also had a higher prevalence of D-lactic acidosis, 77 versus 25 percent, respectively.

When brain-foggy patients stopped taking probiotics and took a course of antibiotics, their brain fogginess resolved.

Movement of food through the gastrointestinal tract was slow in one third of the brain foggy patients and one fourth of the other group. Slower passage, as well as things like obesity surgery, can increase the chance of bacterial buildup, or SIBO.

“Now that we can identify the problem, we can treat it,” Rao says. Diagnosis includes breath, urine and blood tests to detect lactic acid, and an endoscopy that enables examination of fluid from the small intestines so the specific bacteria can be determined and the best antibiotics selected for treatment.

Normally there is not much D-lactic acid made in the small intestines, but probiotic use appears to change that. SIBO, which was present in most with brain fogginess, can cause bacteria to go into a feeding frenzy that ferments sugars resulting in production of uncomfortable things like hydrogen gas and methane that explain the bloating.

probiotics

Probiotics added to that feeding frenzy the bacterium lactobacillus, which produces D-lactic acid as it breaks down sugars, The acid get absorbed in the blood and can reach the brain.

All those with brain fogginess, SIBO and/or D-lactic acidosis, were given antibiotics that targeted their bacterial population and asked to discontinue probiotics. Those without SIBO were asked to halt probiotics and stop eating yogurt, which is considered one of the best sources of probiotics. Those with SIBO and D-lactic acidosis but no brain fogginess also took antibiotics.

Following treatment, 70 percent of patients reported significant improvement in their symptoms and 85 percent said their brain fogginess was gone. Those without brain fogginess but with SIBO and high levels of D-lactic acid reported significant improvement in symptoms like bloating and cramping within three months.

Abdominal pain was the most common symptom in both groups and before treatment, six of those with brain fogginess reported a tremendous increase in their abdominal size within just a few minutes of eating.

All patients received extensive examination of their gastrointestinal tract, including a motility test, to rule out other potential causes of their symptoms. They filled out questionnaires about symptoms like abdominal pain, belching and gas and answered questions about related issues like antibiotic and probiotic use as well as food fads and yogurt consumption.

They were given carbohydrates followed by extensive metabolic testing looking at the impact on things like blood glucose and insulin levels. Levels of D-lactic acid and L-lactate acid, which results from our muscles’ use of glucose as energy and can cause muscle cramps, also were measured.

Probiotic use may be particularly problematic for patients who have known problems with motility, as well as those taking opioids and proton pump inhibitors, which reduce stomach acid secretion and so the natural destruction of excessive bacteria.

Probiotics are supposed to work in the colon and not the small intestines or stomach, Rao says, so motility issues can result in problems with probiotic bacteria reaching the proper place. A wide variety of problems, from conditions like diabetes to drugs like antidepressants and minerals like iron, can slow movement and increase the possibility that probiotics will remain too long in the upper gut where they can cause harm, he says.

Probiotics definitely can help, for example, people who have gastroenteritis, or stomach flu, or are left with diarrhea and other problems after antibiotics wipe out their natural gut bacteria, Rao says.

“In those situations, we want to build up their bacterial flora so probiotics are ideal,” he says.

Rao’s pursuit of a possible connection between probiotics, brain fogginess and bloating started with a memorable patient who developed significant amounts of both problems within a minute of eating.

“It happened right in front of our eyes,” Rao says of the dramatic abdominal distention. They knew the woman had diabetes, which can slow motility. When they looked in the blood and urine at a variety of metabolic compounds, they found the high levels of D-lactic acid and soon learned the patient used probiotics and regularly ate yogurt.

Next steps include additional studies in which the investigators better quantify and characterize the brain fogginess reported by patients and following patients for longer periods to ensure their problems remain resolved. Some patients in the current study required a couple of rounds of antibiotics, Rao notes.

Good food sources of probiotics include yogurt, sauerkraut, kimchi, kefir and dark chocolate, which are generally safe because of the small amounts of bacteria present, Rao says.

The 19-foot long small intestine has been a bit of an understudied organ, likely in part because it’s hard to visualize via the mouth or anus, Rao says. “I think the small bowel can be a source of huge mystery,” Rao says.

Your helpful gut bacteria, or microbiome, which are essential to things like a well-functioning immune system and general health, are largely in the large intestine and colon.

 

Story Source:
Materials provided by Medical College of Georgia at Augusta University.
Note: Content may be edited for style and length.
August 6, 2018
 
Journal Reference:
Satish S. C. Rao, Abdul Rehman, Siegfried Yu, Nicole Martinez de Andino.
Brain fogginess, gas and bloating: a link between SIBO, probiotics and metabolic acidosis.
Clinical and Translational Gastroenterology, 2018; 9 (6) DOI: 10.1038/s41424-018-0030-7


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Massive Study Yields Exciting Findings about Gut Health and the Microbiome

Gut health could be the biggest trend in the health field right now. Everywhere I turn people are discussing the importance of their gut health and how it is linked to their overall health, as well as the benefits of probiotics. And, for good reason: a growing body of research shows that what happens in our gut expands well beyond the gut.

Now new research shows that the health of your gut is significantly influenced by what you eat. A new study assessed 15096 fecal samples provided by 11336 people, published in the journal of the American Society for Microbiology, found some exciting facts about gut health and the microbiome, which is the total of all the microbes in a living being.

We each have a microbiome and no two microbiomes are alike, although there can be some similarities between them. The microbiome is a sort of microbial fingerprint. And, thanks to the new research, we have greater insight into the effect of diet on our microbiome. Here are some of the findings from this exciting study:

1) Plant-based diets produce the most diverse microbiomes. Diverse microbiomes seem to confer health benefits. Consider people who struggle to lose weight: earlier research in the journal Beneficial Microbes shows that they tend to have less diverse strains of beneficial bacteria and a lower ratio of beneficial microbes to harmful ones.

2) Eating more than 30 types of plant foods weekly yields the most diverse microbiome. In other words, it’s important to eat a plant-based diet but also one that has tremendous diversity. So, expand your horizons when it comes to trying new vegetables, fruits, nuts, seeds and grains. Your microbiome will thank you. And, who knows? You might even discover a new favorite food.

3) There is a lower incidence of bacterial resistance in those who eat the greatest variety of plant foods weekly. This is great news since more and more varieties of harmful bacteria like E. coli and MRSA are, not only becoming more prevalent, they are also becoming resistant to the typical drug treatment: antibiotics. This is an astounding discovery on its own. We tend to assume that all of a certain variety of bacteria have the same level of potency against humans, but the research shows that people who eat a large variety of plant-based foods are less likely to be host to these disease-causing, resistant bacteria. People who ate more than 30 types of plant foods weekly had less resistance to antibiotics.

4) The gut bacteria of people suffering from mental health issues, including: post-traumatic stress disorder (PTSD), schizophrenia, depression or bipolar disorder were more similar to others suffering from mental disorders than to those who do not suffer from mental disorders. While the scientists conducting the study did not draw any conclusions, there may be a possible connection between gut health and mental health. Certainly other research suggests that is indeed the case. Research in the Journal of Physiological Anthropology found a link between gut bacteria and increased activity in brain pathways that improve brain health and reduce depression risk.

microbiome

How can you reap the benefits of this exciting research?

There are endless ways to boost the variety of plant-based foods you consume, but the following ones should help you get started:

  1.    Start by replacing meat in your diet with plant-based options. Start with Meatless Mondays but don’t hesitate to go meatless the rest of the week as well
  2.    The next time you pass by that odd-looking fruit or vegetable in the produce section of your grocery store, add it to your cart. It’s easy enough to find recipes for lesser-known foods using a quick Internet search. And, most importantly, add the food to your diet.
  3.    Instead of just snacking on almonds or another nut, branch out to try Brazil nuts, cashews, hazelnuts, pecans, pistachios, etc. Choose raw, unsalted varieties.
  4.    Rather than just add a can of kidney beans to your soup, stew, or chili, opt for bean varieties you are less familiar with. That could include: chickpeas, lentils, pinto beans, Romano beans, black beans, navy beans, etc.
  5.    The next time a snack attack strikes, choose a piece of fruit or a bowl of mixed berries.
  6.    When you have a craving for salty foods, choose traditionally-fermented pickles, pickled green beans, pickled beets or other foods with live cultures. Not only will you be getting a wider variety and a greater quantity of plant-based foods, you’ll also help expand the beneficial microbes you consume. Be sure to choose pickled foods that state “live cultures” or “unpasteurized” on the label.

 

Dr. Michelle Schoffro Cook, PhD, DNM is the publisher of the free e-newsletter World’s Healthiest News, the Cultured Cook, co-founder of BestPlaceinCanada, and an international best-selling and 20-time published book author whose works include: The Cultured Cook: Delicious Fermented Foods with Probiotics to Knock Out Inflammation, Boost Gut Health, Lose Weight & Extend Your Life.

By: Michelle Schoffro Cook May 31, 2018
 Follow Michelle at @mschoffrocook
 
source: www.care2.com


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The Type of Probiotic That May Reverse Depression

The probiotic buffered the body against the damaging effects of stress.

Depression has been reversed in mice by feeding them probiotic bacteria, new research reports.

Lactobacillus is a type of ‘good’ bacteria found in yogurt, among other foods.

The role of the gut microbiome — the bacteria which live in our gut — has become a focus of research interest recently.

Dr Alban Gaultier, who led the study, said:

“The big hope for this kind of research is that we won’t need to bother with complex drugs and side effects when we can just play with the microbiome.
It would be magical just to change your diet, to change the bacteria you take, and fix your health — and your mood.”

The scientists found that when mice in the study were put under stress, the bacteria in their gut changed.

The main change was a reduction in Lactobacillus, which was linked to depressed behaviour in the mice.

Feeding them Lactobacillus almost completely stopped their depressive behaviours.

pickles

The researchers found a mechanism for how this change in the gut led to depression (it is through a metabolite called kynurenine).

First author, Ms Ioana Marin said:

“This is the most consistent change we’ve seen across different experiments and different settings we call microbiome profiles.
This is a consistent change.
We see Lactobacillus levels correlate directly with the behavior of these mice.”

The researchers plan to continue investigating kynurenine’s role in depression, Ms Marin said:

“There has been some work in humans and quite a bit in animal models talking about how this metabolite, kynurenine, can influence behavior.
It’s something produced with inflammation that we know is connected with depression.
But the question still remains: How?
How does this molecule affect the brain?
What are the processes?
This is the road we want to take.”

The study was published in the journal Scientific Reports (Marin et al., 2017).
MARCH 15, 2017
source: PsyBlog


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The Microbiome: The Key to Optimal Health

Here’s how the microbiome—the colony go micro-organisms that lives on and in our bodies—might hold the key to a healthy immune system, mood and weight, and our overall well-being.

micro-organisms that lives on and in our bodies—
might hold the key to a healthy immune system, mood and weight, and our overall well-being.

Imagine that from the time you’re born, your body is hosting a daily house party. Who’s on the guest list? Roughly 40 trillion of your tiniest, closest friends. And like any lively party, there’s a mix of good and bad guests. This community of micro-organisms, which includes bac­teria, viruses, fungi and yeast, is collectively known as microbiota, or our microbiome. It’s often called the ‘forgotten organ’ and could be considered one of our largest in terms of cells. In fact, recent research suggests that we have around the same number of bacterial cells as human cells. During a natural birth, you’re first exposed to bacteria from your mother, and it’s estimated that your ecosystem is largely established by age three. We’re used to thinking of bugs as unwanted party crashers, but researchers are discovering that they play an important role in our overall well-being and may hold the key to a host of health-related issues.

MEET YOUR MICROBIOME
If it seems like the word micro­biome just recently appeared on your radar, you’re not alone. It was only in 2008 that the National Institutes of Health Common Fund’s Human Microbiome Project was established to under­stand the microbiome and how it impacts the way our bodies function.

‘We knew that the microbiome was there, but we thought of it only as external and not really in our body. As research expands in this area, we’re discovering how much influence it has on well-being,’ says Kathy McCoy, the director of the Western Canadian Microbiome Centre and a professor at the Cumming School of Medicine in Calgary. ‘One thing we know for sure is that good bacteria benefit our health.’

HAPPY GUT = HEALTHY LIFE
Our gut houses the bulk of our bugs and can carry more than 1,000 different species. The hot spot is the large intestine, which is the most highly colonized by bacteria. ‘Bacteria help us digest foods we otherwise couldn’t, such as complex carbohydrates,’ says McCoy. ‘They increase our meta­bolic capacity, produce vitamins we can’t make ourselves and break down food so our bodies get needed nutrients.’

A healthy gut can determine which nutrients are absorbed and which toxins are blocked. ‘The state of our gut microbiota has drastically changed as we’ve transformed our diets, specifically due to a loss of fibre intake,’ says McCoy. ‘The consumption of more processed foods has negatively influenced the makeup of our microbiota.’

The key to a well-functioning microbiome is a diversity of good bacteria. The latest research shows how our micro­biome can affect our immunity, weight and mood, and reveals how you can nurture and strengthen your gut to improve your health.

BOOST YOUR IMMUNITY
‘Unlike genes or genetic disorders that are hardwired, we can manipulate our microbiome to some degree,’ says McCoy. By nurturing our gut to create a healthy microbiota, we equip it with better ammunition to fight potential invaders, such as bad bacteria (salmonella, for example), making it a strong ally for our immune system.

‘Over the past 50 years, in developing countries, the prevalence of autoimmune diseases, such as rheumatoid arthritis, Type 1 diabetes and celiac disease, has skyrocketed—and some, like Type 1 diabetes, are occurring at a younger age. At the same time, there’s a strong belief that the diversity in our microbiota has decreased,’ she says. By not supporting and nurturing our microbiome, we leave it less able to protect itself and more vulner­able to invaders. ‘The immune system in your gut needs to be equip­ped like an army, alert to recog­nize potential danger and armed to fight disease-causing microbes and pathogens,’ says McCoy.

MAINTAIN A HEALTHY WEIGHT
Trying to shed a few pounds? Take a closer look at the health of your gut flora. ‘A study found that the micro­biota from obese people thrives on low-fibre, high-fat and high-sugar diets,’ says McCoy. Also, research suggests that certain bugs may make you desire specific foods, yet others can keep cravings in check. And multiple studies have demonstrated that if your microbiome is unbalanced, it can affect how efficiently food is metabolized.

IMPROVE YOUR MOOD
There might be more to that ‘gut feeling’ we get. ‘There’s evidence that some bacteria residing in the gut can affect the brain and your emotional state,’ says McCoy. Researchers are working to unlock the gut-brain connection and believe that the micro­biome could hold the answer to a number of mental health conditions. ‘Researchers are finding that changes in the microbiota might be linked to gastrointestinal abnormalities, including anxiety, depr­es­sion, autism and hyperactivity. And there are also studies focusing on the pathway between the gut and several neurological disorders, such as Alzheimer’s disease and Parkinson’s disease,’ says McCoy.

4 WAYS TO SUPPORT YOUR MICROBIOME

1. Feed your microbiome 
One of the best—and easiest—ways to positively impact the gut is through diet. Start by increasing your fibre intake, found in grains, fruit and vegetables. Aim for 25 grams of fibre a day. Avoid high-fat and high-sugar diets, as they promote an unhealthy environment. Instead, eat foods that are full of variety, and include an abundance of fresh produce.

2. Fuel it with fermented foods
Populate the gut with good bacteria by filling up on foods with live and active cultures, such as kefir and some yogurts, and raw, unpasteurized fermented foods, such as kimchi, pickled vegetables and sauerkraut. Support digestive health and nourish the gut lining to more efficiently absorb nutrients by adding a scoop of a fermented yogurt protein powder to your morning smoothie.

3. Pop a probiotic 
‘Although our bodies have bacteria, environmental chemicals, poor nutrition, stress and medication easily affect their diversity. Choose a probiotic with 50 to 100 billion active bact­e­ria,’ says Toronto-based naturopathic doctor Sara Celik. We like a probiotic that’s jam-packed with 50 billion active cultures from 10 strains of bacteria, which is ideal for strengthening the immune system.

4. Monitor antibiotic use
Avoid the overuse of antibiotics, which can reduce the number of bacteria in your gut and break down its ability to resist infection from bad bacteria. ‘They’re drugs that don’t discriminate and kill all forms of bacteria—both good and bad—and can adversely alter the composition of your entire gut flora, which, we believe, is contributing to a host of chronic diseases,’ warns McCoy.

BY: GRACE TOBY         OCT 19, 2017 


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Gut Bacteria ‘Boost’ Cancer Therapy

Bacteria living in the murky depths of the digestive system seem to influence whether tumours shrink during cancer therapy, say French and US researchers.

They tested the microbiome – the collection of microscopic species that live in us – in cancer patients.
Two studies, in the journal Science, linked specific species and the overall diversity of the microbiome to the effectiveness of immunotherapy drugs.

Experts said the results were fascinating and held a lot of promise.

Our bodies are home to trillions of micro-organisms and the relationship between “us” and “them” goes far beyond infectious diseases.

The microbiome is involved in digestion, protection from infection and regulating the immune system.

  • Gut bugs ‘help prevent allergies’
  • Parkinson’s disease ‘may start in gut’

Both studies were on patients receiving immunotherapy, which boosts the body’s own defences to fight tumours.

It does not work in every patient, but in some cases it can clear even terminal cancer.

Survival

One study, at the Gustave Roussy Cancer Campus in Paris, looked at 249 patients with lung or kidney cancer.

They showed those who had taken antibiotics, such as for dental infection, damaged their microbiome and were more likely to see tumours grow while on immunotherapy.

One species of bacteria in particular, Akkermansia muciniphila, was in 69% of patients that did respond compared with just a third of those who did not.

Boosting levels of A. muciniphila in mice seemed to also boost their response to immunotherapy.
Meanwhile, at the University of Texas MD Anderson Cancer Center, 112 patients with advanced melanoma had their microbiome analysed.

Those that responded to therapy tended to have a richer, more diverse microbiome than those that did not.

And they had different bacteria too. High levels of Faecalibacterium and Clostridiales appeared to be beneficial, while Bacteroidales species were bad news in the study.

‘Game-changing’

Tissues samples showed there were more cancer-killing immune cells in the tumour of people with the beneficial bacteria.

The team then performed a trans-poo-sion, a transplant of faecal matter, from people to mice with melanoma.

Mice given bacteria from patients with the “good” mix of bacteria had slower-growing tumours than mice given “bad” bacteria.

Dr Jennifer Wargo, from Texas, told the BBC: “If you disrupt a patient’s microbiome you may impair their ability to respond to cancer treatment.”
She is planning clinical trials aimed at altering the microbiome in tandem with cancer treatment.
She said: “Our hypothesis is if we change to a more favourable microbiome, you just may be able to make patients respond better.
“The microbiome is game-changing, not just cancer but for overall health, it’s definitely going to be a major player.”

Promising

Mark Fielder, president of the Society for Applied Microbiology and professor of medical biology at Kingston University, said the study showed the importance of understanding the micro-organisms that call our bodies home.

He told the BBC: “It’s really interesting and holds a lot of promise, we need to do more work but there are exciting glimmers here in treating some difficult diseases.
“Some claim the microbiome is the answer to everything, I don’t think that’s the case.
“But once we understand more, it could be that microbiome manipulation is important in changing people’s health.”

Dr Emma Smith from Cancer Research UK, said: “It’s fascinating.

“One of the big challenges for using immunotherapies to treat cancer is understanding which patients will respond, and this research is a step towards helping doctors to identify these people.”

By James Gallagher    Health and science correspondent, BBC News    3 November 2017 
 
source: www.bbc.com


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Boost Bacteria to Bolster Your Brain

How can boosting bacteria in your body improve your brain health? Called the “second brain” by leading scientists, a healthy balance of flora in the gut helps to determine whether you’ll have a great memory and a strong resistance to brain disease.

And what happens in the gut plays a significant role in your brain health.  Restoring beneficial bacteria and some healthy yeasts in your intestines (yes, some yeasts are beneficial, just not the ones that cause yeast infections) can go a long way toward protecting your mental faculties and preventing brain diseases altogether.

Frequently when I tell people about this connection between intestinal and brain health—what is known as the gut-brain axis, they tell me that they are covered because they eat yogurt on a regular basis.  While yogurt may (or may not) help boost intestinal flora depending on whether it contains any live cultures at all, we need to give our guts a lot more than yogurt to help us establish a strong and healthy brain for life.

Let’s explore some of the exciting research into the link between beneficial microbes in our gut and our overall brain health.

Some probiotics actually function as antioxidants within the body, which can not only reduce the effects of free radical damage and aging, it is especially good news in the prevention and treatment of brain diseases.

That’s because the brain is vulnerable to free radical damage. Additionally, research at the University of California at Los Angeles (UCLA) found that consuming certain strains of probiotics could actually produce many brain health benefits, including improved sensory and emotional processing.

Since the brain plays a significant role in whether we suffer from mental health conditions like anxiety and depression, probiotics may also be helpful in addressing these serious health concerns. In animal studies conducted by the Department of Medicine at McMaster University, Hamilton, Ontario, Canada, and published in the medical journal Gastroenterology, the probiotic Bifidobacterium longum eliminated anxiety and normalized behavior.  It appeared to work by reducing the excitability of the nerves in the gut that connect through the vagus nerve to the central nervous system, and in doing so, eliminated anxiety.

Hungarian researchers found that intestinal inflammation is one of the key factors involved in depression and that treating the inflammation with probiotics (along with B complex vitamins, vitamin D, and omega 3 fatty acids) reduced depressive symptoms.

Additional French research demonstrates the power of boosting specific strains of probiotics to boost mood and psychological health.  They found that healthy study participants experienced reduced psychological stress, depression, anxiety, and anger and hostility, as well as improved problem-solving skills when taking the Lactobacillus helveticus and Bifidobacterium longum for 30 days.

While you can still enjoy yogurt if you are already doing so, please keep in mind that the above strains are not typically found in yogurt.  I’m not aware of any yogurt that contains the best brain-boosting strains.

Take a probiotic supplement containing proven strains of brain-boosting probiotics such as  Lactobacillus plantarum, Bifidobacterium longum, and Lactobacillus helveticus on a daily basis.  Store your probiotics in the refrigerator, and take them on an empty stomach. First thing in the morning with a large glass of water tends to work well for most people.

Additionally, kimchi—the national dish of Korea which is typically a fermented mixture of cabbage, chilis, and garlic—frequently contains a much more diverse group of beneficial microbes than yogurt, making it an excellent choice as a brain boosting food. Some types contain fish sauce so if you’re vegan be sure to choose a fish sauce-free option. It is delicious on sandwiches, over brown rice, or as a side-dish to many foods.  Be sure to choose kimchi that hasn’t been pasteurized to ensure the cultures are still intact.

By: Michelle Schoffro Cook           October 5, 2017
source: www.care2.com