The most recent trial confirms that two nutrients can reduce deaths from heart attacks and cancer.
Omega-3 fatty acids from fish oil can significantly reduce heart attacks and vitamin D supplementation can significantly lower the number of deaths caused by different types of cancer.
Researchers studied 26,000 American adults in the VITAL clinical trial for five years to see if fish oil or vitamin D would definitely ward off cardiovascular disease or cancer.
The outcomes were reassuring: marine omega-3 fatty acid intake was linked to a significant drop in heart attacks.
One-and-half servings per week of dietary fish intake showed the maximum heart health benefits, but higher dietary fish intake didn’t help more.
The greatest decrease in heart attacks was seen in African-Americans.
The benefit of 1 gram of omega-3 fish oil supplementation showed a small decrease in major cardiovascular events like stroke and death from cardiovascular disease.
Vitamin D3 or cholecalciferol intake at a dose of 2000 IU per day showed a significant decrease of death from cancer for those who took it for at least two years.
However, supplementation with vitamin D3 capsules didn’t significantly lower incidence of any type of cancer or cardiovascular disease.
Dr. JoAnn Manson, the study’s first author, said:
“The pattern of findings suggests a complex balance of benefits and risks for each intervention and points to the need for additional research to determine which individuals may be most likely to derive a net benefit from these supplements.”
Dr. Stephanie Faubion, NAMS medical director, said:
“With heart disease and cancer representing the most significant health threats to women, it is imperative that we continue to study the viability of options that prevent these diseases and help women survive them.”
The 1 gram omega-3 fish oil supplementation used in the VITAL clinical trial was Omacor, a prescription medicine for adults.
The capsule contains 840 milligrams marine omega-3 fatty acids, of which 465 mg is eicosapentaenoic acid (EPA) and 375 mg is docosahexaenoic acid (DHA).
The study was presented at the North American Menopause Society (NAMS) Annual Meeting in Chicago (Manson et al., 2019).
About the author ~ Mina Dean is a Nutritionist and Food Scientist. She holds a BSc in Human Nutrition and an MSc in Food Science.
It’s normal to feel anxious or worried from time to time. Work deadlines, writing an exam or giving a presentation, for example, can trigger short-lived anxiety.
People with an anxiety disorder, however, experience persistent and intense anxiety, worry or fear that’s out of proportion to everyday occurrences. Symptoms interfere with daily life, impacting thoughts, emotions, behaviour and physical health. Anxiety disorders include panic disorder, phobias, social anxiety disorder and generalized anxiety disorder (excessive worry about ordinary, everyday situations). Anxiety often goes hand in hand with depression.
Growing scientific evidence suggests that the foods we eat – and the ones that we don’t – play a role in developing and treating anxiety.
The diet-anxiety connection
Components in whole foods can influence mood in a number of ways. Some nutrients are used to synthesize brain chemicals (neurotransmitters) that regulate emotions, while others impact how the brain responds to stress.
An imbalance of omega-3 fats, which are essential for the integrity of brain cell membranes, may alter how brain cells communicate with one another. Certain nutrients may also dampen inflammation in the brain.
While diet can’t cure anxiety – nor can it take the place of medication – research suggests that the following strategies may help reduce symptoms.
Follow a healthy dietary pattern. Studies conducted in many different countries have found that healthy traditional diet patterns, including the Mediterranean diet and vegetarian diets, are associated with a lower risk of anxiety disorders.
In general, eating a diet that’s low in added sugars and emphasizes vegetables, fruits, whole grains, lean proteins, nuts and beans and lentils guards against anxiety. In contrast, a “Western-style” diet consisting of refined grains, highly processed foods and sugary foods increases the risk.
Include omega-3′s, fatty fish. Observational studies have linked a higher intake of oily fish and DHA (docosahexaenoic acid), an omega-3 fatty acid found in fish, to a lower risk of anxiety disorders in children, adults and pregnant women.
A randomized controlled trial published in 2013 found that medical students who received omega-3 supplements (2.5 grams a day) experienced a 20-per-cent reduction in anxiety compared with the placebo group. They also had lower blood levels of stress-induced inflammatory proteins.
Salmon, trout, sardines, herring, mackerel and anchovies are good sources of omega-3 fatty acids; these fish are also low in mercury. Include them in your diet at least twice a week. DHA supplements made from algae are available for people who eat a vegetarian diet.
Try fermented foods. Preliminary evidence suggests that a regular intake of fermented foods, a source of probiotic bacteria, may reduce the risk of social anxiety in women. Fermented foods include kefir, kombucha, kimchi, unpasteurized sauerkraut and yogurt.
Probiotics may also help ease anxiety symptoms. A review of 10 randomized controlled trials, published in 2017, concluded that probiotic supplements significantly improved anxiety. However, the strain of probiotic, the dose and the duration of treatment varied widely across studies.
Once consumed, probiotic bacteria take up residence in the gut, where they help to maintain a strong intestinal barrier. When the lining of the gut becomes more permeable than normal, toxins can escape into the bloodstream, triggering an inflammatory response that may interfere with neurotransmitters.
It’s also thought that probiotics in the gut increase the production of serotonin, a neurotransmitter that regulates stress and emotions.
Increase magnesium, zinc. Findings from a number of studies have shown that a deficiency of these two minerals, needed for healthy brain cells, can lead to anxiety.
Excellent sources of magnesium include oat bran, brown rice, quinoa, spinach, Swiss chard, hemp seeds, pumpkin seeds, almonds, cashews, black beans, lentils, tofu and edamame.
You’ll find zinc in oysters, beef, crab, pork, chicken, pumpkin seeds, cashews, chickpeas, yogurt, milk and fortified breakfast cereals.
Avoid triggers. Eat at regular intervals during the day to prevent low blood sugar, which could precipitate feelings of anxiety. Limit or avoid caffeine and alcohol, which can also make you feel jittery and nervous.
Drink water throughout the day to prevent becoming dehydrated; even mild dehydration can worsen your mood.
LESLIE BECK THE GLOBE AND MAIL August 23, 2020
Leslie Beck, a Toronto-based private practice dietitian, is Director of Food and Nutrition at Medcan.
9 Foods That Calm Anxiety
(and 3 That Make It Worse)
Scientists are just beginning to recognize the connection between food and our brain. Eat these nutrients for a wave of calming feelings that keep worry away.
Omega-3 fatty acids make your brain happy
Doctors often know how to calm anxiety, or treat it, with therapy and medications, but the answer to calming the condition could be hiding in plain sight: the foods we eat. Doctors and nutritionists are starting to understand more about how certain nutrients, or lack of them, affect the brain. “Our brain has very high energy and nutrient requirements,” says clinical nutritionist and health coach Melissa Reagan Brunetti, CNC. “Nutritional deficiencies and dietary patterns can affect its function, and alter brain chemistry and the formulation of neurotransmitters—chemicals in the brain that can stimulate and calm.” These neurotransmitters influence our mood as well as our appetite, she says. A study from Ohio State University showed one nutrient that’s especially good for reducing anxious symptoms is omega 3 fatty acids, found in fatty fish like wild salmon, flaxseed, walnuts, and chia seeds. “Our brains need fat from dietary sources to function properly,” Brunetti says. “If you are not eating a sufficient amount of beneficial fats, your brain will suffer.”
Probiotics are good for the gut
Surprisingly, another calming food source is probiotics. “Your gut bacteria is needed for production of neurotransmitters, including serotonin, dopamine, and GABA [gamma-aminobutyric acid], which all play a role in mood,” Brunetti says. “The microbiome [gut bacteria] has a direct link to the brain and the immune system, so restoring balance in the gut of good and bad bacteria through use of probiotics can benefit the brain.” Recent research has found that probiotics may actually work to treat, or even prevent, anxious feelings. You can either take a probiotic supplement or eat foods that have been fermented, a process which encourages good bacteria to grow, and has been shown in studies as a way how to calm anxiety. “I like to see patients eat more fermented foods like yogurt, sauerkraut, and kefir, as the kinds of bacteria in your gut influence anxiety,” says Drew Ramsey, MD, a psychiatrist who specializes in using dietary changes to help balance moods, and author of Eat Complete. Another fermented food you probably already have in your fridge? Pickles!
Caffeine makes you anxious
Although some of us feel like we’re miserable until we’ve had our morning cup of java, coffee and other caffeinated foods and drinks actually worsen anxious feelings. Because it’s a stimulant for the nervous system, it increases heart rate, blood pressure, and body temperature. According to the University of Michigan, coffee can lead to symptoms of worrying like nervousness, sweating, and shaking. A study from Brazil found that caffeine actually induced panic attacks in people with an anxious disorder. Another study, from Wake Forest University, found that caffeine reduced blood flow to the brain by 27 percent. Not to mention that it can mess with sleep, which is essential for brain health. “Limiting caffeine intake can help quell inflammation and contribute to improved brain function,” Brunetti says. Likewise, Dr. Ramsey suggests avoiding energy drinks with caffeine, as well as indulging in too much dark chocolate (stick to one or two squares a day).
Water keeps everything flowing smoothly
How to calm anxiety in one step? Drink good old fashioned water. “Staying hydrated with clean water is very important,” Brunetti says. A study from the University of Connecticut showed that even mild dehydration can cause mood problems. According to the study’s author, Lawrence E. Armstrong, PhD, by the time you feel thirsty it’s too late. “Our thirst sensation doesn’t really appear until we are one or two percent dehydrated,” he says. “By then dehydration is already setting in and starting to impact how our mind and body perform.” The connection behind dehydration and anxious symptoms is not totally known; but the UConn study authors think it may be part of an ancient warning system alerting us to find water for survival. So, you should be sure to consume water throughout the day.
Stay away from refined sugar and processed foods
Sweets and processed foods all are, not surprisingly, bad for your mental health. Sugar and refined carbs cause a spike in blood sugar followed by a sudden drop. A study from Columbia University found that the more refined carbs and sugar women ate, the higher their risk for mood changes and depression. Another study, from the United Kingdom, found that eating processed meat and fried foods had similar responses, possibly because of the link with heart disease and inflammation, which are also associated with mental health problems. “Skip highly processed foods, as these are mainly simple sugars and vegetable oils,” Dr. Ramsey suggests. Instead, try eating more complex carbs like whole grains, which were linked to fewer mental health issues in the Columbia study.
Alcohol brings you down
Alcohol is a depressant but it can also worsen anxiety symptoms. And unfortunately, the two often go hand-in-hand—in a study that took place over 14 years, researchers found that people with social anxiety disorder (SAD) were 4.5 times more likely to develop alcohol dependence. The Anxiety and Depression Association of America says that 20 percent of people with SAD also suffer from alcohol abuse or dependence. Drinking can seem like a good way to calm your nerves, but in reality, it causes spikes and dips in blood sugar, dehydrates you, and causes impaired brain function—all of which can lead to anxious feelings, which then make you want to drink more, creating a vicious cycle. According to the National Institute on Alcohol Abuse and Alcoholism, drinking a lot can cause changes in the brain’s neurotransmitters that may induce these symptoms. For this reason, Brunetti says it’s best to reduce or eliminate alcohol.
Load up on antioxidants
Here’s another reason antioxidants are superfoods: They can help quell anxious moods. “Antioxidants protect the brain against oxidative stress [free radicals],” Brunetti says. “Oxidative stress leads to inflammation, which can impair neurotransmitter production.” Research by the State University of New York found that anxious symptoms are linked with a lower antioxidant state, and that antioxidants could actually help treat mood issues as well. So which nutrients are antioxidants, and which foods contain them? “Diets rich in beta-carotene like carrots, sweet potatoes, squash, spinach, and kale; vitamin C like citrus fruits, red peppers, Brussels sprouts, broccoli, and strawberries; and vitamin E like almonds, avocado, spinach, sunflower seeds, spinach, and sweet potatoes, are essential for supporting optimal brain function,” Brunetti says. Another powerful antioxidant Brunetti says is shown to combat anxious feelings is the trace mineral selenium, found in Brazil nuts, halibut, grass-fed beef, turkey, chicken, and eggs. Also, studies have shown that upping your zinc, which has antioxidant properties, leads to fewer anxious feelings. Cashews are a great source of zinc.
Magnesium is calming
Another nutrient that might stave off anxious symptoms is magnesium. “Magnesium is a calming mineral that has been found to induce relaxation,” Brunetti says. In an Austrian study with mice, diets low in magnesium increased anxious behaviors. Research has shown that magnesium may also help treat mental health issues in humans. According to the University of Maryland Medical Center, inadequate magnesium reduces levels of the neurotransmitter serotonin, and antidepressants have been shown to increase magnesium in the brain—evidence of a positive link. “Magnesium can act at the blood brain barrier to prevent the entrance of stress hormones into the brain,” psychiatrist Emily Deans, MD, writes on Psychology Today. “All these reasons are why I call magnesium ‘the original chill pill.’” Dr. Ramsey suggests eating eggs and greens, like spinach and Swiss chard, for magnesium. Other sources include legumes, nuts, seeds, and avocado.
We usually think of tryptophan as the nutrient in turkey that puts us to sleep after Thanksgiving—and in fact, tryptophan is an amino acid that the body needs to produce the neurotransmitter serotonin, which helps regulate sleep and moods. According to the University of Michigan, tryptophan may help reduce anxious feelings. In one small study, participants who ate a food bar rich in tryptophan reported fewer symptoms than those who ate a bar without tryptophan. More research is needed, but it seems likely that there is a connection. Tryptophan is in most protein-rich foods like turkey and other meats, nuts, seeds, beans, and eggs. (Incidentally, protein is also important for the production on the neurotransmitter dopamine, which can benefit mood as well.)
B vitamins bump up good feelings
Harvard Medical School advises eating foods rich in B vitamins, like beef, avocado, and almonds, to help ward off anxious feelings. “B vitamins have positive effects on the nervous system, and deficiencies have been linked to anxious disorders,” Brunetti says. According to the University of Maryland Medical Center, vitamin B6 helps the body make several neurotransmitters, including serotonin, which influence mood. A study from Australia found that stressed-out workers who were given a high dose of B vitamins felt less strained and in a better mood after 12 weeks. Another study, from the University of Miami, found that depressed adults who took a vitamin B complex had fewer depressive and anxious symptoms after two months. “Another nutrient that seems to matter is choline, found in eggs, which is a cousin of B vitamins,” Dr. Ramsey says. More research is needed, but these results are promising.
Cozy up with herbal teas
So you might not want to indulge in too much coffee, but you can relax with a mug of herbal tea in order to feel less anxious. “Great options for herbal teas are chamomile, skullcap, and kava kava to start,” Dr. Ramsey says. A study from the University of Pennsylvania found that participants who took chamomile for eight weeks experienced fewer anxious symptoms than those that didn’t. However, be aware that kava can interact with anti-anxiety and antidepressant meds, so talk to your doctor first if you’re on them. Plus, it’s so relaxing that high doses of it could impair your ability to drive, according to one study. If you’re using herbs for anxiety, steer clear of ones that are stimulating, such as ginseng, cautions Dr. Ramsey, because they might actually make anxious feelings worse.
It’s not just what you eat, but how
How to calm anxiety? Pay attention to how and when you eat. Bad habits can have a negative effect on anxious moods, which “get worse when people have low blood sugar,” Dr. Ramsey says. “A simple step people often forget is to eat regularly.” Brunetti says if low blood sugar is an issue for you (in other words, if you get “hangry”), eating smaller, frequent meals throughout the day can help. According to Harvard Medical School, there is evidence that our Western diet, with its focus on refined carbs and processed foods, might not be great for anxious moods; instead, Mediterranean or Japanese diets, which include a lot of veggies and fish, may be the way to go. But, be careful of fad diets that eliminate entire food groups. “Diets that are too low in [complex] carbohydrates can also be detrimental” for anxious feelings, Brunetti says. “Include a variety of foods in your diet to ensure you are getting a wide range of nutrients needed to calm the mind.”
Docosahexaenoic acid (DHA) — an omega-3 fatty acid — can improve IQ by 10%, new research finds.
People in the study, who were aged over 65, were given 2g/day of DHA for a year.
A control group was given a placebo of corn oil.
The high quality study involved 240 Chinese individuals.
Their IQ and other measures of cognitive function were tested after 6 and 12 months.
The study’s authors explain the results:
“…oral DHA supplementation (2 g/d) for 12 months beneficially affected global cognitive function, specifically participants’ performance on the Information and Digit Span tasks.”
Brain scans also revealed changes in the hippocampus, an area of the brain critical for memory.
The study’s authors write:
“The hippocampus is a critical brain region for memory formation and plays important roles in the consolidation of information from short-term memory to long-term memory and spatial navigation.
Our results suggest that 12-month DHA supplementation significantly increased hippocampus volume.
Notably, we observed a 6.13% volume increase in the left hippocampus, a 1.89% increase in the right hippocampus, and a 0.29% increase in total hippocampus.”
Best supplement for older adults
with mild cognitive impairment (MCI).
Best supplement combination?
The use of omega-3 to prevent dementia has provided some mixed results.
B vitamins also seem to be important in warding off cognitive decline.
A recent study found that B vitamins combined with omega-3 can help slow mental decline in older people with memory problems.
The study’s first author, Dr Abderrahim Oulhaj explained the results:
‘We found that for people with low levels of Omega-3, the vitamin supplements had little to no effect.
But for those with high baseline Omega-3 levels, the B vitamins were very effective in preventing cognitive decline compared to the placebo.’
Other studies, though, have been less positive about the benefits of omega-3 for cognitive decline.
It is likely that the combination of nutrients — including both B vitamins and omega-3 will turn out to be the crucial factor.
In 2014 North Americans consumed an average of about 27 pounds of high-fructose corn syrup each.
Fructose consumption can damage hundreds of genes.
But the good news is that DHA — an omega 3 fatty acid — can reverse this damage, scientists have discovered.
Fructose is a sugar commonly found in the Western diet.
Most of the fructose in the American diet comes from high-fructose corn syrup or is consumed in sweetened drinks, syrups, honey and desserts.
According to the Department of Agriculture, in 2014 each American consumed about 27 pounds of high-fructose corn syrup.
In addition, most baby food and fruit contains fructose.
However, the absorption of the fruit sugar is mostly slowed down by the fibre in fruit.
On top of that there are other healthy components found in fruit which are important for the body and the brain.
Our brain cell membranes naturally contain DHA but this amount is not enough to fight diseases.
A diet rich in omega 3 fatty acids can help to reverse the damage to the genes caused by fructose.
Dr Xia Yang a senior author of the study at UCLA University explained:
“DHA changes not just one or two genes; it seems to push the entire gene pattern back to normal, which is remarkable.
And we can see why it has such a powerful effect.”
Professor Fernando Gomez-Pinilla, the co-senior author of the paper, pointed out that the only way to get DHA is from our diet:
“The brain and the body are deficient in the machinery to make DHA; it has to come through our diet.
DHA strengthens synapses in the brain and enhances learning and memory.
It is abundant in wild salmon and, to a lesser extent, in other fish and fish oil, as well as walnuts and flaxseed.”
The study was carried out on rats.
They were divided into three groups for six weeks.
During this period one group only drank water with no fructose and no DHA.
The second group consumed fructose water and a DHA rich diet.
The other group received water with fructose equivalent to a litre of soda per day.
The tests run on the rats showed that a high-fructose diet impaired the rats’ memory.
However, the fructose and DHA group showed similar results to those that drank only water.
This strongly suggested that the harmful effects of fructose were eliminated by DHA.
The study showed that fructose had altered more than 700 genes in the hypothalamus (the metabolic control centre in the brain) and more than 200 genes in the hippocampus (a brain region for regulating memory and learning).
The alteration in human genes could lead to conditions such as bipolar disorder, Parkinson’s disease, depression and other brain diseases.
More tests on the rats also showed that those on a high-fructose diet had higher triglycerides, glucose and insulin levels.
These are similar indicators associated with obesity and diabetes in humans.
What’s worse than not being able to remember something when it’s right on the tip of your tongue? It’s infuriating. And worse, it only happens more frequently as the years pass. But, luckily, there are certain foods, supplements and tricks that can help you sharpen your memory and keep it way. Here are six easy ways to start improving your memory now!
1. Coconut Oil: Researchers are growing more and more optimistic about the relationship between coconut oil and memory preservation. One prominent researcher, Dr. Mary Newport, discovered that coconut oil showed exceptional promise with regards to dementia and Alzheimer’s prevention, as the medium-chain triglycerides found in coconut oil fuel certain brain cells that have a difficult time utilizing carbohydrates, the brain’s main energy source. (Read more about coconut oil and it’s benefits for brain health)
2. DHA from Fish and Fish Oil: While the brain’s main energy source is glucose, it’s building blocks are primary comprised of fatty acids, more specifically, docosahexaenoic acid (DHA). DHA makes up 70% of myelin, the protective sheath that lines active, communicating neurons. Without an abundance of DHA available, brain cell communication stands to be significantly compromised, inhibiting recall and jeopardizing brain health.
3. Crossword Puzzles and Brain Teasers: Crossword puzzles and brain teaser exercises keep parts of the brain active that may otherwise fall into a rut. The important thing is to become engaged in different types of puzzles as they each stimulate the brain differently, according to Ed Zimney, MD, Medical Director of HealthTalk Inc. He says, “Crossword puzzles challenge the language and memory areas [of the brain] while jigsaw puzzles provide exercise for the parietal lobes.” He urges, however, to find crossword puzzles from varying sources and editors as your brain is otherwise likely to become use to the style and receive fewer benefits.
4. B-vitamins: B vitamins provide a tremendous benefit to brain health. The B vitamin family is associated with healthy nerve maintenance and and the production of DNA. Studies have also indicated that B12 prevents brain shrinkage, making this vitamin and it’s benefits an area of interest for researchers as reduced brain size is commonly seen among those with dementia and Alzheimer’s. (Read more about brain health and vitamin B12)
5. Curcumin: Among my favorite of the brain and memory protecting substances, the curcumin spice was first discovered for his brain health benefits when epidemiological studies revealed that regions with a high consumption of curry had fewer reported cases of Alzheimer’s disease. It is theorized that the anti-inflammatory spice with powerful antioxidant properties inhibits the formation of amyloid plaque, a major cause of dementia. (Read more about curcumin and it’s potential for brain health)
6. Berries: The antioxidants in berries provide incredible cell protection throughout your entire body, but the antioxidant family known as anthocyanidins, found in fruits such as blueberries, strawberries, cherries and elderberries, have proven to provide powerful protection to brain cells. Unlike several other antioxidants, anthocyanidins have the ability to cross the blood-brain barrier, providing exceptional protection the brain cells.
Sleeplessness among children is common, occurring in as many as 40% of kids. Sleep deprivation can crescendo into a variety of other problems, including fatigue, declining school performance, depression, behavioral issues, weight gain and even poor general health.
An Oxford University study recently published in the Journal of Sleep Research reveals findings that provide valuable insights about causes of sleeplessness in children. More importantly, the study sheds light on a nutrition-oriented approach to improving sleep.
The researchers evaluated the sleep patterns of 395 children aged 7 to 9. In addition, they performed a blood analysis on these children to measure their levels of DHA, an omega-3 fatty acid.
As had been reported in earlier studies, the number of children having trouble with sleep is a significant 30 to 40%. When the researchers looked specifically at the measurements of total nightly sleep, they discovered a correlation with blood DHA levels. Specifically, lower levels of DHA correlated with a reduction in sleep duration, while higher blood DHA levels were associated with significantly better, longer sleep.
To test whether or not sleep could be improved by raising DHA levels, the researchers administered DHA (derived from marine algae) or a placebo to a smaller number of children for 16 weeks. These children were then evaluated in terms of their sleep performance using a technique called actigraphy. The technique provides an in-depth analysis of sleep duration, number of night-wakings and even actual quality of sleep.
The study revealed that children who received the DHA showed not only better quality sleep, but significantly fewer and shorter night-wakings. They also experienced an increase in sleep duration by nearly one hour.
How DHA directly relates to sleep in children remains unknown and requires additional research. However, in discussing their findings, the authors speculated that the correlation between DHA and sleep in children may be related to the relationship between DHA levels in the brain and the production of the hormone melatonin, which is known to play an important role in sleep regulation.
Adequate, restorative sleep is a fundamental requirement for healthy brain function. This new report provides some actionable information for health professionals and parents who are exploring options to help children obtain the rest they need. For example, parents can manage their child’s diet and nutrition to ensure the foods they are eating include omega-3 DHA, such as fatty fish like salmon.
If food alone is not providing adequate amounts of DHA, parents can look for high-quality fish and plant-based DHA supplements available in most grocery stores and pharmacies.